Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Seu-Na Lee"'
Autor:
Seu-Na Lee, Hwa-Jin Cho, Hyeongseop Jeong, Bumhan Ryu, Hyuk-Joon Lee, Minsoo Kim, Jejoong Yoo, Jae-Sung Woo, Hyung Ho Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Connexin 36 (Cx36) gap junction channel is responsible for signal transmission in electrical synapses. Here, the authors determine cryo-EM structures of Cx36, providing insights into a potential role of lipids in the channel gating.
Externí odkaz:
https://doaj.org/article/be34f9ad35c84967aec756611a123668
Autor:
Hyuk-Joon Lee, Hyung Jin Cha, Hyeongseop Jeong, Seu-Na Lee, Chang-Won Lee, Minsoo Kim, Jejoong Yoo, Jae-Sung Woo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Gap junction intercellular channels (GJIChs) facilitate direct communication between adjacent cells. Here, authors provide high-resolution information on dynamic structural changes in Cx43 GJICh that are necessary to understand the gating mechanism.
Externí odkaz:
https://doaj.org/article/3ade39c189824e13bf2b039251b987e1
Autor:
Ji-Hun Kim, Hyung-Sik Won, Won-Su Yoon, Seung-Hyeon Seok, Bong-Jun Jung, Seu-Na Lee, Dae-Won Sim, Min-Duk Seo
Publikováno v:
Crystals, Vol 8, Iss 2, p 97 (2018)
We report the crystal structure and bioinformatic analysis of SF173, a functionally uncharacterized protein from the human enteropathogenic bacteria Shigella flexneri. The structure shows a tightly interlinked dimer formed by adimeric core comprising
Externí odkaz:
https://doaj.org/article/43766f5d49b7449d8d07ffbcf84e9e76
Publikováno v:
Molecules, Vol 22, Iss 8, p 1347 (2017)
A large portion of proteins in living organisms are membrane proteins which play critical roles in the biology of the cell, from maintenance of the biological membrane integrity to communication of cells with their surroundings. To understand their m
Externí odkaz:
https://doaj.org/article/da4fdb3cf43f45409b3e5d6201c2de56
Autor:
Bokyeong Park, Sujin Lee, Yeontae Jang, Seu-Na Lee, Seungmi Kim, Jae-Sung Woo, Kyung Lib Jang, Jaekyung Hyun
Publikováno v:
BIODESIGN. 10:79-85
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2606
CRISPR-cas9-guided adenine base editors (ABEs) site-specifically convert the A-T base pair to G-C base pair in genomic DNA. The intracellular delivery of ABE proteins preassembled with guide RNAs (gRNAs) has shown greatly reduced off-target effects c
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628782
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5fb9b278badae0feb50d510a0f8bc5
https://doi.org/10.1007/978-1-0716-2879-9_10
https://doi.org/10.1007/978-1-0716-2879-9_10
Autor:
Jejoong Yoo, Hyeongseop Jeong, Hyung Jin Cha, Seu-Na Lee, Jae Sung Woo, Chang-Won Lee, Min Soo Kim, Hyuk-Joon Lee
Connexin family proteins assemble into hexameric hemichannels in a cell membrane, which dock together between two adjacent membranes to form gap junction intercellular channels (GJIChs). The most ubiquitously expressed connexin Cx43 plays important r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68fe88f856a62a37354ae962f8007ad
https://doi.org/10.21203/rs.3.rs-730129/v1
https://doi.org/10.21203/rs.3.rs-730129/v1
Autor:
Yohan Kim, Jihyeon Yu, Sung-Ah Hong, Jeongyun Eom, Kiseok Jang, Seu-Na Lee, Jae-Sung Woo, Jaemin Jeong, Sangsu Bae, Dongho Choi
SummaryDNA base editors and prime editing technology capable of therapeutic base conversion enable ex vivo gene editing therapy for various genetic diseases. For such therapy, it is critical that the target cells survive well both outside the body an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c123e61a3924cafd01cda6985c1292c
https://doi.org/10.1101/2020.09.14.297275
https://doi.org/10.1101/2020.09.14.297275
Autor:
Jae Sung Woo, Jeongyun Eom, Jaemin Jeong, Yohan Kim, Sung-Ah Hong, Jihyeon Yu, Sangsu Bae, Dongho Choi, Seu-Na Lee, Kiseok Jang
Publikováno v:
SSRN Electronic Journal.
DNA base editors and prime editing technology capable of therapeutic base conversion enable ex vivo gene editing therapy for various genetic diseases. For such therapy, it is critical that the target cells survive well both outside the body and after