Výsledky vyhledávání - "Settore MED/08

Updates on Lymphovascular Invasion in Breast Cancer

Autor: Elisabetta Kuhn, Donatella Gambini, Luca Despini, Dario Asnaghi, Letterio Runza, Stefano Ferrero

Traditionally, lymphovascular invasion (LVI) has represented one of the foremost pathological features of malignancy and has been associated with a worse prognosis in different cancers, including breast carcinoma. According to the most updated report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f61224bb1f6ca36000f0de03b20088f
https://hdl.handle.net/2434/961396

Zobrazit plný text záznamu

Analisi del trascrittoma nel trapianto di cuore: caratterizzazione e validazione dei profili di espressione genica come nuovo strumento e biomarcatore di accompagnamento per il monitoraggio

Autor: Giarraputo, Alessia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3657::58685f538683cfef058443e1f5f42b46
https://hdl.handle.net/11577/3474214

Zobrazit plný text záznamu

PD‐1‐induced T cell exhaustion is controlled by a Drp1‐dependent mechanism

Autor: Giuseppe Matarese, Biagio De Angelis, Valeria Cancila, Giorgia Scarpelli, Claudio Procaccini, Silvia Campello, Luca Simula, Claudio Tripodo, Alessandra Colamatteo, Simona Manni, Ylenia Antonucci, Concetta Quintarelli

Publikováno v: Molecular Oncology, Vol 16, Iss 1, Pp 188-205 (2022)
Molecular Oncology

Programmed cell death‐1 (PD‐1) signaling downregulates the T‐cell response, promoting an exhausted state in tumor‐infiltrating T cells, through mostly unveiled molecular mechanisms. Dynamin‐related protein‐1 (Drp1)‐dependent mitochondri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ca9f40c8f382ed460086062013790f
https://doaj.org/article/c6c81d19bafd46319ecd1f043d0fc599

Zobrazit plný text záznamu

Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer

Publikováno v: npj Breast Cancer, Vol 8, Iss 1, Pp 1-4 (2022)
NPJ Breast Cancer

The importance of integrating biomarkers into the TNM staging has been emphasized in the 8th Edition of the American Joint Committee on Cancer (AJCC) Staging system. In a pooled analysis of 2148 TNBC-patients in the adjuvant setting, TILs are found t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfe60deb498f368e054ad0151361005
https://doaj.org/article/1d7e042990e84c619c98e8ac72964f2e

Zobrazit plný text záznamu

CK2β-regulated signaling controls B cell differentiation and function

Publikováno v: Frontiers in Immunology. 13

Serine-Threonine kinase CK2 supports malignant B-lymphocyte growth but its role in B-cell development and activation is largely unknown. Here, we describe the first B-cell specific knockout (KO) mouse model of the β regulatory subunit of CK2. CK2βK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a124f5f41ebf392d0bda876b199bb43e
https://doi.org/10.3389/fimmu.2022.959138

Zobrazit plný text záznamu

SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the RNA virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Although SARS-CoV-2 was reported to alter several cellular pathways, its impact on DNA integrity and the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02232d4a62e92cbb07c5c2990aa00db5
https://hdl.handle.net/11577/3471427

Zobrazit plný text záznamu

The Defenders of the Alveolus Succumb in COVID-19 Pneumonia to SARS-CoV-2 and Necroptosis, Pyroptosis and Panoptosis

Autor: Luca Schifanella, Jodi Anderson, Garritt Wieking, Peter J Southern, Spinello Antinori, Massimo Galli, Mario Corbellino, Alessia Lai, Nichole Klatt, Timothy W Schacker, Ashley T Haase

Alveolar type II (ATII) pneumocytes as defenders of the alveolus are critical to repairing lung injury. We investigated the ATII reparative response in coronavirus disease 2019 (COVID-19) pneumonia, because the initial proliferation of ATII cells in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5a620396d27a0982e3c9c7fbccdd00
https://hdl.handle.net/2434/956978

Zobrazit plný text záznamu

Never stop wondering: When cells become PAP-art on the slides

Autor: Vittoria Lombardo, Stefania Cartesio, Guido Fadda, Esther Diana Rossi

The project named Victoria's cells was created to train health care personnel, especially in low-income countries. This innovative approach is designed to associate benign and malignant cellular images and/or patterns with a range of shapes and color

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ea9c919699c4561b3037b28595a200
https://hdl.handle.net/10807/227169

Zobrazit plný text záznamu

A conservative treatment for eosinophilic cystitis

Autor: Franco Alchiede Simonato, Nicola Pavan, Mirko Pinelli, Gabriele Tulone, Rosa Giaimo, Anna Martorana, Alchiede Simonato

Introduction: Eosinophilic cystitis is a rare condition which causes common symptoms and may mimic other conditions. Eosinophilic cystitis has several causes such as hypereosinophilic syndrome, inflammatory diseases, neoplasia, parasites or fungal in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af2102a7a56644b874fe25d32989f88
https://hdl.handle.net/10447/584271

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání