Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Setti G. Jagadeesh"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H1326-H1336
Recently, we reported that 11,12-epoxyeicosatrienoic acid (11,12-EET) potently activates rat mesenteric arterial ATP-sensitive K+ (KATP) channels and produces significant vasodilation through protein kinase A-dependent mechanisms. In this study, we t
Autor:
Setti G. Jagadeesh, John R. Falck, Liping Du, David L. Hachey, Valery Yermalitsky, Diane S. Keeney
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 316:371-379
The epidermis expresses cyclooxygenases, lipoxygenases, and cytochromes P450, which utilize arachidonic acid to generate a diverse array of lipid mediators affecting epidermal cellular differentiation and functions. Recent studies show that mouse epi
Publikováno v:
Hypertension. 42:555-561
Endothelium-dependent hyperpolarizations and relaxation of vascular smooth muscle induced by acetylcholine and bradykinin are mediated by endothelium-derived hyperpolarizing factors (EDHFs). In bovine coronary arteries, arachidonic acid metabolites,
Publikováno v:
Tetrahedron: Asymmetry. 16:1569-1571
The first enantioselective total synthesis of (-)-microbiotol and(+)-\beta-microbiotene, sesquiterpenes containing three neighboring quaternary carbon atoms belonging to the cyclocuparane group, starting from cyclogeraniol employing a Sharpless-Katsu
Autor:
Ishfaq A. Bukhari, William B. Campbell, Kathryn M. Gauthier, Bhavani Sangras, Setti G. Jagadeesh, John R. Falck
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 336(1)
Cytochrome P-450 epoxygenases metabolize arachidonic acid (AA) to epoxyeicosatrienoic acids (EETs). EETs relax vascular smooth muscle by membrane hyperpolarization. 14,15-Epoxyeicosa-5(Z)-enoic acid (14,15-EE5ZE) antagonizes many vascular actions of