Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Settapong T Kosiyatrakul"'
Autor:
Sana Ahmed-Seghir, Manisha Jalan, Helen E Grimsley, Aman Sharma, Shyam Twayana, Settapong T Kosiyatrakul, Christopher Thompson, Carl L Schildkraut, Simon N Powell
Publikováno v:
eLife, Vol 12 (2023)
When replication forks encounter DNA lesions that cause polymerase stalling, a checkpoint pathway is activated. The ATR-dependent intra-S checkpoint pathway mediates detection and processing of sites of replication fork stalling to maintain genomic i
Externí odkaz:
https://doaj.org/article/994d047302634e5f891f947f1a33a946
Autor:
Ruth B De-Paula, Advaitha Madireddy, Shyam Twayana, William C. Drosopoulos, Settapong T. Kosiyatrakul, Albino Bacolla, John A. Tainer, Eric E. Bouhassira, Angelica Barreto-Galvez, Carl L. Schildkraut
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Common fragile sites (CFSs) are normal loci that are genetically unstable under normal and oncogenic replication stress. Pol eta has been proposed to play a key role in CFS replication. Here, we show that in the absence of Pol eta, repli
Autor:
Settapong T. Kosiyatrakul, Paul M. Lieberman, Carl L. Schildkraut, William C. Drosopoulos, Zhong Deng, Shyam Twayana, Olga Vladimirova
Publikováno v:
Cell reports
SUMMARY The telomeric shelterin protein telomeric repeat-binding factor 2 (TRF2) recruits origin recognition complex (ORC) proteins, the foundational building blocks of DNA replication origins, to telomeres. We seek to determine whether TRF2-recruite
Publikováno v:
The Journal of Cell Biology
BLM helicase facilitates telomere replication by resolving G-quadruplex structures that can form in the G-rich repeats during leading strand synthesis.
Based on its in vitro unwinding activity on G-quadruplex (G4) DNA, the Bloom syndrome–assoc
Based on its in vitro unwinding activity on G-quadruplex (G4) DNA, the Bloom syndrome–assoc
Autor:
Susan B. Olson, María L. García-Rubio, Emilia Herrera-Moyano, Zi Yan, Carl L. Schildkraut, Nichole Owen, Jeannine Gerhardt, Elizabeth A Vuono, Niall G. Howlett, Advaitha Madireddy, Andrés Aguilera, Rebecca A. Boisvert, Settapong T. Kosiyatrakul
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Molecular Cell
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Cell
Digital.CSIC. Repositorio Institucional del CSIC
Madireddy, Advaitha et al.
Common fragile sites (CFSs) are genomic regions that are unstable under conditions of replicative stress. Although the characteristics of CFSs that render them vulnerable to stress are associated mainly with replicatio
Common fragile sites (CFSs) are genomic regions that are unstable under conditions of replicative stress. Although the characteristics of CFSs that render them vulnerable to stress are associated mainly with replicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2900dbf93919d6e051d25378625156a6
https://idus.us.es/handle/11441/67622
https://idus.us.es/handle/11441/67622
Autor:
C. David Allis, Christina M. Hughes, Settapong T. Kosiyatrakul, Steven Fiering, Paolo Norio, Carl L. Schildkraut, Zeqiang Guan, Eric E. Bouhassira, Ranjan Sen
Publikováno v:
The Journal of Cell Biology
Experimental attempts to activate replication origins within the temporal transition region in the IgH locus in mouse embryonic stem cells were not successful, and thus, why and how they become activated in B cells remains unclear.
In the mammal
In the mammal
Autor:
Carl L. Schildkraut, Michel G. Gauthier, John Bechhoefer, Meinrad Busslinger, Paolo Norio, Settapong T. Kosiyatrakul, Agnieszka Demczuk, Ingrid Veras
Publikováno v:
PLoS Biology
PLoS Biology, Vol 10, Iss 7, p e1001360 (2012)
PLoS Biology, Vol 10, Iss 7, p e1001360 (2012)
The temporal order of replication of mammalian chromosomes appears to be linked to their functional organization, but the process that establishes and modifies this order during cell differentiation remains largely unknown. Here, we studied how the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d569909d9525bd3265df31531c223d
http://summit.sfu.ca/item/13400
http://summit.sfu.ca/item/13400
Autor:
Subhash C. Verma, Qiliang Cai, Erle S. Robertson, Settapong T. Kosiyatrakul, Jie Lu, Maria E. McDowell, Carl L. Schildkraut
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002365 (2011)
PLoS Pathogens
PLoS Pathogens
Kaposi's sarcoma associated herpesvirus (KSHV), an etiologic agent of Kaposi's sarcoma, Body Cavity Based Lymphoma and Multicentric Castleman's Disease, establishes lifelong latency in infected cells. The KSHV genome tethers to the host chromosome wi
Autor:
Settapong T. Kosiyatrakul, Zi Yan, William C. Drosopoulos, Carl L. Schildkraut, Simone Guedes Calderano
Publikováno v:
The Journal of Cell Biology
Human telomere replication initiates either from within telomere repeats or from within the subtelomere using a chromosome-specific replication program that appears conserved between different cell types.
Telomeric and adjacent subtelomeric hete
Telomeric and adjacent subtelomeric hete
Autor:
Agnel Sfeir, Dirk Hockemeyer, Carl L. Schildkraut, Jan Karlseder, Settapong T. Kosiyatrakul, Titia de Lange, Sheila L. MacRae
Publikováno v:
Cell. (1):90-103
SummaryTelomeres protect chromosome ends through the interaction of telomeric repeats with shelterin, a protein complex that represses DNA damage signaling and DNA repair reactions. The telomeric repeats are maintained by telomerase, which solves the