Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Setsuro Fujii"'
Autor:
Yutaka Kojima, Mitsuru Hirohashi, Masaru Kido, Yoshihito Yamamoto, Setsuro Fujii, Koichiro Jitsukawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:1498-1506
The reactivities of 5-fluorouracil (5-FUra) degradation inhibitors, 2, 4- (2) and 2, 6-dihydroxypyridines (3), were investigated. Acylation of 2 and 2, 4-bis(trimethylsilyloxy)pyridines with equimolar amounts of acid chlorides preferentially occurred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4555d322754c80e5237ec819e9efb8f0
https://doi.org/10.1248/cpb.41.1498
https://doi.org/10.1248/cpb.41.1498
Autor:
Setsuro Fujii, Katsumasa Arakawa, Toyoo Nakayama, Hiroshi Ashizawa, Taira Seizo, Ikeda Masato, Minoru Oda
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:117-125
By developing 6-amidino-2-naphthyl 4-guanidinobenzoate (I, FUT-175) as a basic structure, its various derivatives were synthesized and their inhibitory activities on trypsin, plasmin, kallikrein, thrombin, C1r and C1s as well as on complement-mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db365d051aa59004e3b07638edfaa5bb
https://doi.org/10.1248/cpb.41.117
https://doi.org/10.1248/cpb.41.117
Autor:
Setsuro Fujii, Masaru Kido, Mitsuru Hirohashi, Yutaka Kojima, Yoshihito Yamamoto, Koichiro Jitsukawa
Publikováno v:
ChemInform. 25
The reactivities of 5-fluorouracil (5-FUra) degradation inhibitors, 2, 4- (2) and 2, 6-dihydroxypyridines (3), were investigated. Acylation of 2 and 2, 4-bis(trimethylsilyloxy)pyridines with equimolar amounts of acid chlorides preferentially occurred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0292c506b600b3316b8560a7aec41a49
https://doi.org/10.1002/chin.199421174
https://doi.org/10.1002/chin.199421174
Autor:
Minoru ODA, Yoshitaka INO, Kazunori NAKAMURA, Shigeru KURAMOTO, Kazunori SHIMAMURA, Masahiro IWAKI, Setsuro FUJII
Publikováno v:
Japanese Journal of Pharmacology. 52:23-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3721177a4460d9cd2191f4f8cebd04fb
https://doi.org/10.1016/s0021-5198(19)37764-9
https://doi.org/10.1016/s0021-5198(19)37764-9
Publikováno v:
Journal of pharmaceutical sciences. 85(7)
Two polymorphs (forms I and II) of lomeridine dihydrochloride (1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride) were prepared and characterized by means of X-ray powder diffractometry, infrared spectroscopy (IR), th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ecf85ff84c8b77e32d99542c5aca6a
https://pubmed.ncbi.nlm.nih.gov/8819003
https://pubmed.ncbi.nlm.nih.gov/8819003
Publikováno v:
Ensho. 1:367-375
Various cathepsins and other proteases such as plasmin, kallikrein, thrombin and C1 esterase in the exudate of experimental inflammation with croton oil or carageenan were examined.The existence of cathepsin D which causes accelration of vascular per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645ff467281b353d5f19d56338f9e3d8
https://doi.org/10.2492/jsir1981.1.3_367
https://doi.org/10.2492/jsir1981.1.3_367
Publikováno v:
The Journal of Biochemistry. 95:319-322
4-Substituted carbonylphenyl ester derivatives were prepared and their inhibitory effects on chymotrypsin, trypsin, thrombin, plasmin, pancreatic kallikrein, and plasma kallikrein were examined. Among the various inhibitors tested, 4-[2-(dimethylamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142e95a8edcd66b013267fb4a5a047d5
https://doi.org/10.1093/oxfordjournals.jbchem.a134611
https://doi.org/10.1093/oxfordjournals.jbchem.a134611
Publikováno v:
Agricultural and Biological Chemistry. 45:73-77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dd386bece99cb6a82b82eb327b59c29
https://doi.org/10.1080/00021369.1981.10864496
https://doi.org/10.1080/00021369.1981.10864496
Publikováno v:
Clinica Chimica Acta. 100:275-283
l -Prolyl- l -phenylalanyl- l -arginine-α-naphthylester (Pro-Phe-Arg-NE) was synthesized as a new substrate for use in the assay of kallikreins. An assay was developed based on the colorimetric determination of α-naphthol released by the enzyme rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98d1c8cf08492f8e68555687cd0cf12
https://doi.org/10.1016/0009-8981(80)90277-6
https://doi.org/10.1016/0009-8981(80)90277-6