Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Setsuro Fujii"'
Autor:
Yutaka Kojima, Mitsuru Hirohashi, Masaru Kido, Yoshihito Yamamoto, Setsuro Fujii, Koichiro Jitsukawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:1498-1506
The reactivities of 5-fluorouracil (5-FUra) degradation inhibitors, 2, 4- (2) and 2, 6-dihydroxypyridines (3), were investigated. Acylation of 2 and 2, 4-bis(trimethylsilyloxy)pyridines with equimolar amounts of acid chlorides preferentially occurred
Autor:
Setsuro Fujii, Katsumasa Arakawa, Toyoo Nakayama, Hiroshi Ashizawa, Taira Seizo, Ikeda Masato, Minoru Oda
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:117-125
By developing 6-amidino-2-naphthyl 4-guanidinobenzoate (I, FUT-175) as a basic structure, its various derivatives were synthesized and their inhibitory activities on trypsin, plasmin, kallikrein, thrombin, C1r and C1s as well as on complement-mediate
Autor:
Setsuro Fujii, Masaru Kido, Mitsuru Hirohashi, Yutaka Kojima, Yoshihito Yamamoto, Koichiro Jitsukawa
Publikováno v:
ChemInform. 25
The reactivities of 5-fluorouracil (5-FUra) degradation inhibitors, 2, 4- (2) and 2, 6-dihydroxypyridines (3), were investigated. Acylation of 2 and 2, 4-bis(trimethylsilyloxy)pyridines with equimolar amounts of acid chlorides preferentially occurred
Autor:
Minoru ODA, Yoshitaka INO, Kazunori NAKAMURA, Shigeru KURAMOTO, Kazunori SHIMAMURA, Masahiro IWAKI, Setsuro FUJII
Publikováno v:
Japanese Journal of Pharmacology. 52:23-34
Publikováno v:
Journal of pharmaceutical sciences. 85(7)
Two polymorphs (forms I and II) of lomeridine dihydrochloride (1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride) were prepared and characterized by means of X-ray powder diffractometry, infrared spectroscopy (IR), th
Autor:
Kazuo Ogawa, Hashimoto Sadao, Toshihiro Hamakawa, Yoshiyuki Muranaka, Setsuro Fujii, Tadafumi Terada
Publikováno v:
Chemical and Pharmaceutical Bulletin. 34:3252-3266
Many 2-oxoalkyl arenesulfonate derivatives having straight or branched alkyl chains of different lengths, 2-oxoalkyl bis-arenesulfonate derivatives, and alkyl arenesulfonate derivatives having a ketal moiety at the 2-position on the alkyl chain were
Publikováno v:
Journal of Pharmacy and Pharmacology. 37:545-549
FK-448 is a potent and specific inhibitor of chymotrypsin, which enhances the intestinal absorption of insulin in rats and dogs resulting in a decrease in blood glucose levels in these animals. In dogs, the immunoreactive insulin (IRI) level of plasm
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 614:501-510
Kallikrein (EC 3.4.21.8) was purified from rat stomach by column chromatography on p-aminobenzamidine-Sepharose, DEAE-Sephadex A-50 and Sephadex G-150 and by isoelectric focusing, measuring its activities to hydrolyse l-prolyl-l-phenylalanyl-l-argini
Publikováno v:
The Journal of Biochemistry. 75:131-137