Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Setsuo Funasaka"'
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
IC50 values for the inhibition of 93 human kinases by E7090.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727d71c17112f88bd1dc928969d95751
https://doi.org/10.1158/1535-7163.22506370
https://doi.org/10.1158/1535-7163.22506370
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
IC50 values for growth inhibition of various cancer cell lines by E7090.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9434018976082b47272abb5dd884b2ad
https://doi.org/10.1158/1535-7163.22506367.v1
https://doi.org/10.1158/1535-7163.22506367.v1
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
Western blot analysis of FGFR1 in human lung cancer cell lines harboring FGFR1 amplifications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0cbd7b4c4157ac6029645427248557
https://doi.org/10.1158/1535-7163.22506373
https://doi.org/10.1158/1535-7163.22506373
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
Kinome map of E7090. IC50 values of E7090 against wild-type kinases were used to create this kinome map. Illustration reproduced courtesy of Cell Signaling Technology, Inc. (www.cellsignal.com).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2d656250c492a35ac728aedeb86188
https://doi.org/10.1158/1535-7163.22506385.v1
https://doi.org/10.1158/1535-7163.22506385.v1
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
Inhibition of expression of proteins downstream of FGFR, including FRS2α, ERK, and AKT, in SNU-16 cells in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16959a4ad22ce9b683aa7de258513872
https://doi.org/10.1158/1535-7163.22506382.v1
https://doi.org/10.1158/1535-7163.22506382.v1
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
Western blot analysis of phospho-FGFR in SNU-16 tumors at the indicated times after treatment with the indicated concentrations of E7090. See also Figure 3D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3837318d6f6fb4676135aeb851ace703
https://doi.org/10.1158/1535-7163.22506379
https://doi.org/10.1158/1535-7163.22506379
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
siRNA knockdown experiment in 4T1 cells indicating that growth of 4T1 breast cancer cells depends on FGFR2 and FGFR3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2dbc3733eb685dbeabb5668e1fbec78
https://doi.org/10.1158/1535-7163.22506376.v1
https://doi.org/10.1158/1535-7163.22506376.v1
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
The FGFR signaling pathway has a crucial role in proliferation, survival, and migration of cancer cells, tumor angiogenesis, and drug resistance. FGFR genetic abnormalities, such as gene fusion, mutation, and amplification, have been implicated in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99edbb82e8632667d9aa9e5d5b108ead
https://doi.org/10.1158/1535-7163.c.6538381.v1
https://doi.org/10.1158/1535-7163.c.6538381.v1
Autor:
Akihiko Tsuruoka, Toshimitsu Uenaka, Masao Iwata, Junji Matsui, Tomohiro Matsushima, Toshimi Okada, Yoshinobu Yamane, Isao Ohashi, Yuki Karoji, Yusuke Nakatani, Yukinori Minoshima, Kiyoshi Okamoto, Naoko Hata Sugi, Satoshi Nagao, Setsuo Funasaka, Hiroko Kuramochi, Takayuki Nakagawa, Masaki Mikamoto, Yukiko Miyajima, Kotaro Kodama, Yuji Yamamoto, Saori Watanabe Miyano
Supplementary Table legends and Supplementary Figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c2fb8189ca1bb305f817e3eb3cfb0e
https://doi.org/10.1158/1535-7163.22506364.v1
https://doi.org/10.1158/1535-7163.22506364.v1
Autor:
Wei Li, Ying Cheng, Shude Cui, Tao Sun, Masahide Hiraiwa, Peng Yuan, Setsuo Funasaka, Kenichi Saito, Xichun Hu, Xiaojia Wang, Qingyuan Zhang, Binghe Xu, Zhendong Chen, Quchang Ouyang
Publikováno v:
European Journal of Cancer. 112:57-65
Introduction The objective of this study was to evaluate the efficacy and safety of eribulin monotherapy, relative to vinorelbine, in Chinese women with locally recurrent/metastatic breast cancer (MBC). Methods This phase III open-label, randomised,