Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Setsu Nakae"'
Autor:
Atsushi Hijikata, Clara Shionyu‐Mitsuyama, Setsu Nakae, Masafumi Shionyu, Motonori Ota, Shigehiko Kanaya, Takatsugu Hirokawa, Shogo Nakajima, Koichi Watashi, Tsuyoshi Shirai
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 285-294 (2022)
Cepharanthine (CEP) is a natural biscoclaurine alkaloid of plant origin and was recently demonstrated to have anti‐severe acute respiratory syndrome coronavirus 2 (anti‐SARS‐CoV‐2) activity. In this study, we evaluated whether natural analogu
Externí odkaz:
https://doaj.org/article/107db267d382427094cc9f1a9c93c0be
Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins
Autor:
Atsushi Hijikata, Clara Shionyu, Setsu Nakae, Masafumi Shionyu, Motonori Ota, Shigehiko Kanaya, Tsuyoshi Shirai
Publikováno v:
Biophysics and Physicobiology, Vol 18 (2021)
More than one and half years have passed, as of August 2021, since the COVID-19 caused by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of vaccine developments likely reduces the severe cases, there is still a stron
Externí odkaz:
https://doaj.org/article/f3e93de53051417d91e2241d78485984
Autor:
Yasuhiro Isogai, Hiroshi Imamura, Setsu Nakae, Tomonari Sumi, Ken-ichi Takahashi, Tsuyoshi Shirai
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102920- (2021)
Summary: Myoglobin (Mb) is highly concentrated in the myocytes of diving mammals such as whales and seals, in comparison with land animals, and its molecular evolution has played a crucial role in their deep-sea adaptation. We previously resurrected
Externí odkaz:
https://doaj.org/article/a44903b7182b4a65acca41d935cbd3bb
Publikováno v:
Biophysics and Physicobiology, Vol 16 (2019)
PolyADP-ribosylation (PARylation) is a posttranslational modification that is involved in the various cellular functions including DNA repair, genomic stability, and transcriptional regulation. PARylation is catalyzed by the poly(ADP-ribose) polymera
Externí odkaz:
https://doaj.org/article/ca1b3311633549819dbecafe9e1538b5
Autor:
Chieri Ida, Sachiko Yamashita, Takayuki Eguchi, Yasuhito Kuroda, Setsu Nakae, Yoshisuke Nishi, Kazuo Kamemura, Tsuyoshi Shirai, Tamio Mizukami, Masakazu Tanaka, Joel Moss, Masanao Miwa
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a6f9bfd92b3287dcbeaebe4d4ce4112
https://doi.org/10.1007/978-1-0716-2891-1_6
https://doi.org/10.1007/978-1-0716-2891-1_6
Autor:
Chieri, Ida, Sachiko, Yamashita, Takayuki, Eguchi, Yasuhito, Kuroda, Setsu, Nakae, Yoshisuke, Nishi, Kazuo, Kamemura, Tsuyoshi, Shirai, Tamio, Mizukami, Masakazu, Tanaka, Joel, Moss, Masanao, Miwa
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2609
PolyADP-ribosylation is a posttranslational modification of proteins that results from enzymatic synthesis of poly(ADP-ribose) with NAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::773ac7fce08075a526da59a444ec250c
https://pubmed.ncbi.nlm.nih.gov/36515831
https://pubmed.ncbi.nlm.nih.gov/36515831
Autor:
Motonori Ota, Clara Shionyu-Mitsuyama, Masafumi Shionyu, Shigehiko Kanaya, Atsushi Hijikata, Setsu Nakae, Tsuyoshi Shirai
Publikováno v:
FEBS Letters
Febs Letters
Febs Letters
The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) caused by the novel coronavirus SARS-CoV-2 a pandemic. There is, however, no confirmed anti-COVID-19 therapeutic currently. In order to assist structure-based di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65067f9d4d1cc8448514d41692b7a2ac
https://doi.org/10.1002/1873-3468.13806
https://doi.org/10.1002/1873-3468.13806
Autor:
Ikuo Fujii, Tsuyoshi Shirai, Toshiji Tada, Setsu Nakae, Masaaki Sawa, Daisuke Fujiwara, Maho Kitamura
Publikováno v:
Acta Crystallogr F Struct Biol Commun
Eukaryotic protein kinases contain an Asp-Phe-Gly (DFG) motif, the conformation of which is involved in controlling the catalytic activity, at the N-terminus of the activation segment. The motif can be switched between active-state (DFG-in) and inact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7189c02d124903866ecd7f83d09e30a4
https://europepmc.org/articles/PMC8647213/
https://europepmc.org/articles/PMC8647213/
Autor:
Clara Shionyu-Mitsuyama, Takatsugu Hirokawa, Atsushi Hijikata, Tsuyoshi Shirai, Setsu Nakae, Motonori Ota, Koichi Watashi, Masafumi Shionyu, Shogo Nakajima, Shigehiko Kanaya
Cepharanthine is a natural of plant origin, and recently demonstrated to have anti-SARS-CoV-2 activity. In order to evaluate the other natural analogues as a potential COVID-19 drug, a total of 24 compounds resembling cepharanthine were extracted fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::679d53955c1d089597586f3fd1ffb4fc
https://doi.org/10.33774/chemrxiv-2021-mcf3k
https://doi.org/10.33774/chemrxiv-2021-mcf3k
Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins
Autor:
Masafumi Shionyu, Shigehiko Kanaya, Clara Shionyu, Motonori Ota, Setsu Nakae, Atsushi Hijikata, Tsuyoshi Shirai
Publikováno v:
Biophysics and Physicobiology, Vol 18 (2021)
Biophysics and Physicobiology
Biophysics and Physicobiology
More than one and half years have passed, as of August 2021, since the COVID-19 caused by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of vaccine developments likely reduces the severe cases, there is still a stron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c9c7aba9d79135cd0c7e3e37663651
https://doaj.org/article/f3e93de53051417d91e2241d78485984
https://doaj.org/article/f3e93de53051417d91e2241d78485984