Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases

Autor: Yadav, Rajbharan, Sukumaran, Siddharth, Lutman, Jeff, Mitra, Mayur S., Halpern, Wendy, Sun, Tianhe, Setiadi, A. Francesca, Neighbors, Margaret, Sheng, X. Rebecca, Yip, Victor, Shen, Ben-Quan, Liu, Chang, Han, Lyrialle, Ovacik, Ayse Meric, Wu, Yan, Glickstein, Sara, Kunder, Rebecca, Arron, Joseph R., Pan, Lin, Kamath, Amrita V., Stefanich, Eric G.

Publikováno v: In Journal of Pharmaceutical Sciences November 2023 112(11):2910-2920

The Development and Characterization of a Highly Sensitive Mature TGFβ3 Assay to Evaluate Anti-TGFβ3 Target Engagement.

Autor: Setiadi, A. Francesca, Sperinde, Gizette, Cheu, Melissa, Liang, Wei-Ching, Lin, WeiYu, Mahood, Connie, Fischer, Saloumeh K.

Publikováno v: AAPS Journal; Feb2023, Vol. 25 Issue 1, p1-11, 11p

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

Autor: Humby, Frances, Lewis, Myles, Ramamoorthi, Nandhini, Hackney, Jason A, Barnes, Michael R, Bombardieri, Michele, Setiadi, A. Francesca, Kelly, Stephen, Bene, Fabiola, DiCicco, Maria, Riahi, Sudeh, Rocher, Vidalba, Ng, Nora, Lazarou, Ilias, Hands, Rebecca, van der Heijde, Désirée, Landewé, Robert B M, van der Helm-van Mil, Annette, Cauli, Alberto, McInnes, Iain, Buckley, Christopher Dominic, Choy, Ernest H, Taylor, Peter C, Townsend, Michael J, Pitzalis, Costantino

Publikováno v: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 78(6), 761-772
Annals of the rheumatic diseases, 78(6), 761-772. BMJ Publishing Group

Objectives To unravel the hierarchy of cellular/molecular pathways in the disease tissue of early, treatment-naïve rheumatoid arthritis (RA) patients and determine their relationship with clinical phenotypes and treatment response/outcomes longitudi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b8e56b4baddc9740ce37db0b753216f3
https://doi.org/10.1136/annrheumdis-2018-214539

CD138-negative plasma cell myeloma: a diagnostic challenge and a unique entity.

Autor: Setiadi, Audi Francesca, Yuri Sheikine

Publikováno v: BMJ Case Reports; 12/1/2019, Vol. 12 Issue 12, p1-4, 4p, 1 Color Photograph, 1 Graph

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