Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Seth P. Miller"'
Publikováno v:
ACS Central Science, Vol 4, Iss 1, Pp 71-80 (2017)
The KRAS gene encodes two isoforms, KRas4a and KRas4b. Differences in the signaling functions of the two KRas proteins are poorly understood. Here we report the comparative and nucleotide-dependent interactomes of KRas4a and KRas4b. Many previously u
Externí odkaz:
https://doaj.org/article/4bb96cfea1bc48e89fe0b84aa44e06ea
Autor:
Michael L. DeKay, Dan R. Schley, Seth A. Miller, Breann M. Erford, Jonghun Sun, Michael N. Karim, Mandy B. Lanyon
Publikováno v:
Judgment and Decision Making, Vol 11, Pp 361-379 (2016)
People often make more rational choices between monetary prospects when their choices will be played out many times rather than just once. For example, previous research has shown that the certainty effect and the possibility effect (two common-ratio
Externí odkaz:
https://doaj.org/article/102c83dc2629453eb21a081775b7cdd3
Publikováno v:
Judgment and Decision Making, Vol 8, Pp 662-677 (2013)
The emergence of a leading alternative during the course of a decision is known to bias the evaluation of new information in a manner that favors that alternative. We report 3 studies that address the sensitivity of predecisional information distorti
Externí odkaz:
https://doaj.org/article/85ffefd02a3e4597a69d8f056d5a6b87
Autor:
Seth P. Miller, George Maio, Xiaoyu Zhang, Felix S. Badillo Soto, Julia Zhu, Stephen Z. Ramirez, Hening Lin
Publikováno v:
Molecularcellular proteomics : MCP. 21(8)
Active mutations in the RAS genes are found in ∼30% of human cancers. Although thought to have overlapping functions, RAS isoforms show preferential activation in human tumors, which prompted us to employ a comparative and quantitative proteomics a
Publikováno v:
ACS Chem Biol
Mammalian histone deacetylases (HDACs) are a class of enzymes that play important roles in biological pathways. Existing HDAC inhibitors target multiple HDACs without much selectivity. Inhibitors that target one particular HDAC will be useful for inv
Autor:
Hening Lin, Seth P. Miller, Pornpun Aramsangtienchai, Bin He, Lunzhi Dai, Yingming Zhao, Nicole A Spiegelman
Publikováno v:
ACS chemical biology. 11(10)
The histone deacetylase (HDAC) family regulates many biological pathways through the deacetylation of lysine residues on histone and nonhistone proteins. Mammals have 18 HDACs that are classified into four classes. Class I, II, and IV are zinc-depend
Publikováno v:
Frontiers in Marine Science, Vol 5 (2018)
Planktonic larvae are thought to be very susceptible to offshore advection in upwelling regimes, increasing dispersal and decreasing recruitment. However, larvae of 42 species of nearshore benthic crustaceans primarily developed on the inner shelf at
Externí odkaz:
https://doaj.org/article/5b052ded271c410ea200e7ce209e67d2
Autor:
Denise L. Breitburg, Joseph Salisbury, Joan M. Bernhard, Wei-Jun Cai, Sam Dupont, Scott C. Doney, Kristy J. Kroeker, Lisa A. Levin, W. Christopher Long, Lisa M. Milke, Seth H. Miller, Beth Phelan, Uta Passow, Brad A. Seibel, Anne E. Todgham, Ann M. Tarrant
Publikováno v:
Oceanography, Vol 28, Iss 2, Pp 48-61 (2015)
Oceanic and coastal waters are acidifying due to processes dominated in the open ocean by increasing atmospheric CO2 and dominated in estuaries and some coastal waters by nutrient-fueled respiration. The patterns and severity of acidification, as wel
Externí odkaz:
https://doaj.org/article/2d5291f26f2b49828d92f7122d210296
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109167 (2014)
Future climate change is predicted to alter the physical characteristics of oceans and estuaries, including pH, temperature, oxygen, and salinity. Investigating how species react to the influence of such multiple stressors is crucial for assessing ho
Externí odkaz:
https://doaj.org/article/68feea156ea541648752f09a3b063673
Autor:
Kristy J Kroeker, Brian Gaylord, Tessa M Hill, Jessica D Hosfelt, Seth H Miller, Eric Sanford
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100353 (2014)
Ocean acidification (OA) is occurring across a backdrop of concurrent environmental changes that may in turn influence species' responses to OA. Temperature affects many fundamental biological processes and governs key reactions in the seawater carbo
Externí odkaz:
https://doaj.org/article/313a700ba3814e35a1ce2d518b743fad