Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Seth M. Dever"'
Autor:
Myosotys Rodriguez, Jessica Lapierre, Chet Raj Ojha, Ajeet Kaushik, Elena Batrakova, Fatah Kashanchi, Seth M. Dever, Madhavan Nair, Nazira El-Hage
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract We previously reported that activation of the host autophagic protein, Beclin1, by HIV-1 infection represents an essential mechanism in controlling HIV replication and viral-induced inflammatory responses in microglial cells. Existing antire
Externí odkaz:
https://doaj.org/article/1d8ea56384f5479588de2d484e112d81
Autor:
Myosotys Rodriguez, Jessica Lapierre, Chet Raj Ojha, Ajeet Kaushik, Elena Batrakova, Fatah Kashanchi, Seth M. Dever, Madhavan Nair, Nazira El-Hage
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Externí odkaz:
https://doaj.org/article/f398c0ab6b73415dbbc3b72fbd6b8293
Autor:
Myosotys Rodriguez, Jessica Lapierre, Chet Raj Ojha, Hary Estrada-Bueno, Seth M. Dever, David A. Gewirtz, Fatah Kashanchi, Nazira El-Hage
Publikováno v:
Viruses, Vol 9, Iss 8, p 201 (2017)
Under physiological conditions, the function of astrocytes in providing brain metabolic support is compromised under pathophysiological conditions caused by human immunodeficiency virus (HIV) and opioids. Herein, we examined the role of autophagy, a
Externí odkaz:
https://doaj.org/article/7471fe6124454668b0bb25b15df48545
Autor:
Chet Raj Ojha, Jessica Lapierre, Myosotys Rodriguez, Seth M. Dever, Mohammad Asad Zadeh, Catherine DeMarino, Michelle L. Pleet, Fatah Kashanchi, Nazira El-Hage
Publikováno v:
Viruses, Vol 9, Iss 7, p 176 (2017)
The autophagy–lysosomal pathway mediates a degradative process critical in the maintenance of cellular homeostasis as well as the preservation of proper organelle function by selective removal of damaged proteins and organelles. In some situations,
Externí odkaz:
https://doaj.org/article/35ba29160c9a4fdd8e4ec1cca80660ca
Publikováno v:
Journal of Virological Methods. 224:20-29
HIV penetrates the central nervous system (CNS), and although it is clear that microglia and to a lesser extent astrocytes are infected, whether certain other cell types such as neurons are infected remains unclear. Here, we confirmed the finding tha
Autor:
Elena V. Batrakova, Jessica Lapierre, Fatah Kashanchi, Myosotys Rodriguez, Nazira El-Hage, Seth M. Dever, Chet Raj Ojha, Ajeet Kaushik, Madhavan Nair
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
We previously reported that activation of the host autophagic protein, Beclin1, by HIV-1 infection represents an essential mechanism in controlling HIV replication and viral-induced inflammatory responses in microglial cells. Existing antiretroviral
Autor:
Nisha Gnawali, Lawrence F. Povirk, Kristoffer Valerie, Sarah E. Golding, Aarthi Narayanan, Kylene Kehn-Hall, Bo Xu, Ashraf Khalil, Seth M. Dever, Jason M. Beckta, Amrita Sule, Elizabeth Rosenberg
Publikováno v:
Oncotarget
// Jason M. Beckta 1, 2, * , Seth M. Dever 1, 2, * , Nisha Gnawali 1 , Ashraf Khalil 1 , Amrita Sule 1, 2 , Sarah E. Golding 1 , Elizabeth Rosenberg 1 , Aarthi Narayanan 3 , Kylene Kehn-Hall 3 , Bo Xu 4 , Lawrence F. Povirk 5 , Kristoffer Valerie 1,
Autor:
David A. Gewirtz, Myosotys Rodriguez, Nazira El-Hage, John J. Shacka, Ruturaj R. Masvekar, Seth M. Dever
Publikováno v:
Journal of Virology. 89:1024-1035
Microglia are the predominant resident central nervous system (CNS) cell type productively infected by HIV-1, and play a key role in the progression of HIV-associated dementia (HAD). Moreover, neural dysfunction and progression to HAD are accelerated
Autor:
Fatah Kashanchi, Nazira El-Hage, Mohammad Asad Zadeh, Myosotys Rodriguez, Catherine DeMarino, Jessica Lapierre, Michelle L. Pleet, Seth M. Dever, Chet Raj Ojha
Publikováno v:
Viruses
Viruses, Vol 9, Iss 7, p 176 (2017)
Viruses, Vol 9, Iss 7, p 176 (2017)
The autophagy-lysosomal pathway mediates a degradative process critical in the maintenance of cellular homeostasis as well as the preservation of proper organelle function by selective removal of damaged proteins and organelles. In some situations, c
Autor:
Seth M. Dever, Myosotys Rodriguez, Chet Raj Ojha, Jessica Lapierre, Nazira El-Hage, David A. Gewirtz, Hary Estrada-Bueno, Fatah Kashanchi
Publikováno v:
Viruses, Vol 9, Iss 8, p 201 (2017)
Viruses; Volume 9; Issue 8; Pages: 201
Viruses
Viruses; Volume 9; Issue 8; Pages: 201
Viruses
Under physiological conditions, the function of astrocytes in providing brain metabolic support is compromised under pathophysiological conditions caused by human immunodeficiency virus (HIV) and opioids. Herein, we examined the role of autophagy, a