Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Seth M, Weinberg"'
Autor:
Anthony M. Musolf, Cristina M. Justice, Zeynep Erdogan-Yildirim, Seppe Goovaerts, Araceli Cuellar, John R. Shaffer, Mary L. Marazita, Peter Claes, Seth M. Weinberg, Jae Li, Craig Senders, Marike Zwienenberg, Emil Simeonov, Radka Kaneva, Tony Roscioli, Lorena Di Pietro, Marta Barba, Wanda Lattanzi, Michael L. Cunningham, Paul A. Romitti, Simeon A. Boyadjiev
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Craniosynostosis (CS) is a major birth defect resulting from premature fusion of cranial sutures. Nonsyndromic CS occurs more frequently than syndromic CS, with sagittal nonsyndromic craniosynostosis (sNCS) presenting as the most common CS p
Externí odkaz:
https://doaj.org/article/f648374bc2b0416ab9f8c6846eee6350
Autor:
Yulin Dai, Toshiyuki Itai, Guangsheng Pei, Fangfang Yan, Yan Chu, Xiaoqian Jiang, Seth M. Weinberg, Nandita Mukhopadhyay, Mary L. Marazita, Lukas M. Simon, Peilin Jia, Zhongming Zhao
Publikováno v:
HGG Advances, Vol 5, Iss 3, Pp 100312- (2024)
Summary: Orofacial clefts (OFCs) are among the most common human congenital birth defects. Previous multiethnic studies have identified dozens of associated loci for both cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP). Alth
Externí odkaz:
https://doaj.org/article/1674e572859a430fb03d3eef41dde83f
Autor:
Seppe Goovaerts, Hanne Hoskens, Ryan J. Eller, Noah Herrick, Anthony M. Musolf, Cristina M. Justice, Meng Yuan, Sahin Naqvi, Myoung Keun Lee, Dirk Vandermeulen, Heather L. Szabo-Rogers, Paul A. Romitti, Simeon A. Boyadjiev, Mary L. Marazita, John R. Shaffer, Mark D. Shriver, Joanna Wysocka, Susan Walsh, Seth M. Weinberg, Peter Claes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract The cranial vault in humans is highly variable, clinically relevant, and heritable, yet its genetic architecture remains poorly understood. Here, we conduct a joint multi-ancestry and admixed multivariate genome-wide association study on 3D
Externí odkaz:
https://doaj.org/article/69a3d3cc3f27415f9870d75eead756a6
Autor:
Jaaved Mohammed, Neha Arora, Harold S Matthews, Karissa Hansen, Maram Bader, Susan Walsh, John R Shaffer, Seth M Weinberg, Tomek Swigut, Peter Claes, Licia Selleri, Joanna Wysocka
Publikováno v:
eLife, Vol 13 (2024)
Genome-wide association studies (GWAS) identified thousands of genetic variants linked to phenotypic traits and disease risk. However, mechanistic understanding of how GWAS variants influence complex morphological traits and can, in certain cases, si
Externí odkaz:
https://doaj.org/article/2cc1a2d4cf454d649f23f3d5f8c28b50
Autor:
Zuqi Li, Federico Melograna, Hanne Hoskens, Diane Duroux, Mary L. Marazita, Susan Walsh, Seth M. Weinberg, Mark D. Shriver, Bertram Müller-Myhsok, Peter Claes, Kristel Van Steen
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Multi-view data offer advantages over single-view data for characterizing individuals, which is crucial in precision medicine toward personalized prevention, diagnosis, or treatment follow-up.Methods: Here, we develop a network-guided m
Externí odkaz:
https://doaj.org/article/01f1dc8fd9614fd58c2406d60526e091
Autor:
Kelsey Robinson, Trenell J. Mosley, Kenneth S. Rivera-González, Christopher R. Jabbarpour, Sarah W. Curtis, Wasiu Lanre Adeyemo, Terri H. Beaty, Azeez Butali, Carmen J. Buxó, David J. Cutler, Michael P. Epstein, Lord J.J. Gowans, Jacqueline T. Hecht, Jeffrey C. Murray, Gary M. Shaw, Lina Moreno Uribe, Seth M. Weinberg, Harrison Brand, Mary L. Marazita, Robert J. Lipinski, Elizabeth J. Leslie
Publikováno v:
HGG Advances, Vol 4, Iss 4, Pp 100234- (2023)
Summary: Cleft palate (CP) is one of the most common craniofacial birth defects; however, there are relatively few established genetic risk factors associated with its occurrence despite high heritability. Historically, CP has been studied as a singl
Externí odkaz:
https://doaj.org/article/d701a794d6d64abda81ebac6e8be9898
Autor:
Franziska Wilke, Noah Herrick, Harold Matthews, Hanne Hoskens, Sylvia Singh, John R. Shaffer, Seth M. Weinberg, Mark D. Shriver, Peter Claes, Susan Walsh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Facial ancestry can be described as variation that exists in facial features that are shared amongst members of a population due to environmental and genetic effects. Even within Europe, faces vary among subregions and may lead to confoundin
Externí odkaz:
https://doaj.org/article/563b8273693847c8a42465d2fc1667be
Autor:
Ronilo Ragodos, Tong Wang, Carmencita Padilla, Jacqueline T. Hecht, Fernando A. Poletta, Iêda M. Orioli, Carmen J. Buxó, Azeez Butali, Consuelo Valencia-Ramirez, Claudia Restrepo Muñeton, George L. Wehby, Seth M. Weinberg, Mary L. Marazita, Lina M. Moreno Uribe, Brian J. Howe
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Children with orofacial clefting (OFC) present with a wide range of dental anomalies. Identifying these anomalies is vital to understand their etiology and to discern the complex phenotypic spectrum of OFC. Such anomalies are currently ident
Externí odkaz:
https://doaj.org/article/3800fcecdedd481ebcf9fe8c511f1042
Autor:
Rasha N. Alotaibi, Brian J. Howe, Jonathan M. Chernus, Nandita Mukhopadhyay, Carla Sanchez, Frederic W. B. Deleyiannis, Katherine Neiswanger, Carmencita Padilla, Fernando A. Poletta, Ieda M. Orioli, Carmen J. Buxó, Jacqueline T. Hecht, George L. Wehby, Ross E. Long, Alexandre R. Vieira, Seth M. Weinberg, John R. Shaffer, Lina M. Moreno Uribe, Mary L. Marazita
Publikováno v:
BMC Oral Health, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Dental caries is one of the most common chronic diseases and is influenced by a complex interplay of genetic and environmental factors. Most previous genetic studies of caries have focused on identifying genes that contribute to d
Externí odkaz:
https://doaj.org/article/7e1cb49b8d3c4ae58f9dc61b99d267ba
Autor:
Harold S. Matthews, Richard L. Palmer, Gareth S. Baynam, Oliver W. Quarrell, Ophir D. Klein, Richard A. Spritz, Raoul C. Hennekam, Susan Walsh, Mark Shriver, Seth M. Weinberg, Benedikt Hallgrimsson, Peter Hammond, Anthony J. Penington, Hilde Peeters, Peter D. Claes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Craniofacial dysmorphism is associated with thousands of genetic and environmental disorders. Delineation of salient facial characteristics can guide clinicians towards a correct clinical diagnosis and understanding the pathogenesis of the d
Externí odkaz:
https://doaj.org/article/9ea19e482b9a40fb850f0d90987b746d