Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Seth Haney"'
Autor:
Jennie S. Lavine, Anthony D. Scotina, Seth Haney, Jessie P. Bakker, Elena S. Izmailova, Larsson Omberg
Publikováno v:
Frontiers in Digital Health, Vol 6 (2024)
IntroductionParkinson's Disease affects over 8.5 million people and there are currently no medications approved to treat underlying disease. Clinical trials for disease modifying therapies (DMT) are hampered by a lack of sufficiently sensitive measur
Externí odkaz:
https://doaj.org/article/d65414c98f3d486591f5c240318e8861
Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality
Autor:
Brian Kim, Seth Haney, Ana P Milan, Shruti Joshi, Zane Aldworth, Nikolai Rulkov, Alexander T Kim, Maxim Bazhenov, Mark A Stopfer
Publikováno v:
eLife, Vol 12 (2023)
Odorants binding to olfactory receptor neurons (ORNs) trigger bursts of action potentials, providing the brain with its only experience of the olfactory environment. Our recordings made in vivo from locust ORNs showed that odor-elicited firing patter
Externí odkaz:
https://doaj.org/article/35273e50c95843e7a60d57bb991cd1c6
Autor:
Hong Lei, Seth Haney, Christopher M Jernigan, Xiaojiao Guo, Chelsea N Cook, Maxim Bazhenov, Brian H Smith
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265009 (2022)
Animals are constantly bombarded with stimuli, which presents a fundamental problem of sorting among pervasive uninformative stimuli and novel, possibly meaningful stimuli. We evaluated novelty detection behaviorally in honey bees as they position th
Externí odkaz:
https://doaj.org/article/e4895033682e4cfeaa8b5ae1656b7dfc
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 5, p e1006131 (2018)
Many tumors are characterized by genetic instability, producing an assortment of genetic variants of tumor cells called subclones. These tumors and their surrounding environments form complex multi-cellular ecosystems, where subclones compete for res
Externí odkaz:
https://doaj.org/article/c58b7352d59a494ea4a5dd733b38b2ba
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 4, p e1000062 (2008)
Neural circuits exploit numerous strategies for encoding information. Although the functional significance of individual coding mechanisms has been investigated, ways in which multiple mechanisms interact and integrate are not well understood. The lo
Externí odkaz:
https://doaj.org/article/69e2572dc6b24dfa84b04be50b0e1e8e
Autor:
Hong Lei, Seth Haney, Christopher M. Jernigan, Xiaojiao Guo, Chelsea N. Cook, Maxim Bazhenov, Brian H. Smith
Publikováno v:
PloS one. 17(3)
Animals are constantly bombarded with stimuli, which presents a fundamental problem of sorting among pervasive uninformative stimuli and novel, possibly meaningful stimuli. We evaluated novelty detection behaviorally in honey bees as they position th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83436384dd70e456992035d309a1be45
https://pubmed.ncbi.nlm.nih.gov/35353837
https://pubmed.ncbi.nlm.nih.gov/35353837
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 5, p e1006131 (2018)
PLoS Computational Biology
PLoS Computational Biology
Many tumors are characterized by genetic instability, producing an assortment of genetic variants of tumor cells called subclones. These tumors and their surrounding environments form complex multi-cellular ecosystems, where subclones compete for res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4b492c340c455b869ff131dc34bbae
http://europepmc.org/articles/PMC5991406?pdf=render
http://europepmc.org/articles/PMC5991406?pdf=render
Publikováno v:
Journal of neurophysiology. 120(1)
Adaptation of neural responses is ubiquitous in sensory systems and can potentially facilitate many important computational functions. Here we examined this issue with a well-constrained computational model of the early olfactory circuits. In the ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882a36239ca22544b83cd6fc4e58e84a
https://pubmed.ncbi.nlm.nih.gov/29589811
https://pubmed.ncbi.nlm.nih.gov/29589811
Publikováno v:
Haney, Seth; Bardwell, Lee; & Nie, Qing. (2010). Ultrasensitive responses and specificity in cell signaling. BMC Systems Biology, 4(1), 119. doi: http://dx.doi.org/10.1186/1752-0509-4-119. Retrieved from: http://www.escholarship.org/uc/item/9m257780
BMC Systems Biology
BMC Systems Biology, Vol 4, Iss 1, p 119 (2010)
Haney, Seth; Bardwell, Lee; & Nie, Qing. (2010). Ultrasensitive Responses and Specificity in Cell Signaling. BMC Systems Biology, 4(1), 119. doi: 10.1186/1752-0509-4-119. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/47b8k64v
BMC Systems Biology
BMC Systems Biology, Vol 4, Iss 1, p 119 (2010)
Haney, Seth; Bardwell, Lee; & Nie, Qing. (2010). Ultrasensitive Responses and Specificity in Cell Signaling. BMC Systems Biology, 4(1), 119. doi: 10.1186/1752-0509-4-119. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/47b8k64v
Background Interconnected cell signaling pathways are able to efficiently and accurately transmit a multitude of different signals, despite an inherent potential for undesirable levels of cross-talk. To ensure that an appropriate response is produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52c1f23d2a67a07676fbc1e1e0822ff
http://www.escholarship.org/uc/item/9m257780
http://www.escholarship.org/uc/item/9m257780
