Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Seth G.N. Grant"'
Autor:
Ana Gutierrez del Arroyo, Anna Hadjihambi, Jenifer Sanchez, Egor Turovsky, Vitaly Kasymov, David Cain, Tom D. Nightingale, Simon Lambden, Seth G.N. Grant, Alexander V. Gourine, Gareth L. Ackland
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 457-469 (2019)
Background: Neutrophil depletion improves neurologic outcomes in experimental sepsis/brain injury. We hypothesized that neutrophils may exacerbate neuronal injury through the release of neurotoxic quantities of the neurotransmitter glutamate. Methods
Externí odkaz:
https://doaj.org/article/0aaa2e17d6344966b236b4d45e768b8f
Autor:
Esperanza Fernández, Mark O. Collins, René A.W. Frank, Fei Zhu, Maksym V. Kopanitsa, Jess Nithianantharajah, Sarah A. Lemprière, David Fricker, Kathryn A. Elsegood, Catherine L. McLaughlin, Mike D.R. Croning, Colin Mclean, J. Douglas Armstrong, W. David Hill, Ian J. Deary, Giulia Cencelli, Claudia Bagni, Menachem Fromer, Shaun M. Purcell, Andrew J. Pocklington, Jyoti S. Choudhary, Noboru H. Komiyama, Seth G.N. Grant
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 679-691 (2017)
Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition. We applied an integrated proteomic and genetic strategy by targeting a tandem af
Externí odkaz:
https://doaj.org/article/75279cd7ad9f46f593bed20c4b72bd92
Autor:
Sean McKay, Tomás J. Ryan, Jamie McQueen, Tim Indersmitten, Katie F.M. Marwick, Philip Hasel, Maksym V. Kopanitsa, Paul S. Baxter, Marc-André Martel, Peter C. Kind, David J.A. Wyllie, Thomas J. O’Dell, Seth G.N. Grant, Giles E. Hardingham, Noboru H. Komiyama
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 841-851.e4 (2018)
Summary: The GluN2 subtype (2A versus 2B) determines biophysical properties and signaling of forebrain NMDA receptors (NMDARs). During development, GluN2A becomes incorporated into previously GluN2B-dominated NMDARs. This “switch” is proposed to
Externí odkaz:
https://doaj.org/article/dd3ab73865074c9fa7090b212b99cf6f
Autor:
Edita Bulovaite, Zhen Qiu, Maximilian Kratschke, Adrianna Zgraj, David G. Fricker, Eleanor J. Tuck, Ragini Gokhale, Babis Koniaris, Shekib A. Jami, Paula Merino-Serrais, Elodie Husi, Lorena Mendive-Tapia, Marc Vendrell, Thomas J. O’Dell, Javier DeFelipe, Noboru H. Komiyama, Anthony Holtmaat, Erik Fransén, Seth G.N. Grant
Publikováno v:
Neuron
Bulovaite, E, Qiu, Z, Kratschke, M, Zgraj, A, Fricker, D G, Tuck, E J, Gokhale, R, Koniaris, B, Jami, S A, Merino-Serrais, P, Husi, E, Mendive-Tapia, L, Vendrell, M, O'Dell, T J, DeFelipe, J, Komiyama, N H, Holtmaat, A, Fransén, E & Grant, S G N 2022, ' A brain atlas of synapse protein lifetime across the mouse lifespan ', Neuron . https://doi.org/10.1016/j.neuron.2022.09.009
Bulovaite, E, Qiu, Z, Kratschke, M, Zgraj, A, Fricker, D G, Tuck, E J, Gokhale, R, Koniaris, B, Jami, S A, Merino-Serrais, P, Husi, E, Mendive-Tapia, L, Vendrell, M, O'Dell, T J, DeFelipe, J, Komiyama, N H, Holtmaat, A, Fransén, E & Grant, S G N 2022, ' A brain atlas of synapse protein lifetime across the mouse lifespan ', Neuron . https://doi.org/10.1016/j.neuron.2022.09.009
The lifetime of proteins in synapses is important for their signaling, maintenance, and remodeling, and for memory duration. We quantified the lifetime of endogenous PSD95, an abundant postsynaptic protein in excitatory synapses, at single-synapse re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ab62ef318976a1b25f15c5b508a7f7
http://hdl.handle.net/10261/305259
http://hdl.handle.net/10261/305259
Autor:
Laura Tomas-Roca, Zhen Qiu, Erik Fransén, Ragini Gokhale, Edita Bulovaite, David J. Price, Noboru H. Komiyama, Seth G.N. Grant
Neurodevelopmental disorders of genetic origin delay the acquisition of normal abilities and cause disabling phenotypes. Spontaneous attenuation and even complete amelioration of symptoms in early childhood and adolescence occur in many disorders1–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::564c005b0b6c0ea3b48191e4bfe832d7
https://doi.org/10.1101/2021.12.21.473638
https://doi.org/10.1101/2021.12.21.473638
Publikováno v:
Neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::c515a76f83fa5ed35cf806c7e314fd95
Autor:
Stephanie A. Barnes, Silvia Bassani, Àlex Bayés, Elizabeth Berry-Kravis, Luigi Boccuto, Thomas Bourgeron, Jamel Chelly, Bice Chini, Jérôme Ezan, Jozef Gecz, Valentina Gigliucci, Xiaohong Gong, Seth G.N. Grant, Anne Hoffmann, Claire Homan, Elaine Y. Hsiao, Guillaume Huguet, Lachlan Jolly, Eunjoon Kim, Peter C. Kind, Jaewon Ko, Janine M. Lamonica, Marianna Leonzino, Natalia V. Malkova, Carla Marini, Caterina Michetti, Caterina Montani, Mireille Montcouquiol, Maïté M. Moreau, Edoardo Moretto, Alysson Renato Muotri, Emily K. Osterweil, Maria Passafaro, Olga Peñagarikano, Alan K. Percy, Duyen Pham, Katy Phelan, Laura Ricceri, Yoann Saillour, Carlo Sala, Nathalie Sans, Sara Sarasua, Maria Luisa Scattoni, Michael J. Schmeisser, Charles E. Schwartz, Yiping Shen, Chuan Tan, Daniel C. Tarquinio, Sophie R. Thomson, Chiara Verpelli, Kazuhiro Yamakawa, Zhaolan Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c97f80d4c0b770dbc0b6984c2acf55d
https://doi.org/10.1016/b978-0-12-800109-7.01002-5
https://doi.org/10.1016/b978-0-12-800109-7.01002-5