Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Seth D. Kasowitz"'
Autor:
Rong Liu, Seth D. Kasowitz, David Homolka, N. Adrian Leu, Jordan T. Shaked, Gordon Ruthel, Devanshi Jain, Huijuan Lin, Scott Keeney, Mengcheng Luo, Ramesh S. Pillai, P. Jeremy Wang
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110110- (2021)
Summary: Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood. RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is highly expressed in pachytene cells. Here we identify an essential ro
Externí odkaz:
https://doaj.org/article/5e6e1c32c1214f81825e5a7b07b206dd
Autor:
Seth D Kasowitz, Jun Ma, Stephen J Anderson, N Adrian Leu, Yang Xu, Brian D Gregory, Richard M Schultz, P Jeremy Wang
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007412 (2018)
The N6-methyladenosine (m6A) modification is the most prevalent internal RNA modification in eukaryotes. The majority of m6A sites are found in the last exon and 3' UTRs. Here we show that the nuclear m6A reader YTHDC1 is essential for embryo viabili
Externí odkaz:
https://doaj.org/article/96984f59b2b140f0a301bad88184fee4
Autor:
Baolu Shi, Jiangyang Xue, Jian Zhou, Seth D Kasowitz, Yuanwei Zhang, Guanxiang Liang, Yongjuan Guan, Qinghua Shi, Mingxi Liu, Jiahao Sha, Xiaoyan Huang, P Jeremy Wang
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007175 (2018)
The microrchidia (MORC) family proteins are chromatin-remodelling factors and function in diverse biological processes such as DNA damage response and transposon silencing. Here, we report that mouse Morc2b encodes a functional germ cell-specific mem
Externí odkaz:
https://doaj.org/article/6cf2830a2caa47e9ada36b7ee582e7c1
Autor:
Mingxi Liu, Qinghua Shi, Yongjuan Guan, Xiaoyan Huang, Yuanwei Zhang, P. Jeremy Wang, Seth D. Kasowitz, Guanxiang Liang, Jiangyang Xue, Jiahao Sha, Baolu Shi, Jian Zhou
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007175 (2018)
PLoS Genetics
PLoS Genetics
The microrchidia (MORC) family proteins are chromatin-remodelling factors and function in diverse biological processes such as DNA damage response and transposon silencing. Here, we report that mouse Morc2b encodes a functional germ cell-specific mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fb2f788795ade54a27de97101ee296
http://europepmc.org/articles/PMC5785033?pdf=render
http://europepmc.org/articles/PMC5785033?pdf=render
Autor:
Seth D. Kasowitz, P. Jeremy Wang
Mammals have one pair of sex chromosomes, X and Y. Sex chromosomes are derived from an ordinary pair of ancestral autosomes. In contrast with autosomes, sex chromosomes differ drastically in genomic structure, gene contents, and transcription status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc726b2ef878af184ba82a562d00737a
https://doi.org/10.1016/b978-0-12-801238-3.64436-7
https://doi.org/10.1016/b978-0-12-801238-3.64436-7
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
The germ cell lineage is specified early in embryogenesis and undergoes complex developmental programs to generate gametes. Here, we conducted genetic studies to investigate the role of Utf1 (Undifferentiated embryonic cell transcription factor 1) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7d551d9fe695dbe755a9394a7dbe41
http://europepmc.org/articles/PMC5722945
http://europepmc.org/articles/PMC5722945
Publikováno v:
Epigenetics & Chromatin
Background Genomic imprinting is the epigenetic process by which a subset of genes is expressed from only one allele based on the parent of origin. To date there are approximately 150 confirmed autosomal imprinted loci in the mammalian genome. The ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b4c3c0dda41ae0f60fe00300d3c5bd
https://doi.org/10.1186/1756-8935-6-s1-p68
https://doi.org/10.1186/1756-8935-6-s1-p68
Publikováno v:
Epigenetics & Chromatin
Background Meiotic crossingover is an important checkpoint in almost all sexually reproducing eukaryotic organisms and is mediated by the Synaptonemal Complex (SC) during meiosis I. In this process homologous chromosomes exchange sequence information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5598a091b838fd9c54fa7ed9cdf2bc6e
https://doi.org/10.1186/1756-8935-6-s1-p19
https://doi.org/10.1186/1756-8935-6-s1-p19
Autor:
Rachel J. O’Neill, Michael B. Murphy, Benjamin R. Carone, Seth D. Kasowitz, Michael J. O'Neill
Publikováno v:
Biology of Reproduction. 78:193-193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa55ab2394bd1467e873e2bb537997d8
https://doi.org/10.1093/biolreprod/78.s1.193
https://doi.org/10.1093/biolreprod/78.s1.193
Autor:
Rong Liu, Seth D. Kasowitz, David Homolka, N. Adrian Leu, Jordan T. Shaked, Gordon Ruthel, Devanshi Jain, Huijuan Lin, Scott Keeney, Mengcheng Luo, Ramesh S. Pillai, P. Jeremy Wang
Publikováno v:
BASE-Bielefeld Academic Search Engine
Cell Reports, Vol 37, Iss 11, Pp 110110-(2021)
Cell reports
Cell Reports, Vol 37, Iss 11, Pp 110110-(2021)
Cell reports
SUMMARY Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood. RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is highly expressed in pachytene cells. Here we identify an essential rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ca2347ed539738d73f5dfe778f37b4