Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Seth D. DePuy"'
Autor:
Michael A. Kelberman, Jacki M. Rorabaugh, Claire R. Anderson, Alexia Marriott, Seth D. DePuy, Kurt Rasmussen, Katharine E. McCann, Jay M. Weiss, David Weinshenker
Publikováno v:
Neurobiology of Aging. 125:98-108
Accumulation of hyperphosphorylated tau in the locus coeruleus (LC) is a ubiquitous feature of prodromal Alzheimer’s disease (AD), and LC neurons degenerate as AD progresses. Tau-mediated LC dysfunction may contribute to early neuropsychiatric symp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424dfa04835fd809a208b1fc9f5d73a1
https://doi.org/10.1016/j.neurobiolaging.2023.01.016
https://doi.org/10.1016/j.neurobiolaging.2023.01.016
Autor:
David Weinshenker, Allan I. Levey, Seth D. DePuy, James J. Lah, Jacki M. Rorabaugh, Termpanit Chalermpalanupap, Kurt Rasmussen, Robert M. Cohen
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8dfa2b47bea679ccfab1ea7d3cf6f1
https://doi.org/10.1016/j.jalz.2018.06.2891
https://doi.org/10.1016/j.jalz.2018.06.2891
Autor:
Stephen B. G. Abbott, Seth D. DePuy, Ruth L. Stornetta, Melissa B. Coates, Thanh Nguyen, Patrice G. Guyenet
Publikováno v:
The Journal of Neuroscience. 33:3164-3177
Activation of rostral ventrolateral medullary catecholaminergic (RVLM-CA) neurons e.g., by hypoxia is thought to increase sympathetic outflow thereby raising blood pressure (BP). Here we test whether these neurons also regulate breathing and cardiova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c07641e535dc86f1dd787d99f43a35b
https://doi.org/10.1523/jneurosci.1046-12.2013
https://doi.org/10.1523/jneurosci.1046-12.2013
Autor:
Seth D. DePuy, Ilana B. Witten, Karl Deisseroth, Melissa B. Coates, Ruth L. Stornetta, Genrieta Bochorishvili, Patrice G. Guyenet
Publikováno v:
The Journal of Neuroscience. 33:1486-1497
The C1 neurons are a nodal point for blood pressure control and other autonomic responses. Here we test whether these rostral ventrolateral medullary catecholaminergic (RVLM-CA) neurons use glutamate as a transmitter in the dorsal motor nucleus of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5616a37206f0eae3ec9a581345eaa59d
https://doi.org/10.1523/jneurosci.4269-12.2013
https://doi.org/10.1523/jneurosci.4269-12.2013
Publikováno v:
The Journal of Physiology. 589:903-917
The ventrolateral pons contains the A5 group of noradrenergic neurons which regulate the circulation and probably breathing. The present experiments were designed to identify these neurons definitively in vivo, to examine their response to chemorecep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f9ae87308242c4b78a30a7af6f4fba
https://doi.org/10.1113/jphysiol.2010.198374
https://doi.org/10.1113/jphysiol.2010.198374
Publikováno v:
The Journal of Neuroscience. 31:1981-1990
We used optogenetics to determine the global respiratory effects produced by selectively stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test whether these neurons detect changes in the partial pressure of CO2, and he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1c56ca3bc8d9404b22b9e431592d24
https://doi.org/10.1523/jneurosci.4639-10.2011
https://doi.org/10.1523/jneurosci.4639-10.2011
Autor:
Patrice G. Guyenet, Ruth L. Stornetta, Roy Kanbar, Stephen B. G. Abbott, Seth D. DePuy, Michal G. Fortuna
Publikováno v:
Journal of Applied Physiology. 108:995-1002
In this review, we examine why blood pressure (BP) and sympathetic nerve activity (SNA) increase during a rise in central nervous system (CNS) Pco2 (central chemoreceptor stimulation). CNS acidification modifies SNA by two classes of mechanisms. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e397476a957dc1a45ee1d34a5f786b0d
https://doi.org/10.1152/japplphysiol.00712.2009
https://doi.org/10.1152/japplphysiol.00712.2009
Autor:
Patrice G. Guyenet, Douglas A. Bayliss, Seth D. DePuy, Stephen B. G. Abbott, Michal G. Fortuna, Ruth L. Stornetta
Publikováno v:
Respiratory Physiology & Neurobiology. 168:59-68
Breathing automaticity and CO(2) regulation are inseparable neural processes. The retrotrapezoid nucleus (RTN), a group of glutamatergic neurons that express the transcription factor Phox2b, may be a crucial nodal point through which breathing automa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b1c9a001b40397af90df2c8f5bede8
https://doi.org/10.1016/j.resp.2009.02.001
https://doi.org/10.1016/j.resp.2009.02.001
Autor:
Thurl E. Harris, Stephen B. G. Abbott, Gavin H. West, Ruth L. Stornetta, Patrice G. Guyenet, Michal G. Fortuna, Seth D. DePuy
Publikováno v:
The Journal of Neuroscience. 29:5806-5819
The retrotrapezoid “nucleus” (RTN), located in the rostral ventrolateral medullary reticular formation, contains a bilateral cluster of ∼1000 glutamatergic noncatecholaminergic Phox2b-expressing propriobulbar neurons that are activated by CO2in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5c27c431eb09f76b3beb17843b5bcb
https://doi.org/10.1523/jneurosci.1106-09.2009
https://doi.org/10.1523/jneurosci.1106-09.2009
Autor:
Paula Q. Barrett, Philippe Lory, James C. Garrison, Junlan Yao, Isabelle Bidaud, Changlong Hu, Fraydoon Rastinejad, Carlos Gonzalez, Seth D. DePuy, William E. McIntire
Publikováno v:
Proceedings of the National Academy of Sciences. 103:14590-14595
Gβγ, a ubiquitous second messenger, relays external signals from G protein-coupled receptors to networks of intracellular effectors, including voltage-dependent calcium channels. Unlike high-voltage-activated Ca 2+ channels, the inhibition of low-v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41ab21d197cbf702d71d3b19d047936
https://doi.org/10.1073/pnas.0603945103
https://doi.org/10.1073/pnas.0603945103