Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Seth A. Climans"'
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 4311-4328 (2023)
Primary central nervous system (CNS) tumours are heterogeneous, with different treatment pathways and prognoses depending on their histological and molecular classification. Due to their anatomical location, all CNS tumours, regardless of malignancy,
Externí odkaz:
https://doaj.org/article/0d7dd66aa2f045fb8528fb67eafc7367
Autor:
Michelle Paff, Nardin Samuel, Noor Alsafwani, Darcia Paul, Phedias Diamandis, Seth A. Climans, Walter Kucharczyk, Mandy Yi Rong Ding, Andrew F. Gao, Andres M. Lozano
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Leukoencephalopathy with brain calcifications and cysts (LCC; also known as Labrune syndrome) is a rare genetic microangiopathy caused by biallelic mutations in SNORD118. The mechanisms by which loss-of-function mutations in SNORD
Externí odkaz:
https://doaj.org/article/5ca03fa18bd84c048808dd4b3d6b62b0
Autor:
Yajur Iyengar, Julien Hébert, Seth A. Climans, Alexandra Muccilli, Sydney Lee, Abhilasha P. Boruah, Kiran T. Thakur, Jonathon Solnik, Richard A. Wennberg, Gregory S. Day, David F. Tang-Wai
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundFor patients with anti-N-methyl-D-aspartate receptor encephalitis (NMDARE) and ovarian teratoma, “conservative” surgical approaches (complete or partial unilateral oophorectomy or bilateral partial oophorectomies) are associated with cl
Externí odkaz:
https://doaj.org/article/3c655cf21be94af5bb6eb0b594a5e524
Autor:
Angela Sekely, Lori J Bernstein, Kristin L Campbell, Warren P Mason, Normand Laperriere, Navya Kalidindi, Rosemarylin Or, Ronald Ramos, Seth A Climans, Gregory R Pond, Barbara Ann Millar, David Shultz, Derek S Tsang, Gelareh Zadeh, Kim Edelstein
Publikováno v:
Neuro-Oncology Practice. 10:89-96
Background In addition to poor survival rates, individuals with glioblastoma (GBM) are at risk of neurocognitive impairment due to multiple factors. This study aimed to characterize neurocognitive impairment, neurobehavioral symptoms, fatigue, sleep
Publikováno v:
Journal of Neuro-Oncology. 159:665-674
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. :1-6
Background: Cerebral radionecrosis, a subacute or late effect of radiotherapy, can be debilitating and difficult to treat. Steroids can reduce symptoms, but have significant long-term side effects. Bevacizumab has been shown to reduce edema and other
Publikováno v:
Neuro Oncol
Background Malignant gliomas are treated with temozolomide chemoradiotherapy. Because pneumocystis pneumonia (PCP) can occur in patients receiving temozolomide, the product monograph recommends PCP prophylaxis during temozolomide chemoradiotherapy. N
Publikováno v:
Epilepsy and Behavior Case Reports, Vol 7, Iss C, Pp 58-60 (2017)
Externí odkaz:
https://doaj.org/article/187c08432b914aaab3f41ac7b54e04de
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. :1-7
Background: Medical assistance in dying (MAiD), also known as physician-assisted death, is currently legal in several locations across the globe. Brain cancer or its treatments can lead to cognitive impairment, which can impact decision-making capaci
Molecular testing for adolescent and young adult central nervous system tumors: A Canadian guideline
Autor:
Mary Jane Lim-Fat, Maria Macdonald, Sarah Lapointe, Seth Andrew Climans, Chantel Cacciotti, Manik Chahal, Sebastien Perreault, Derek S. Tsang, Andrew Gao, Stephen Yip, Julia Keith, Julie Bennett, Vijay Ramaswamy, Jay Detsky, Uri Tabori, Sunit Das, Cynthia Hawkins
Publikováno v:
Frontiers in Oncology. 12
The 2021 World Health Organization (WHO) classification of CNS tumors incorporates molecular signatures with histology and has highlighted differences across pediatric vs adult-type CNS tumors. However, adolescent and young adults (AYA; aged 15–39)