Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Session 835 (Poster)"'
Publikováno v:
Innovation in Aging
Aging Cell
Aging Cell
Skeletal muscle aging is a major cause of disability and frailty in the elderly. The progressive impairment of skeletal muscle with aging was recently linked to a disequilibrium between damage and repair. Macrophages participate in muscle tissue repa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947afc39fc17e2c1c289d63dfc87531c
https://doi.org/10.1111/acel.13032
https://doi.org/10.1111/acel.13032
Autor:
Kara L. Lubieniecki, Zachary S. Clayton, Melanie L. Zigler, Matthew J. Rossman, Douglas R. Seals, Jamie N. Justice, Rachel A. Gioscia-Ryan
Publikováno v:
Innovation in Aging
Aging is associated with progressive declines in physical function. However, it is unknown if consumption of a western-style diet (WD; high-fat and sucrose, low fiber), compared with a non-WD (healthy diet), accelerates declines in physical function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa065ccf56b2041ef89e31bbc7cdd4b5
https://doi.org/10.1093/geroni/igz038.391
https://doi.org/10.1093/geroni/igz038.391
Publikováno v:
Innovation in Aging
Immuno-hematologic function (IHF) is increasingly being recognized as a central component of health status in older age. In this study, we sought to identify homogeneous IHF profiles regarding their relationship to all-cause mortality. We then studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b64f45700316aef72ec7c053b00f38
http://europepmc.org/articles/PMC6846537
http://europepmc.org/articles/PMC6846537
Autor:
Meghan E. McGee-Lawrence, Carlos M. Isales, Ahmed M. Elmansi, Robert T. Bragg, Tanner Mobley, Dmitry Kondrikov, William D. Hill, Mark W. Hamrick
Publikováno v:
Innovation in Aging
The age-related increase of the tryptophan metabolite, kynurenine (KYN), has been associated with osteoporosis progression. Increased activity of by Indoleamine-(2,3)-dioxygenase(IDO), are responsible for the elevation of KYN levels in bone tissue. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16915b5d0859597ed6be995d6b789ba3
http://europepmc.org/articles/PMC6844752
http://europepmc.org/articles/PMC6844752
Publikováno v:
Innovation in Aging
While caloric restriction (CR) provides highly robust improvements to longevity and health, dietary restriction of the essential amino acid methionine can provide similar benefits including improved metabolic function and increased longevity. Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31f567f34be86b8c91109d823633ad2
http://europepmc.org/articles/PMC6846655
http://europepmc.org/articles/PMC6846655
Publikováno v:
Innovation in Aging
Mosaicism, the presence of two or more genotypically or karyotypically distinct populations of cells in a single individual, plays an important role in human disease. Mosaicism can result in mutations and/or chromosomal alterations such as loss, gain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f2170b07ff5f80d2a29ed2a99be99d
https://doi.org/10.1093/geroni/igz038.394
https://doi.org/10.1093/geroni/igz038.394
Autor:
Beverly Orsak, Nicolas Musi, Hanyu Liang, Claudia V. Colmenares, Nattapol Sathavarodom, Vinutha Ganapathy
Publikováno v:
Innovation in Aging
Older and obese subjects have increased levels of free fatty acids (FFA) in plasma that may mediate the inflammation and insulin resistance seen in these individuals. Data generated mostly in cells and rodents suggest that toll like receptor 4 (TLR4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48e7612fb948219bcfa3c4c2ec934c8
https://doi.org/10.1093/geroni/igz038.393
https://doi.org/10.1093/geroni/igz038.393
Publikováno v:
Innovation in Aging
Previous cross-sectional studies have shown young adult baboons (~5-6 y.o.), subjected to intrauterine growth restriction (IUGR) by maternal calorie restriction during pregnancy and lactation, exhibit ventricular remodeling with mildly impaired heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fe6cf931b2bd0c351f5f06410faff5
http://europepmc.org/articles/PMC6846081
http://europepmc.org/articles/PMC6846081
Autor:
Peter S. Rabinovitch, Rudolph Stuppard, Ana P. Valencia, Gustavo Valencia, David J. Marcinek, Jeremy Whitson
Publikováno v:
Innovation in Aging
Over 80% of American adults exceed their daily recommended intake of sugar (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3f1f977cb3d1f0acc27cce7fee590d
https://doi.org/10.1093/geroni/igz038.402
https://doi.org/10.1093/geroni/igz038.402
Publikováno v:
Innovation in Aging
Ageing conveys the greatest risk for cardiovascular disease (CVD) development, which is the dominant cause of mortality in developed nations. High density lipoprotein (HDL) particles mediate reverse cholesterol transport, are anti-inflammatory and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0798ac1dec61f97dbcc1ed7f175d6692
http://europepmc.org/articles/PMC6845530
http://europepmc.org/articles/PMC6845530