Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sesquile Ramon"'
Autor:
Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime
Publikováno v:
PPAR Research, Vol 2012 (2012)
Peroxisome proliferator activated receptor (PPAR)-γ is a nuclear hormone receptor that is activated by multiple agonists including thiazolidinediones, prostaglandins, and synthetic oleanolic acids. Many PPARγ ligands are under investigation as pote
Externí odkaz:
https://doaj.org/article/c4494efac2bf49b2b174d05bad06f797
Autor:
Charles N. Serhan, Syed Nuruddin, Jørn Eivind Tungen, Dag Erlend Olberg, Sesquile Ramon, Marius Aursnes, Romain A. Colas, Trond Vidar Hansen, Frode Willoch
Publikováno v:
Organicbiomolecular chemistry. 16(36)
Protectin D1 is a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models. Herein the preparation of the first synthetic analog of protectin D1, named 22-F-PD1, is presented t
Autor:
Richard P. Phipps, Luis Martinez-Sobrido, Charles N. Serhan, Sesquile Ramon, Nina Kim, Julie Sahler, David J. Topham, Eric A. Feldsott, Steven F. Baker
Publikováno v:
The Journal of Immunology. 193:6031-6040
Influenza viruses remain a critical global health concern. More efficacious vaccines are needed to protect against influenza virus, yet few adjuvants are approved for routine use. Specialized proresolving mediators (SPMs) are powerful endogenous bioa
Autor:
Marius Aursnes, Jesmond Dalli, Sesquile Ramon, Romain A. Colas, Trond Vidar Hansen, Charles N. Serhan, Anders Vik, Jørn Eivind Tungen
Publikováno v:
Journal of Natural Products
Protectin D1 (PD1 (3)), a C22-dihydroxylated polyunsaturated fatty acid biosynthesized from all-Z-docosahexaenoic acid, belongs to the new family of endogenous mediators referred to as specialized pro-resolving lipid mediators. PD1 (3) is a natural p
Publikováno v:
European Journal of Immunology. 44:357-369
Specialized proresolving mediators are endogenous bioactive lipid molecules that play a fundamental role in the regulation of inflammation and its resolution. Lipoxins and other specialized proresolving mediators have been identified in important imm
Autor:
Thomas I. Murant, Richard P. Phipps, Safiehkhatoon Moshkani, Andrea Bottaro, Simona Bancos, Sesquile Ramon, Julie Sahler, Patricia J. Sime, Thomas H. Thatcher
Publikováno v:
The Journal of Immunology. 189:4740-4747
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily. PPARγ, a ligand-activated transcription factor, has important anti-inflammatory and antiproliferative functions, and it has been associated
Publikováno v:
The Journal of Immunology. 189:1036-1042
The resolution of inflammation is an active and dynamic process critical in maintaining homeostasis. Newly identified lipid mediators have been recognized as key players during the resolution phase. These specialized proresolving mediators (SPM) cons
Autor:
Patricia J. Simpson-Haidaris, Steven E. Feldon, Richard P. Phipps, Naxin Guo, Sesquile Ramon, Collynn F. Woeller, Stephen J. Pollock
Publikováno v:
PPAR Research
PPAR Research, Vol 2010 (2010)
PPAR Research, Vol 2010 (2010)
The use of targeted cancer therapies in combination with conventional chemotherapeutic agents and/or radiation treatment has increased overall survival of cancer patients. However, longer survival is accompanied by increased incidence of comorbiditie
Autor:
Sesquile Ramon, Charles N. Serhan, Jørn Eivind Tungen, Julia M. Sanger, Jesmond Dalli, Marius Aursnes, Jeremy W. Winkler, Trond Vidar Hansen
Publikováno v:
The American journal of pathology. 186(4)
Inflammation and its natural resolution are host-protective responses triggered by infection or injury. The resolution phase of inflammation is regulated by enzymatically produced specialized pro-resolving mediators. We recently identified a new clas
Autor:
Pratiti Bandopadhayay, Sui Huang, Mark W. Kieran, Charles N. Serhan, Sesquile Ramon, Romain A. Colas, Chantal Barksdale, Megan L. Sulciner, Dipak Panigrahy
Publikováno v:
The FASEB Journal. 29
Background: Tumor recurrence occurs in one-third of patients with medulloblastoma. Current clinical approaches to reduce medulloblastoma tumor burden, including chemotherapy, may contribute to rela...