Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Seshagiri, Duvvuri"'
Publikováno v:
Journal of Electromagnetic Waves and Applications. 37:428-440
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2844ab2bdf6c31cb095325baf0a3c0ef
https://doi.org/10.1080/09205071.2022.2145505
https://doi.org/10.1080/09205071.2022.2145505
Akademický článek
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Autor:
Gautam Borthakur, Seshagiri Duvvuri, Vivian Ruvolo, Durga Nand Tripathi, Sujan Piya, Jared Burks, Rodrigo Jacamo, Kensuke Kojima, Peter Ruvolo, Juan Fueyo-Margareto, Marina Konopleva, Michael Andreeff
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139254 (2015)
MDM2 (mouse double minute 2) inhibitors that activate p53 and induce apoptosis in a non-genotoxic manner are in clinical development for treatment of leukemias. P53 can modulate other programmed cell death pathways including autophagy both transcript
Externí odkaz:
https://doaj.org/article/1e29b2e8f776433bb52a37ec5080a36e
Publikováno v:
Signal, Image & Video Processing; Feb2023, Vol. 17 Issue 1, p157-164, 8p
Autor:
Suk Young Yoo, Nianxiang Zhang, Seshagiri Duvvuri, Peter P. Ruvolo, Steven M. Kornblau, Michael Andreeff, Zhihong Zeng, Kevin R. Coombes, Marina Konopleva, Jared K. Burks, Numsen Hail, Yihua Qiu, Rodrigo Jacamo, George A. Calin, Rongqing Pan, Liran Zhou, Vivian Ruvolo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843:1969-1977
We recently discovered that the protein phosphatase 2A (PP2A) B55α subunit (PPP2R2A) is under-expressed in primary blast cells and is unfavorable for remission duration in AML patients. In this study, reverse phase protein analysis (RPPA) of 230 pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831c9fba7d3538b63d3ec2353687bb74
https://doi.org/10.1016/j.bbamcr.2014.05.006
https://doi.org/10.1016/j.bbamcr.2014.05.006
Autor:
Steven M. Kornblau, R. Eric Davis, Min Zhang, Zhiqiang Wang, Seshagiri Duvvuri, Kevin R. Coombes, Michael Kauffman, Michael Andreeff, Vivian Ruvolo, Yihua Qiu, Sharon Shacham, Hagop M. Kantarjian, Kensuke Kojima, Jared K. Burks, Archana Dilip, Nianxiang Zhang
Publikováno v:
Blood. 121:4166-4174
Chromosomal region maintenance 1 (CRM1) is a nuclear export receptor recognizing proteins bearing a leucine-rich nuclear export signal. CRM1 is involved in nuclear export of tumor suppressors such as p53. We investigated the prognostic significance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69fe14a02896efcc77920ebb09f86ff
https://doi.org/10.1182/blood-2012-08-447581
https://doi.org/10.1182/blood-2012-08-447581
Autor:
Vivian Ruvolo, Felipe Samaniego, Kensuke Kojima, Seshagiri Duvvuri, Michael Andreeff, Anas Younes
Publikováno v:
Cancer. 118:1023-1031
BACKGROUND: Despite the high complete response rates achieved with fludarabine-based regimens, relapse is inevitable in chronic lymphocytic leukemia (CLL). Relapsed patients often acquire deletions of the short arm of chromosome 17 (del[17p]), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce05e768e99d00bf73d814527d1ed3fe
https://doi.org/10.1002/cncr.26360
https://doi.org/10.1002/cncr.26360
Autor:
Julie C. Watt, Seshagiri Duvvuri, Hagop M. Kantarjian, Ismael Samudio, Duncan Mak, Vivian Ruvolo, Gautam Borthakur, Dajun Yang, Karen Clise-Dwyer
Publikováno v:
Leukemia & Lymphoma. 51:911-919
Non-mutational inactivation of p53 is frequent in acute myeloid leukemia (AML) via overexpression of MDM2. We report that treatment with MI-63, a novel inhibitor of MDM2, activates p53 signaling to induce apoptosis in AML cell lines and primary sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3257700e76b8c3319b3390c5e3db6a
https://doi.org/10.3109/10428191003731325
https://doi.org/10.3109/10428191003731325
Autor:
Borys Korchin, Ismael Samudio, Michael Andreeff, Hagop M. Kantarjian, Heinrich Taegtmeyer, Kumar Kaluarachchi, Michael Fiegl, Marina Konopleva, William G. Bornmann, Romain Harmancey, Seshagiri Duvvuri
Publikováno v:
Journal of Clinical Investigation. 120:142-156
The traditional view is that cancer cells predominately produce ATP by glycolysis, rather than by oxidation of energy-providing substrates. Mitochondrial uncoupling — the continuing reduction of oxygen without ATP synthesis — has recently been sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705e4ef51b3fb739adc02fdbee51e17c
https://doi.org/10.1172/jci38942
https://doi.org/10.1172/jci38942
Autor:
Seshagiri Duvvuri, Marina Konopleva, Peter P. Ruvolo, Juan Fueyo-Margareto, Kensuke Kojima, Gautam Borthakur, Rodrigo Jacamo, Vivian Ruvolo, Sujan Piya, Durga Nand Tripathi, Jared K. Burks, Michael Andreeff
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0139254 (2015)
PLoS ONE, Vol 10, Iss 10, p e0139254 (2015)
MDM2 (mouse double minute 2) inhibitors that activate p53 and induce apoptosis in a non-genotoxic manner are in clinical development for treatment of leukemias. P53 can modulate other programmed cell death pathways including autophagy both transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4fcadded43733efc03d91762fe84de7
http://europepmc.org/articles/PMC4595506
http://europepmc.org/articles/PMC4595506