Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Seshadri S Vasan"'
Autor:
César Muñoz-Fontela, Lina Widerspick, Randy A Albrecht, Martin Beer, Miles W Carroll, Emmie de Wit, Michael S Diamond, William E Dowling, Simon G P Funnell, Adolfo García-Sastre, Nora M Gerhards, Rineke de Jong, Vincent J Munster, Johan Neyts, Stanley Perlman, Douglas S Reed, Juergen A Richt, Ximena Riveros-Balta, Chad J Roy, Francisco J Salguero, Michael Schotsaert, Lauren M Schwartz, Robert A Seder, Joaquim Segalés, Seshadri S Vasan, Ana María Henao-Restrepo, Dan H Barouch
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010161 (2022)
The global response to Coronavirus Disease 2019 (COVID-19) is now facing new challenges such as vaccine inequity and the emergence of SARS-CoV-2 variants of concern (VOCs). Preclinical models of disease, in particular animal models, are essential to
Externí odkaz:
https://doaj.org/article/2e0188b1403e45f2bd75009acab0b6c7
Autor:
Ryan J Farr, Christina L Rootes, Louise C Rowntree, Thi H O Nguyen, Luca Hensen, Lukasz Kedzierski, Allen C Cheng, Katherine Kedzierska, Gough G Au, Glenn A Marsh, Seshadri S Vasan, Chwan Hong Foo, Christopher Cowled, Cameron R Stewart
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009759 (2021)
The host response to SARS-CoV-2 infection provide insights into both viral pathogenesis and patient management. The host-encoded microRNA (miRNA) response to SARS-CoV-2 infection, however, remains poorly defined. Here we profiled circulating miRNAs f
Externí odkaz:
https://doaj.org/article/9d54b16d350a4c6ca04d6e50ac0757f6
Autor:
Renaud Lacroix, Andrew R McKemey, Norzahira Raduan, Lim Kwee Wee, Wong Hong Ming, Teoh Guat Ney, Siti Rahidah A A, Sawaluddin Salman, Selvi Subramaniam, Oreenaiza Nordin, Norhaida Hanum A T, Chandru Angamuthu, Suria Marlina Mansor, Rosemary S Lees, Neil Naish, Sarah Scaife, Pam Gray, Geneviève Labbé, Camilla Beech, Derric Nimmo, Luke Alphey, Seshadri S Vasan, Lee Han Lim, Nazni Wasi A, Shahnaz Murad
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42771 (2012)
BackgroundDengue is the most important mosquito-borne viral disease. In the absence of specific drugs or vaccines, control focuses on suppressing the principal mosquito vector, Aedes aegypti, yet current methods have not proven adequate to control th
Externí odkaz:
https://doaj.org/article/15d1f1254ff84a4eb81b3ceaad8e50d0
Autor:
Gough G. Au, Glenn A. Marsh, Alexander J. McAuley, Suzanne Lowther, Lee Trinidad, Sarah Edwards, Shawn Todd, Jennifer Barr, Matthew P. Bruce, Timothy B. Poole, Sheree Brown, Rachel Layton, Sarah Riddell, Brenton Rowe, Elisha Soldani, Willy W. Suen, Jemma Bergfeld, John Bingham, Jean Payne, Peter A. Durr, Trevor W. Drew, Seshadri S. Vasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the infectious disease COVID-19, which has rapidly become an international pandemic with significant impact on healthcare systems and the global economy. To assi
Externí odkaz:
https://doaj.org/article/8df430e8b15f452184c4e6bc6bcb1338
Autor:
Nagendrakumar B. Singanallur, Petrus Jansen van Vuren, Alexander J. McAuley, Matthew P. Bruce, Michael J. Kuiper, Stella M. Gwini, Shane Riddell, Sarah Goldie, Trevor W. Drew, Kim R. Blasdell, Mary Tachedjian, Shruthi Mangalaganesh, Simran Chahal, Leon Caly, Julian D. Druce, Jennifer A. Juno, Stephen J. Kent, Adam K. Wheatley, Seshadri S. Vasan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Plasma samples taken at different time points from donors who received either AstraZeneca (Vaxzevria) or Pfizer (Comirnaty) or Moderna (Spikevax) coronavirus disease-19 (COVID-19) vaccine were assessed in virus neutralization assays against Delta and
Externí odkaz:
https://doaj.org/article/804d089de38c45d8bfb667c42f472492
Tracking Co-Occurrence of N501Y, P681R, and Other Key Mutations in SARS-CoV-2 Spike for Surveillance
Autor:
Carol Lee, Shruthi Mangalaganesh, Laurence O. W. Wilson, Michael J. Kuiper, Trevor W. Drew, Seshadri S. Vasan
Publikováno v:
Zoonotic Diseases; Volume 2; Issue 3; Pages: 147-162
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has produced five variants of concern (VOC) to date. The important spike mutation ‘N501Y’ is common to Alpha, Beta, Gamma, and Omicron VOC, while the ‘P681R’ is key to Delta’s
Autor:
Avinash V. Karpe, Thao V. Nguyen, Rohan M. Shah, Gough G. Au, Alexander J. McAuley, Glenn A. Marsh, Sarah Riddell, Seshadri S. Vasan, David J. Beale
Publikováno v:
Metabolites; Volume 12; Issue 11; Pages: 1151
The global threat of COVID-19 has led to an increased use of metabolomics to study SARS-CoV-2 infections in animals and humans. In spite of these efforts, however, understanding the metabolome of SARS-CoV-2 during an infection remains difficult and i
Autor:
Hardik A. Jain, Vinti Agarwal, Chaarvi Bansal, Anupama Kumar, Faheem Faheem, Muzaffar-Ur-Rehman Mohammed, Sankaranarayanan Murugesan, Moana M. Simpson, Avinash V. Karpe, Rohitash Chandra, Christopher A. MacRaild, Ian K. Styles, Amanda L. Peterson, Matthew A. Cooper, Carl M. J. Kirkpatrick, Rohan M. Shah, Enzo A. Palombo, Natalie L. Trevaskis, Darren J. Creek, Seshadri S. Vasan
Although various vaccines are now commercially available, they have not been able to stop the spread of COVID-19 infection completely. An excellent strategy to quickly get safe, effective, and affordable COVID-19 treatment is to repurpose drugs that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0987d3061527ac29e7c57c04f1ca5937
https://doi.org/10.20944/preprints202209.0323.v1
https://doi.org/10.20944/preprints202209.0323.v1
Autor:
Alexander J. McAuley, Petrus Jansen van Vuren, Muzaffar-Ur-Rehman Mohammed, null Faheem, Sarah Goldie, Shane Riddell, Nathan J. Gödde, Ian K. Styles, Matthew P. Bruce, Simran Chahal, Stephanie Keating, Kim R. Blasdell, Mary Tachedjian, Carmel M. O’Brien, Nagendrakumar Balasubramanian Singanallur, John Noel Viana, Aditya V. Vashi, Carl M. Kirkpatrick, Christopher A. MacRaild, Rohan M. Shah, Elizabeth Vincan, Eugene Athan, Darren J. Creek, Natalie L. Trevaskis, Sankaranarayanan Murugesan, Anupama Kumar, Seshadri S. Vasan
Publikováno v:
Viruses; Volume 14; Issue 11; Pages: 2417
The repurposing of licenced drugs for use against COVID-19 is one of the most rapid ways to develop new and alternative therapeutic options to manage the ongoing pandemic. Given the approximately 8,000 licenced compounds available from Compounds Aust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479ca1661b4ed933c7965c7e9dfc85ee
https://doi.org/10.20944/preprints202209.0288.v1
https://doi.org/10.20944/preprints202209.0288.v1
Autor:
Christopher A. MacRaild, Muzaffar-Ur-Rehman Mohammed, null Faheem, Sankaranarayanan Murugesan, Ian K. Styles, Amanda L. Peterson, Carl M. J. Kirkpatrick, Matthew A. Cooper, Enzo A. Palombo, Moana M. Simpson, Hardik A. Jain, Vinti Agarwal, Alexander J. McAuley, Anupama Kumar, Darren J. Creek, Natalie L. Trevaskis, Seshadri S. Vasan
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11851
SARS-CoV-2, is the cause of the COVID-19 pandemic which has claimed more than six million lives worldwide, devastating the economy and overwhelming healthcare systems globally. The development of new drug molecules and vaccines has played a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7963c6de562984c0e7e0bd38b1abf34
https://doi.org/10.20944/preprints202209.0310.v1
https://doi.org/10.20944/preprints202209.0310.v1