Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Servio H, Ramirez"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Growing body of evidence suggests that cardiovascular risk factor, asymmetric dimethylarginine (ADMA), can be implicated in the pathogenesis of neurodegenerative and psychiatric disorders. In part, ADMA can affect brain health negatively modulating c
Externí odkaz:
https://doaj.org/article/6488eb7dd62f442ba1eb330f2268327d
Autor:
Brian M. Leonard, Vladimir V. Shuvaev, Trent A. Bullock, Kalpani N. Udeni Galpayage Dona, Vladimir R. Muzykantov, Allison M. Andrews, Servio H. Ramirez
Publikováno v:
Bioengineering, Vol 11, Iss 3, p 200 (2024)
The neuroinflammatory cascade triggered by traumatic brain injury (TBI) represents a clinically important point for therapeutic intervention. Neuroinflammation generates oxidative stress in the form of high-energy reactive oxygen and nitrogen species
Externí odkaz:
https://doaj.org/article/fc46f6c9b1954fa8b6e78fbee33f10a7
Publikováno v:
Bioengineering, Vol 10, Iss 7, p 817 (2023)
More than a billion people are affected by neurological disorders, and few have effective therapeutic options. A key challenge that has prevented promising preclinically proven strategies is the translation gap to the clinic. Humanized tissue enginee
Externí odkaz:
https://doaj.org/article/5f1a97fffe654650ac5635e54a35a194
Autor:
Tetyana P. Buzhdygan, Cassidy R. Rodrigues, Hannah M. McGary, Jana A. Khan, Allison M. Andrews, Scott M. Rawls, Servio H. Ramirez
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Synthetic cathinones are a category of psychostimulants belonging to the growing number of designer drugs also known as “Novel Psychoactive Substances” (NPS). In recent years, NPS have gained popularity in the recreational dru
Externí odkaz:
https://doaj.org/article/f7c2476807914651b5f565838335f0b6
Autor:
Killian S. Hanlon, Jonah C. Meltzer, Tetyana Buzhdygan, Ming J. Cheng, Miguel Sena-Esteves, Rachel E. Bennett, Timothy P. Sullivan, Roshanak Razmpour, Yi Gong, Carrie Ng, Josette Nammour, Daniela Maiz, Simon Dujardin, Servio H. Ramirez, Eloise Hudry, Casey A. Maguire
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 320-332 (2019)
Adeno-associated virus (AAV) capsid libraries have generated improved transgene delivery vectors. We designed an AAV library construct, iTransduce, that combines a peptide library on the AAV9 capsid with a Cre cassette to enable sensitive detection o
Externí odkaz:
https://doaj.org/article/52e01ca87cb94b9eaa2bbaf0a5e3ec5e
Autor:
Tetyana P. Buzhdygan, Brandon J. DeOre, Abigail Baldwin-Leclair, Trent A. Bullock, Hannah M. McGary, Jana A. Khan, Roshanak Razmpour, Jonathan F. Hale, Peter A. Galie, Raghava Potula, Allison M. Andrews, Servio H. Ramirez
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105131- (2020)
As researchers across the globe have focused their attention on understanding SARS-CoV-2, the picture that is emerging is that of a virus that has serious effects on the vasculature in multiple organ systems including the cerebral vasculature. Observ
Externí odkaz:
https://doaj.org/article/8b09ad12a1a144d6870c6f939be164bc
Autor:
Victoria Lutgen, Srinivas D Narasipura, Hannah J Barbian, Maureen Richards, Jennillee Wallace, Roshanak Razmpour, Tetyana Buzhdygan, Servio H Ramirez, Lisa Prevedel, Eliseo A Eugenin, Lena Al-Harthi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008381 (2020)
HIV invades the brain during acute infection. Yet, it is unknown whether long-lived infected brain cells release productive virus that can egress from the brain to re-seed peripheral organs. This understanding has significant implication for the brai
Externí odkaz:
https://doaj.org/article/bca497f3a30241ec928887702485b2b4
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-21 (2018)
Abstract Extracellular vesicles (EVs) are heterogeneous, nano-sized vesicles that are shed into the blood and other body fluids, which disperse a variety of bioactive molecules (e.g., protein, mRNA, miRNA, DNA and lipids) to cellular targets over lon
Externí odkaz:
https://doaj.org/article/07d68cc2a9e74d5e8dc8b51d3a48af13
Publikováno v:
Bioengineering; Volume 10; Issue 7; Pages: 817
More than a billion people are affected by neurological disorders, and few have effective therapeutic options. A key challenge that has prevented promising preclinically proven strategies is the translation gap to the clinic. Humanized tissue enginee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::73deb56e7e99b95b208be10c32e7c0ba
Autor:
Divya Sagar, Narendra P. Singh, Rashida Ginwala, Xiaofang Huang, Ramila Philip, Mitzi Nagarkatti, Prakash Nagarkatti, Konstantin Neumann, Jürgen Ruland, Allison M. Andrews, Servio H. Ramirez, Zafar K. Khan, Pooja Jain
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The mechanism of dendritic cells (DCs) recruitment across the blood brain barrier (BBB) during neuroinflammation has been the least explored amongst all leukocytes. For cells of myeloid origin, while integrins function at the level of adhesi
Externí odkaz:
https://doaj.org/article/f3480ad339694c2197a255d3370edaa6