Zobrazeno 1 - 10
of 1 249
pro vyhledávání: '"Serum metabolites"'
Autor:
Tong Tong, Congcong Zhu, John J. Farrell, Zainab Khurshid, Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Neuroimaging Initiative, Eden R. Martin, Margaret A. Pericak-Vance, Li-San Wang, William S. Bush, Gerard D. Schellenberg, Jonathan L. Haines, Wei Qiao Qiu, Kathryn L. Lunetta, Lindsay A. Farrer, Xiaoling Zhang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Blood-derived mitochondrial DNA copy number (mtDNA-CN) is a proxy measurement of mitochondrial function in the peripheral and central systems. Abnormal mtDNA-CN not only indicates impaired mtDNA replication and transcription machi
Externí odkaz:
https://doaj.org/article/6359a6836b184b369a74d2bbfb50ce84
Publikováno v:
Poultry Science Journal, Vol 12, Iss 2, Pp 203-210 (2024)
A total of 200 day-old COBB-500 chicks were randomly allocated into four dietary treatments with five replications and ten birds per replicate for 28 days to select the most effective forms of plantain herb for broiler performance and meat quality. T
Externí odkaz:
https://doaj.org/article/b949b116915b4a5fbd88353a604ce9da
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The increase in environmental temperature led to economic losses in the poultry industry, urging the use of feed supplements to mitigate the negative effects on chick's welfare and performance. Therefore, this study aimed to examine the effe
Externí odkaz:
https://doaj.org/article/fb3677e69f184d3f917486dbaab864d0
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/03f1884854834495b0c8a7dbd2186977
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundIntervertebral disk degeneration (IVDD) is a complex degenerative skeletal condition, potentially influenced by micronutrients and serum metabolites in its etiology. However, the exact causal relationship between these factors and IVDD rema
Externí odkaz:
https://doaj.org/article/12a509f6c32a4db691ddafc71109b4a3
Autor:
Yi-Ming Ren, Wei-Yu Hou, Bao-You Fan, Yuan-Hui Duan, Yun-Bo Sun, Tao Yang, Han-Ji Zhang, Tian-Wei Sun, Meng-Qiang Tian
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
BackgroundThere is an urgent need to confirm biomarkers reflecting the pathogenesis and targeted drugs of lower back pain or/and sciatica in clinical practice. This study aimed to conduct a two sample bidirectional Mendelian randomization (MR) analys
Externí odkaz:
https://doaj.org/article/5849e37a93b24c8da78f487a2db5b5fa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundWe employed Mendelian randomization (MR) to investigate the causal relationship between the gut microbiota and lymphoid leukemia, further exploring the causal relationships among immune cells, lymphoid leukemia, and potential metabolic medi
Externí odkaz:
https://doaj.org/article/e1ef3c515417468f9392271405d7db1c
The causal relationship between serum metabolites and acne vulgaris: a Mendelian randomization study
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In individuals with acne vulgaris, alterations occur in serum metabolite composition, yet the exact causal link between these metabolites and acne development remains elusive. Using genome-wide association datasets, we performed bidirectiona
Externí odkaz:
https://doaj.org/article/0dfa4eccda4747cb9e41b69eec32a0cf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Previous research has linked serum metabolite levels to iridocyclitis, yet their causal relationship remains unexplored. This study investigated this potential causality by analyzing pooled data from 7824 iridocyclitis patients in a Genome-W
Externí odkaz:
https://doaj.org/article/a24422391b1e44679999579b7daeaa88
Autor:
Lili He, Qingjuan Zuo, Sai Ma, Guorui Zhang, Zhongli Wang, Tingting Zhang, Jianlong Zhai, Yifang Guo
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Purpose To investigate the effects of canagliflozin (20 mg/kg) on Dahl salt-sensitive (DSS) rat gut microbiota and salt-sensitive hypertension-induced kidney injury and further explore its possible mechanism.Methods Rats were fed a high-salt diet to
Externí odkaz:
https://doaj.org/article/58889af7424a453b90e6376a55939d37