Role of STAT3 (signal transducer and activator of transcription 3) activation and its regulation by PTPRT (protein receptor tyrosine phosphatase type T) and response to paclitaxel and cetuximab in patients (P) with recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC)

Autor: Cirauqui, BC, Peguera, AB, Pi-Sunyer, AQ, Serrano, JLR, Vinolas, MD, Garcia, IT, Garcia, VQ, Vila, MM, Chaib, I, Riera, LC, Diez, AF, Salarich, AP, Company, LA, Fernandez, SE, Peinado, GB, Rubio, CL, Guisasola, CP, Cardus, AM, Costa, RR, Nin, RM

Publikováno v: Annals of Oncology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7f1b0fabff95069307b045e016b88a84
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3378

MET-Dependent Activation of STAT3 as Mediator of Resistance to MEK Inhibitors in KRAS-Mutant Lung Cancer

Autor: Lazzari, C, Karachaliou, N, Verlicchi, A, Servat, CC, Capitan, AG, Servat, JC, Bertran-Alamillo, J, Vila, MAM, Chaib, I, Serrano, JLR, Cao, P, De Marinis, F, Gregorc, V, Rosell, R

Publikováno v: Journal of Thoracic Oncology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::8ea8557823454e0247f3205d2ed8b064
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6072

STAT3 and Src-YAP1 Inhibition Results in Greater Necitumumab Sensitivity in Lung Squamous Cell Carcinoma

Autor: Verlicche, A, Karachaliou, N, Lazzari, C, Servat, CC, Capitan, AG, Servat, JC, Bertran-Alamillo, J, Vila, MAM, Chaib, I, Serrano, JLR, Dazzi, C, Cao, P, Rose, R

Publikováno v: Journal of Thoracic Oncology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::b36a347154d74505607af15bfa8b87ba
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6092

Deciphering the impact of STAT3 activation mediated by PTPRT promoter hypermethylation as biomarker of response to paclitaxel-plus-cetuximab in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

Autor: Cirauqui BC; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain., Peguera AB; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Pi-Sunyer AQ; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain.; Department of Pathology, Germans Trias i Pujol Hospital, Badalona, Spain., Ferrando-Díez A; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain., Serrano JLR; Molecular Biology Unit, Hematology Laboratory, Catalan Institute of Oncology (ICO), Badalona, Spain., Viñolas MD; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., García IT; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., García VQ; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Oukadour IC; Laboratory of Cellular and Molecular Biology, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Valencia AG; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Vergara PH; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain., de Aguirre Egaña I; Molecular Biology Unit, Hematology Laboratory, Catalan Institute of Oncology (ICO), Badalona, Spain., Herrero CQ; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Resistance Cancer Predictive Biomarkers Group, ProCURE Program-Catalan Institute of Oncology, Badalona, Spain., Carbonell OM; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Paradís AL; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Esteve A; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Vila MM; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Rosell R; Laboratory of Cellular and Molecular Biology, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Martínez-Cardús A; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Mesía R; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.

Publikováno v: Head & neck [Head Neck] 2025 Jan; Vol. 47 (1), pp. 57-67. Date of Electronic Publication: 2024 Jul 27.