Waning and boosting of antibody Fc-effector functions upon SARS-CoV-2 vaccination.

Autor: Tong X; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA., McNamara RP; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA., Avendaño MJ; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., Serrano EF; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., García-Salum T; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, 30322, USA., Pardo-Roa C; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., Bertera HL; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA., Chicz TM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA., Levican J; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., Poblete E; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., Salinas E; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., Muñoz A; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile., Riquelme A; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile.; Department of Gastroenterology, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, 8331150, Chile., Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA. galter@mgh.harvard.edu., Medina RA; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile. rafael.medina@emory.edu.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile. rafael.medina@emory.edu.; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, 30322, USA. rafael.medina@emory.edu.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. rafael.medina@emory.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Jul 13; Vol. 14 (1), pp. 4174. Date of Electronic Publication: 2023 Jul 13.

Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines.

Autor: Bartsch YC; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02138, USA., Tong X; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02138, USA., Kang J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02138, USA., Avendaño MJ; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile., Serrano EF; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile., García-Salum T; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR)-COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile., Pardo-Roa C; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR)-COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile., Riquelme A; Advanced Interdisciplinary Rehabilitation Register (AIRR)-COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.; Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.; Department of Health Sciences, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile., Cai Y; Division of Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Renzi I; Moderna Inc., Cambridge, MA 02138, USA., Stewart-Jones G; Moderna Inc., Cambridge, MA 02138, USA., Chen B; Division of Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Medina RA; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR)-COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02138, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2022 Apr 27; Vol. 14 (642), pp. eabn9243. Date of Electronic Publication: 2022 Apr 27.

Preserved Omicron Spike specific antibody binding and Fc-recognition across COVID-19 vaccine platforms.

Autor: Bartsch Y; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA., Tong X; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA., Kang J; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA., José Avendaño M; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Serrano EF; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., García-Salum T; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Pardo-Roa C; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Riquelme A; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Medina RA; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Alter G; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA.; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Health Sciences, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Dec 27. Date of Electronic Publication: 2021 Dec 27.

Long-lasting neutralizing antibody responses in SARS-CoV-2 seropositive individuals are robustly boosted by immunization with the CoronaVac and BNT162b2 vaccines.

Autor: Muena NA; Laboratorio de Virología Molecular, Fundación Ciencia & Vida, Av. Zañartu 1482, Santiago, Chile., García-Salum T; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Pardo-Roa C; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Serrano EF; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; PhD Program in Biological Sciences, Mention in Molecular Genetics and Microbiology, Faculty of Biological Science, Pontificia Universidad Católica de Chile, Santiago, Chile., Levican J; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Avendaño MJ; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; PhD Program in Biological Sciences, Mention in Molecular Genetics and Microbiology, Faculty of Biological Science, Pontificia Universidad Católica de Chile, Santiago, Chile., Almonacid LI; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Valenzuela G; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Poblete E; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Strohmeier S; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Salinas E; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Haslwanter D; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Dieterle ME; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., González C; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Otorhinolaryngology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Riquelme A; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Health Sciences, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Krammer F; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tischler ND; Laboratorio de Virología Molecular, Fundación Ciencia & Vida, Av. Zañartu 1482, Santiago, Chile.; Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile., Medina RA; Department of Pediatric Infectious Diseases and Immunology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Advanced Interdisciplinary Rehabilitation Register (AIRR) - COVID-19 Working Group, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 May 18. Date of Electronic Publication: 2021 May 18.