A structural biology community assessment of AlphaFold2 applications

Autor: Akdel, Mehmet, Pires, Douglas EV, Pardo, Eduard Porta, Jänes, Jürgen, Zalevsky, Arthur O, Mészáros, Bálint, Bryant, Patrick, Good, Lydia L, Laskowski, Roman A, Pozzati, Gabriele, Shenoy, Aditi, Zhu, Wensi, Kundrotas, Petras, Serra, Victoria Ruiz, Rodrigues, Carlos HM, Dunham, Alistair S, Burke, David, Borkakoti, Neera, Velankar, Sameer, Frost, Adam, Basquin, Jérôme, Lindorff-Larsen, Kresten, Bateman, Alex, Kajava, Andrey V, Valencia, Alfonso, Ovchinnikov, Sergey, Durairaj, Janani, Ascher, David B, Thornton, Janet M, Davey, Norman E, Stein, Amelie, Elofsson, Arne, Croll, Tristan I, Beltrao, Pedro

Publikováno v: Nature Structural & Molecular Biology, 29 (11)
Akdel, M, Pires, D E, Porta Pardo, E, Jänes, J, Zalevsky, A O, Meszaros, B, Bryant, P, Good, L L, Laskowski, R A, Pozzati, G, Shenoy, A, Zhu, W, Kundrotas, P, Serra, V R, Rodrigues, C H M, Dunham, A S, Burke, D, Borkakoti, N, Velankar, S, Frost, A, Basquin, J, Lindorff-Larsen, K, Bateman, A, Kajava, A, Valencia, A, Ovchinnikov, S, Durairaj, J, Ascher, D B, Thornton, J M, Davey, N E, Stein, A, Elofsson, A, Croll, T & Beltrao, P 2022, ' A structural biology community assessment of AlphaFold2 applications ', Nature Structural & Molecular Biology, vol. 29, no. 11 . https://doi.org/10.1038/s41594-022-00849-w
Nature Structural and Molecular Biology 29 (2022) 11
Nature Structural and Molecular Biology, 29(11), 1056-1067

Most proteins fold into 3D structures that determine how they function and orchestrate the biological processes of the cell. Recent developments in computational methods for protein structure predictions have reached the accuracy of experimentally de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5120d87bb9bff7ff683ea7fd4c584

A structural biology community assessment of AlphaFold2 applications.

Autor: Akdel M; Bioinformatics Group, Department of Plant Sciences, Wageningen University and Research, Wageningen, the Netherlands., Pires DEV; School of Computing and Information Systems, University of Melbourne, Melbourne, Victoria, Australia., Pardo EP; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain.; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Jänes J; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Zalevsky AO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation., Mészáros B; European Molecular Biology Laboratory, Heidelberg, Germany., Bryant P; Dep of Biochemistry and Biophysics and Science for Life Laboratory, Solna, Sweden., Good LL; Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Laskowski RA; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Pozzati G; Dep of Biochemistry and Biophysics and Science for Life Laboratory, Solna, Sweden., Shenoy A; Dep of Biochemistry and Biophysics and Science for Life Laboratory, Solna, Sweden., Zhu W; Dep of Biochemistry and Biophysics and Science for Life Laboratory, Solna, Sweden., Kundrotas P; Dep of Biochemistry and Biophysics and Science for Life Laboratory, Solna, Sweden., Serra VR; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Rodrigues CHM; School of Computing and Information Systems, University of Melbourne, Melbourne, Victoria, Australia., Dunham AS; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Burke D; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Borkakoti N; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Velankar S; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Frost A; Department of Biochemistry and Biophysics University of California, San Francisco, CA, USA., Basquin J; Department of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried, Germany., Lindorff-Larsen K; Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Bateman A; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Kajava AV; Université de Montpellier, Centre de Recherche en Biologie Cellulaire de Montpellier (CRBM) CNRS, Montpellier, France., Valencia A; Barcelona Supercomputing Center (BSC), Barcelona, Spain. alfonso.valencia@bsc.es., Ovchinnikov S; Faculty of Arts and Sciences, Division of Science, Harvard University, Cambridge, MA, USA. so@fas.harvard.edu., Durairaj J; Biozentrum, University of Basel, Basel, Switzerland. janani.durairaj@gmail.com., Ascher DB; School of Chemistry and Molecular Biology, University of Queensland, Brisbane, Queensland, Australia. d.ascher@uq.edu.au., Thornton JM; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK. thornton@ebi.ac.uk., Davey NE; Institute of Cancer Research, London, UK. norman.davey@icr.ac.uk., Stein A; Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark. amelie.stein@bio.ku.dk., Elofsson A; Dep of Biochemistry and Biophysics and Science for Life Laboratory, Solna, Sweden. arne@bioinfo.se., Croll TI; Cambridge Institute for Medical Research, Department of Haematology, The University of Cambridge, Cambridge, UK. tic20@cam.ac.uk., Beltrao P; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK. pbeltrao@ethz.ch.; Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland. pbeltrao@ethz.ch.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2022 Nov; Vol. 29 (11), pp. 1056-1067. Date of Electronic Publication: 2022 Nov 07.