Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Serra, EG"'
Autor:
Schwerd, T, Bryant, RV, Pandey, S, Capitani, M, Meran, L, Cazier, J-B, Jung, J, Mondal, K, Parkes, M, Mathew, CG, Fiedler, K, McCarthy, DJ, WGS500 Consortium, Oxford IBD cohort study investigators, COLORS in IBD group investigators, UK IBD Genetics Consortium, Sullivan, PB, Rodrigues, A, Travis, SPL, Moore, C, Sambrook, J, Ouwehand, WH, Roberts, DJ, Danesh, J, INTERVAL Study, Russell, RK, Wilson, DC, Kelsen, JR, Cornall, R, Denson, LA, Kugathasan, S, Knaus, UG, Serra, EG, Anderson, CA, Duerr, RH, McGovern, D Pb, Cho, J, Powrie, F, Li, V Sw, Muise, AM, Uhlig, HH
Genetic defects that affect intestinal epithelial barrier function can present with very early-onset inflammatory bowel disease (VEOIBD). Using whole-genome sequencing, a novel hemizygous defect in NOX1 encoding NAPDH oxidase 1 was identified in a pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6147d1baeb06520d537ea903c7fd8511
Autor:
Luo, Y, de Lange, KM, Jostins, L, Moutsianas, L, Randall, J, Kennedy, NA, Lamb, CA, McCarthy, S, Ahmad, T, Edwards, C, Serra, EG, Hart, A, Hawkey, C, Mansfield, JC, Mowat, C, Newman, WG, Nichols, S, Pollard, M, Satsangi, J, Simmons, A, Tremelling, M, Uhlig, H, Wilson, DC, Lee, JC, Prescott, NJ, Lees, CW, Mathew, CG, Parkes, M, Barrett, JC, Anderson, CA
To further resolve the genetic architecture of the inflammatory bowel diseases ulcerative colitis and Crohn’s disease, we sequenced the whole genomes of 4,280 patients at low coverage and compared them to 3,652 previously sequenced population contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96812a84e483206bb44513c008c312c5
Autor:
Schwerd, T, Bryant, RV, Pandey, S, Capitani, M, Meran, L, Cazier, J-B, Jung, J, Mondal, K, Parkes, M, Mathew, CG, Fiedler, K, McCarthy, DJ, Sullivan, PB, Rodrigues, A, Travis, SPL, Moore, C, Sambrook, J, Ouwehand, WH, Roberts, DJ, Danesh, J, Russell, RK, Wilson, DC, Kelsen, JR, Cornall, R, Denson, LA, Kugathasan, S, Knaus, UG, Serra, EG, Anderson, CA, Duerr, RH, McGovern, DPB, Cho, J, Powrie, F, Li, VSW, Muise, AM, Uhlig, HH
Publikováno v:
Mucosal immunology; March 2018, Vol. 11 Issue: 2 p562-574, 13p
Akademický článek
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Autor:
Serra EG; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Schwerd T; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Dr. von Hauner Children's Hospital, Department of Pediatrics, University Hospital, Ludwig Maximilians University, Munich, Germany., Moutsianas L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Cavounidis A; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Fachal L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Pandey S; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Kammermeier J; Great Ormond Street Hospital, London, UK., Croft NM; Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.; The Royal London Children's Hospital, Barts Health NHS Trust, London, UK., Posovszky C; Universitätsklinikum, Ulm, Germany., Rodrigues A; Department of Paediatrics, University of Oxford, Oxford, UK., Russell RK; Royal Hospital for Children, Glasgow, UK., Barakat F; Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.; The Royal London Children's Hospital, Barts Health NHS Trust, London, UK., Auth MKH; Alder Hey Children's Hospital, Liverpool, UK., Heuschkel R; Addenbrooke's Hospital, Cambridge, UK., Zilbauer M; Addenbrooke's Hospital, Cambridge, UK., Fyderek K; Department of Paediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Krakow, Poland., Braegger C; Division of Gastroenterology and Nutrition and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland., Travis SP; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Satsangi J; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Institute of Genetics and Molecular Medicine, University of Edinburgh, Scotland, UK., Parkes M; IBD Research Unit, Department of Gastroenterology, Addenbrooke's Hospital, Cambridge, UK., Thapar N; Great Ormond Street Hospital, London, UK., Ferry H; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Matte JC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Gilmour KC; Great Ormond Street Hospital, London, UK., Wedrychowicz A; Department of Paediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Krakow, Poland., Sullivan P; Department of Paediatrics, University of Oxford, Oxford, UK., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Sambrook J; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Ouwehand W; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Roberts D; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant - Oxford Centre, Level 2, John Radcliffe Hospital, Oxford, UK.; Biomedical Research Centre, Oxford - Haematology Theme, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Danesh J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Baeumler TA; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Fulga TA; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Carrami EM; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Ahmed A; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.; National Institute of Health Research Oxford Biomedical Research Centre, Surgical Innovation and Evaluation and Molecular Diagnostics Themes, University of Oxford, Oxford, UK., Wilson R; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Barrett JC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Elkadri A; Department of Biochemistry and Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; SickKids Inflammatory Bowel Disease Centre and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada., Griffiths AM; Department of Biochemistry and Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; SickKids Inflammatory Bowel Disease Centre and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada., Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA., Shah N; Great Ormond Street Hospital, London, UK., Muise AM; Department of Biochemistry and Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; SickKids Inflammatory Bowel Disease Centre and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada., Wilson DC; Child Life and Health, University of Edinburgh, Edinburgh, UK., Uhlig HH; Translational Gastroenterology Unit, University of Oxford, Oxford, UK. holm.uhlig@ndm.ox.ac.uk.; Department of Paediatrics, University of Oxford, Oxford, UK. holm.uhlig@ndm.ox.ac.uk., Anderson CA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. carl.anderson@sanger.com.
Publikováno v:
Nature communications [Nat Commun] 2022 Jun 22; Vol. 13 (1), pp. 3576. Date of Electronic Publication: 2022 Jun 22.
Autor:
Serra EG; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Schwerd T; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Dr. von Hauner Children's Hospital, Department of Pediatrics, University Hospital, Ludwig Maximilians University, Munich, Germany., Moutsianas L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Cavounidis A; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Fachal L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Pandey S; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Kammermeier J; Great Ormond Street Hospital, London, UK., Croft NM; Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.; The Royal London Children's Hospital, Barts Health NHS Trust, London, UK., Posovszky C; Universitätsklinikum, Ulm, Germany., Rodrigues A; Department of Paediatrics, University of Oxford, Oxford, UK., Russell RK; Royal Hospital for Children, Glasgow, UK., Barakat F; Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.; The Royal London Children's Hospital, Barts Health NHS Trust, London, UK., Auth MKH; Alder Hey Children's Hospital, Liverpool, UK., Heuschkel R; Addenbrooke's Hospital, Cambridge, UK., Zilbauer M; Addenbrooke's Hospital, Cambridge, UK., Fyderek K; Department of Paediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Krakow, Poland., Braegger C; Division of Gastroenterology and Nutrition and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland., Travis SP; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Satsangi J; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Institute of Genetics and Molecular Medicine, University of Edinburgh, Scotland, UK., Parkes M; IBD Research Unit, Department of Gastroenterology, Addenbrooke's Hospital, Cambridge, UK., Thapar N; Great Ormond Street Hospital, London, UK., Ferry H; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Matte JC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Gilmour KC; Great Ormond Street Hospital, London, UK., Wedrychowicz A; Department of Paediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Krakow, Poland., Sullivan P; Department of Paediatrics, University of Oxford, Oxford, UK., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Sambrook J; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Ouwehand W; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Roberts D; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant - Oxford Centre, Level 2, John Radcliffe Hospital, Oxford, UK.; Biomedical Research Centre, Oxford - Haematology Theme, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Danesh J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Baeumler TA; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Fulga TA; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Carrami EM; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Ahmed A; Weatherall Institute of Molecular Medicine and the Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.; National Institute of Health Research Oxford Biomedical Research Centre, Surgical Innovation and Evaluation and Molecular Diagnostics Themes, University of Oxford, Oxford, UK., Wilson R; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Barrett JC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Elkadri A; Department of Biochemistry and Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; SickKids Inflammatory Bowel Disease Centre and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada., Griffiths AM; Department of Biochemistry and Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; SickKids Inflammatory Bowel Disease Centre and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada., Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA., Shah N; Great Ormond Street Hospital, London, UK., Muise AM; Department of Biochemistry and Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; SickKids Inflammatory Bowel Disease Centre and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada., Wilson DC; Child Life and Health, University of Edinburgh, Edinburgh, UK., Uhlig HH; Translational Gastroenterology Unit, University of Oxford, Oxford, UK. holm.uhlig@ndm.ox.ac.uk.; Department of Paediatrics, University of Oxford, Oxford, UK. holm.uhlig@ndm.ox.ac.uk., Anderson CA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. carl.anderson@sanger.com.
Publikováno v:
Nature communications [Nat Commun] 2020 Feb 21; Vol. 11 (1), pp. 995. Date of Electronic Publication: 2020 Feb 21.
Autor:
Peters C; 1 Department of Endocrinology and Great Ormond Street Hospital for Children, London, United Kingdom., Nicholas AK; 2 Department of Laboratory Medicine, Great Ormond Street Hospital for Children, London, United Kingdom., Schoenmakers E; 2 Department of Laboratory Medicine, Great Ormond Street Hospital for Children, London, United Kingdom., Lyons G; 2 Department of Laboratory Medicine, Great Ormond Street Hospital for Children, London, United Kingdom., Langham S; 1 Department of Endocrinology and Great Ormond Street Hospital for Children, London, United Kingdom., Serra EG; 3 University of Cambridge Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom., Sebire NJ; 4 Department of Human Genetics, The Wellcome Trust Sanger Institute, Hinxton, United Kingdom., Muzza M; 5 Division of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy., Fugazzola L; 5 Division of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy.; 6 Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Schoenmakers N; 2 Department of Laboratory Medicine, Great Ormond Street Hospital for Children, London, United Kingdom.
Publikováno v:
Thyroid : official journal of the American Thyroid Association [Thyroid] 2019 Jun; Vol. 29 (6), pp. 790-801.
Autor:
Cangul H; Department of Medical Genetics, Istanbul Medipol University, International School of Medicine, Istanbul, Turkey., Liao XH; Department of Medicine, The University of Chicago, Chicago, Illinois, USA., Schoenmakers E; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom (UK)., Kero J; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland.; Department of Paediatrics, Turku University Hospital, Turku, Finland., Barone S; University of Cincinnati and Veterans Administration Hospital, Cincinnati, Ohio, USA., Srichomkwun P; Department of Medicine, The University of Chicago, Chicago, Illinois, USA., Iwayama H; Department of Medicine, The University of Chicago, Chicago, Illinois, USA., Serra EG; Department of Human Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Saglam H; Uludag University School of Medicine, Department of Paediatric Endocrinology, Bursa, Turkey., Eren E; Uludag University School of Medicine, Department of Paediatric Endocrinology, Bursa, Turkey., Tarim O; Uludag University School of Medicine, Department of Paediatric Endocrinology, Bursa, Turkey., Nicholas AK; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom (UK)., Zvetkova I; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom (UK)., Anderson CA; Department of Human Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Frankl FEK; Department of Medical Genetics and Division of Renal Medicine, University of Cambridge, Cambridge, UK., Boelaert K; Institute of Metabolism and Systems Research, University of Birmingham and Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Edgbaston, Birmingham, UK., Ojaniemi M; PEDEGO Research Center and MRC Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland., Jääskeläinen J; Department of Pediatrics, University of Eastern Finland and Kuopio University, Hospital, Kuopio, Finland., Patyra K; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland., Löf C; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland., Williams ED; Thyroid Carcinogenesis Group, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Soleimani M; University of Cincinnati and Veterans Administration Hospital, Cincinnati, Ohio, USA., Barrett T; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham and Department of Endocrinology, Birmingham Children's Hospital, Birmingham, UK., Maher ER; Department of Medical Genetics, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Chatterjee VK; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom (UK)., Refetoff S; Department of Medicine, The University of Chicago, Chicago, Illinois, USA.; Department of Pediatrics and the Committee on Genetics, The University of Chicago, Chicago, Illinois, USA., Schoenmakers N; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom (UK).
Publikováno v:
JCI insight [JCI Insight] 2018 Oct 18; Vol. 3 (20). Date of Electronic Publication: 2018 Oct 18.
Autor:
Schwerd T; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Dr von Hauner Children's Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany., Bryant RV; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; University of Adelaide, Adelaide, South Australia, Australia., Pandey S; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Capitani M; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Meran L; The Francis Crick Institute, London, UK., Cazier JB; The Wellcome Trust Centre for Human Genetics, Oxford, UK., Jung J; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Mondal K; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Parkes M; Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK., Mathew CG; Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital London, London, UK., Fiedler K; SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., McCarthy DJ; The Wellcome Trust Centre for Human Genetics, Oxford, UK., Sullivan PB; Department of Paediatrics, University of Oxford, Oxford, UK., Rodrigues A; Department of Paediatrics, University of Oxford, Oxford, UK., Travis SPL; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Sambrook J; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Ouwehand WH; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Danesh J; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Russell RK; Department of Paediatric Gastroenterology, The Royal Hospital for Children, Glasgow, UK., Wilson DC; Royal Hospital for Sick Children, Edinburgh, UK.; Child Life and Health, University of Edinburgh, Edinburgh, UK., Kelsen JR; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Cornall R; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, UK., Denson LA; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Kugathasan S; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Knaus UG; Conway Institute, School of Medicine, University College Dublin, Dublin, Ireland.; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland., Serra EG; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Anderson CA; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Duerr RH; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA., McGovern DP; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Cho J; Icahn School of Medicine, Mount Sinai Hospital, New York, New York, USA., Powrie F; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Li VS; The Francis Crick Institute, London, UK., Muise AM; SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Uhlig HH; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK.
Publikováno v:
Mucosal immunology [Mucosal Immunol] 2018 Mar; Vol. 11 (2), pp. 562-574. Date of Electronic Publication: 2017 Nov 01.
Autor:
Luo Y; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; Division of Genetics and Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., de Lange KM; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Jostins L; Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK.; Christ Church, University of Oxford, St Aldates, UK., Moutsianas L; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Randall J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Kennedy NA; Precision Medicine Exeter, University of Exeter, Exeter, UK.; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK., Lamb CA; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne., McCarthy S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Ahmad T; Precision Medicine Exeter, University of Exeter, Exeter, UK.; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK., Edwards C; Department of Gastroenterology, Torbay Hospital, Torbay, Devon, UK., Serra EG; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Hart A; Department of Medicine, St Mark's Hospital, Harrow, Middlesex, UK., Hawkey C; Nottingham Digestive Diseases Centre, Queens Medical Centre, Nottingham, UK., Mansfield JC; Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK., Mowat C; Department of Medicine, Ninewells Hospital and Medical School, Dundee, UK., Newman WG; Genetic Medicine, Manchester Academic Health Science Centre, Manchester, UK.; The Manchester Centre for Genomic Medicine, University of Manchester, Manchester, UK., Nichols S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Pollard M; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Satsangi J; Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK., Simmons A; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.; Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Tremelling M; Gastroenterology & General Medicine, Norfolk and Norwich University Hospital, Norwich, UK., Uhlig H; Translational Gastroenterology Unit and the Department of Paediatrics, University of Oxford, Oxford, United Kingdom., Wilson DC; Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK.; Child Life and Health, University of Edinburgh, Edinburgh, Scotland, UK., Lee JC; Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, Cambridge, UK., Prescott NJ; Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, Guy's Hospital, London, UK., Lees CW; Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK., Mathew CG; Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, Guy's Hospital, London, UK.; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa., Parkes M; Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, Cambridge, UK., Barrett JC; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Anderson CA; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
Publikováno v:
Nature genetics [Nat Genet] 2017 Feb; Vol. 49 (2), pp. 186-192. Date of Electronic Publication: 2017 Jan 09.