Zobrazeno 1 - 10
of 169
pro vyhledávání: '"SerpinB3"'
Autor:
Patrizia Pontisso, Maurizio Parola
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 1, Pp 22-41 (2024)
Chronic liver diseases (CLDs), which are typically characterized by fibrogenic progression towards liver cirrhosis and related complications eventually leading to organ failure and can also lead to the development of primary liver cancers, represent
Externí odkaz:
https://doaj.org/article/fed7b010c5674293ac0eeb4acd60f6ba
Akademický článek
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Publikováno v:
Cancers, Vol 16, Iss 14, p 2579 (2024)
SerpinB3, a member of the serine-protease inhibitor family, has emerged as a crucial player in various physiological and pathological processes. Initially identified as an oncogenic factor in squamous cell carcinomas, SerpinB3’s intricate involveme
Externí odkaz:
https://doaj.org/article/269eb7f8b25b47a2ac2bbfefaea1d503
Autor:
Zixian Huang, Yongju Chen, Rui Chen, Bin Zhou, Yongqiang Wang, Lei Hong, Yuepeng Wang, Jianguang Wang, Xiaoding Xu, Zhiquan Huang, Weiliang Chen
Publikováno v:
Advanced Science, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Head and neck squamous cell carcinoma (HNSCC) is the most common malignant tumor of the head and neck, and the prognosis of patients is poor due to chemotherapeutic resistance. Interestingly, patients with HNSCC induced by human papillomavir
Externí odkaz:
https://doaj.org/article/9cbfa7343c3243098515939270e0c578
Autor:
Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
Publikováno v:
European Journal of Histochemistry, Vol 66, Iss 4 (2022)
We have investigated the change in SerpinB3 during hepatic ischemia and the potential role of its antiprotease activity in cell protection by the administration of wild-type SerpinB3 (SerpinB3-WT) or active loop-deleted recombinant SerpinB3 protein (
Externí odkaz:
https://doaj.org/article/132dd393be9445019719bfe2e49b6ede
Publikováno v:
Cancers, Vol 15, Iss 14, p 3629 (2023)
Hepatocellular carcinoma (HCC) is a common and aggressive cancer with a high mortality rate. The incidence of HCC is increasing worldwide, and the lack of effective screening programs often results in delayed diagnosis, making it a challenging diseas
Externí odkaz:
https://doaj.org/article/788932b63c4d41f0a609ac7612a96471
Autor:
Erica Novo, Andrea Cappon, Gianmarco Villano, Santina Quarta, Stefania Cannito, Claudia Bocca, Cristian Turato, Maria Guido, Marina Maggiora, Francesca Protopapa, Salvatore Sutti, Alessia Provera, Mariagrazia Ruvoletto, Alessandra Biasiolo, Beatrice Foglia, Emanuele Albano, Patrizia Pontisso, Maurizio Parola
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease worldwide. In 20-30% of patients, NAFLD can progress into non-alcoholic steatohepatitis (NASH), eventually leading to fibrosis, cirrhosis and hepatocellular c
Externí odkaz:
https://doaj.org/article/0b2f8a9cdce347ea8e3573b42a3dc766
Autor:
Alessandra Biasiolo, Michele Sandre, Stefania Ferro, Santina Quarta, Mariagrazia Ruvoletto, Gianmarco Villano, Cristian Turato, Maria Guido, Oriano Marin, Patrizia Pontisso
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 739 (2023)
SerpinB3 is a serine protease inhibitor that plays a relevant role in disease progression and cancer by increasing fibrosis, cell proliferation, and invasion, besides conferring resistance to apoptosis. The mechanisms underlying these biological acti
Externí odkaz:
https://doaj.org/article/520129d75eae49a8b20590b0373d1ce4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Jiang Wu, Qiong Guo, Guoliang Zhang, Liying Zhao, Yvguang Lv, Jiaqi Wang, Jiguang Liu, Wei Shi
Publikováno v:
Cancer Medicine, Vol 9, Iss 6, Pp 2213-2222 (2020)
Abstract Oral squamous cell carcinoma (OSCC) has a poor prognosis and a high risk of recurrence. To improve the efficacy of OSCC therapy, it is of great significance to explore gene therapy for OSCC. The use of specific genes to regulate the targeted
Externí odkaz:
https://doaj.org/article/3786fd6751fc441084bbbee394a8933c