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pro vyhledávání: '"Serotonin receptor agonist"'
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Publikováno v:
Drug, Healthcare and Patient Safety
The treatment of migraine is often complicated by insufficient headache relief, a miscellany of side effects and the risk of developing Medication Overuse Headache (MOH). Novel acute therapies have been recently developed and are now in the early pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42eaa0a911c6119a07deef7815c44354
https://doi.org/10.2147/dhps.s304373
https://doi.org/10.2147/dhps.s304373
Autor:
Yu. P. Gerasimenko, O. V. Gorsky, E. Yu. Bazhenova, Tatiana Moshonkina, N. V. Pavlova, I. N. Bogacheva
Publikováno v:
Neuroscience and Behavioral Physiology. 50:599-606
The recovery of motor functions in chronic spinal rats with locomotor training on a treadmill combined with electrical stimulation of the spinal cord was studied. Training to a bipedal gait on a moving band with the body weight supported and use of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c7ba9583efe2a13a16ff21c050df21
https://doi.org/10.1007/s11055-020-00941-y
https://doi.org/10.1007/s11055-020-00941-y
Autor:
Kaifeng Lu, Matthew Butler, Abhijeet Jakate, Danielle McGeeney, Ramesh Boinpally, Antonia Periclou
Publikováno v:
Headache
Objective To evaluate the potential for pharmacokinetic interaction and the safety and tolerability when ubrogepant and sumatriptan are coadministered in a Phase 1 study in healthy participants, and to inform the safety and tolerability of ubrogepant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d67a130c07c20ec0c296948c697fbd
http://europepmc.org/articles/PMC7496299
http://europepmc.org/articles/PMC7496299
Publikováno v:
Journal of Neurosurgery. :1-9
OBJECTIVESumatriptan, a serotonin receptor agonist, has been used in the management of primary headache disorders and has been shown to affect trigeminal dural afferents. There is limited literature on the safety and efficacy of sumatriptan for postc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c22e429944755bc2c5f9c98cb15471d
https://doi.org/10.3171/2019.10.jns192503
https://doi.org/10.3171/2019.10.jns192503
Publikováno v:
Acta gastro-enterologica Belgica. 84(3)
Background : Intestinal pseudo obstruction both acute and chronic is an uncommon severe motility disorder that affect both children and adults, can lead to significant morbidity burden and have no standard management strategy. Prucalopride a highly s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c705a212297c2e0485cb485b1fbbc5c6
https://pubmed.ncbi.nlm.nih.gov/34599567
https://pubmed.ncbi.nlm.nih.gov/34599567
Publikováno v:
Neurourology and Urodynamics. 38:1700-1706
AIMS To evaluate the effect of ASP2205, a selective serotonin 5-HT2c receptor agonist, and Duloxetine on the urethral pressure in healthy female subjects. METHODS Healthy females aged 18 to 55 years were recruited for this phase 1, single site, place
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1739c595cc46c75245966b8c26ec10a
https://doi.org/10.1002/nau.24045
https://doi.org/10.1002/nau.24045
Autor:
Jignyasa Raval, Ankita Yagnik
Objective: The aim of the study was to prepare and evaluate buccal-adhesive tablets of Buspirone HCl that avoid gastric degradation and first pass metabolism, thereby increasing the drug bioavailability and onset of action. Buspirone HCl belongs to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2a638808897a6af85fbaf92e63ada2
https://doi.org/10.9734/bpi/hmms/v4/2632f
https://doi.org/10.9734/bpi/hmms/v4/2632f
Autor:
George Karamanolis, Trygve Hausken, A. Sheptulin, A Papathanasopoulos, Jan Tack, Daniel Keszthelyi, M. Corsetti, T. Milosavljevic, Frank Zerbib, M. Storr, Dan L. Dumitrascu, A. Stengel, Hans Törnblom, Tim Vanuytsel, Giovanni Sarnelli, C. Malagelada, H. De Schepper, Lucas Wauters, Daniel Pohl, Agata Mulak, Ram Dickman, Goran Hauser, D. Rumyantseva, Giovanni Barbara, Jordi Serra, N. Zarate, C. O'Morain, Benoit Coffin, Guillaume Gourcerol, Anne Farmer, Serhat Bor, Vasile Drug, M. Velosa, Annemieke Smet, Edoardo Savarino, Jolien Schol, Paul Enck, M. Waluga, Anna Accarino, O. Storonova
Publikováno v:
United European Gastroenterology Journal
Volume 9
Issue 3
United European Gastroenterology Journal, 9(3), 287-306. SAGE Publications Inc.
Volume 9
Issue 3
United European Gastroenterology Journal, 9(3), 287-306. SAGE Publications Inc.
BACKGROUND: Gastroparesis is a condition characterized by epigastric symptoms and delayed gastric emptying (GE) rate in the absence of any mechanical obstruction. The condition is challenging in clinical practice by the lack of guidance concerning di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01faf1a29acaef013f672c09fd88620a
https://lirias.kuleuven.be/handle/123456789/676027
https://lirias.kuleuven.be/handle/123456789/676027
Publikováno v:
Journal of cardiovascular pharmacology and therapeutics. 26(1)
Introduction: Tegaserod, an orally active, potent 5-hydroxytryptamine-4 serotonin receptor agonist, was previously indicated for irritable bowel syndrome but was voluntarily withdrawn due to potential cardiovascular side effects. In vitro studies sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1b31615ea3fc4aec3bd208a4a8e853
https://pubmed.ncbi.nlm.nih.gov/32672062
https://pubmed.ncbi.nlm.nih.gov/32672062