RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.

Autor: Tetik-Elsherbiny N; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Elsherbiny A; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Setya A; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Gahn J; Cardiovascular Pharmacology, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Tang Y; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Gupta P; Cardiovascular Pharmacology, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Dou Y; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Serke H; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany., Wieland T; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Experimental Pharmacology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Dubrac A; Centre de Recherche, CHU St. Justine, Montreal, Quebec, Canada., Heineke J; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Potente M; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Angiogenesis & Metabolism Laboratory, Center of Vascular Biomedicine, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany., Cordero J; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. julio.cordero@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany. julio.cordero@medma.uni-heidelberg.de., Ola R; Cardiovascular Pharmacology, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. roxana.ola@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany. roxana.ola@medma.uni-heidelberg.de., Dobreva G; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. gergana.dobreva@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany. gergana.dobreva@medma.uni-heidelberg.de.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany. gergana.dobreva@medma.uni-heidelberg.de.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2024 Oct; Vol. 3 (10), pp. 1199-1216. Date of Electronic Publication: 2024 Sep 25.

Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function.

Autor: Wang Y; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany., Elsherbiny A; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Kessler L; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Cordero J; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany., Shi H; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany., Serke H; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany., Lityagina O; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Trogisch FA; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Mohammadi MM; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Institute of Physiology I, Life & Brain Center, Medical Faculty University of Bonn, Bonn, Germany., El-Battrawy I; First Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM), Heidelberg University, Mannheim, Germany.; Bergmannsheil Bochum, Medical Clinic II, Department of Cardiology and Angiology, Ruhr University, 44789, Bochum, Germany., Backs J; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Institute of Experimental Cardiology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany., Wieland T; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Experimental Pharmacology, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Heineke J; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany.; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Dobreva G; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Mannheim, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.

Publikováno v: Nature communications [Nat Commun] 2022 Nov 04; Vol. 13 (1), pp. 6663. Date of Electronic Publication: 2022 Nov 04.

Update on Biomarkers of Chronic Inflammatory Processes Underlying Diabetic Neuropathy.

Autor: Stoian, Adina¹ (AUTHOR) adina.stoian@umfst.ro, Muntean, Carmen² (AUTHOR) carmen.duicu@umfst.ro, Babă, Dragoș-Florin^3,4 (AUTHOR) dragos-florin.baba@umfst.ro, Manea, Andrei⁵ (AUTHOR) andrei17v1997@gmail.com, Dénes, Lóránd⁶ (AUTHOR) lorand.denes@umfst.ro, Simon-Szabó, Zsuzsánna¹ (AUTHOR) florina.gliga@umfst.ro, Kosovski, Irina Bianca¹ (AUTHOR), Nemes-Nagy, Enikő⁷ (AUTHOR) eniko.nemes-nagy@umfst.ro, Gliga, Florina Ioana¹ (AUTHOR), Stoian, Mircea⁸ (AUTHOR) mircea.stoian@umfst.ro

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10395. 25p.

COMP-Ang-1 Improves Glucose Uptake in db/db Mice with Type 2 Diabetes.

Autor: Baum P; Department of Neurology, University of Leipzig, Leipzig, Germany., Paeschke S; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Klöting N; Department of Medicine, University of Leipzig, Leipzig, Germany.; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig, Leipzig, Germany., Blüher M; Department of Medicine, University of Leipzig, Leipzig, Germany., Kern M; Department of Medicine, University of Leipzig, Leipzig, Germany., Serke H; CBTM, Anatomy and Developmental Biology, University of Heidelberg, Mannheim, Germany., Nowicki M; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Kosacka J; Department of Neurology, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany.

Publikováno v: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme [Horm Metab Res] 2020 Sep; Vol. 52 (9), pp. 685-688. Date of Electronic Publication: 2020 Apr 06.

Targeting TANK-binding kinase 1 attenuates painful diabetic neuropathy via inhibiting microglia pyroptosis.

Autor: Liao, Qinming¹ (AUTHOR), Yang, Yimei^1,2 (AUTHOR), Li, Yilu¹ (AUTHOR), Zhang, Jun³ (AUTHOR), Fan, Keke⁴ (AUTHOR), Guo, Yihao⁵ (AUTHOR), Chen, Jun¹ (AUTHOR), Chen, Yinhao¹ (AUTHOR), Zhu, Pian^5,6 (AUTHOR), Huang, Lijin^1,2 (AUTHOR) hlj193@139.com, Liu, Zhongjie^4,5 (AUTHOR) 13580562690@163.com

Publikováno v: Cell Communication & Signaling. 7/19/2024, Vol. 22 Issue 1, p1-17. 17p.