Výsledky vyhledávání - "Serkan Sayin"

Akademický článek

Functional Assay for Measuring Bacterial Degradation of Gemcitabine Chemotherapy

Autor: Serkan Sayin, Amir Mitchell

Publikováno v: Bio-Protocol, Vol 13, Iss 17 (2023)

Drug biotransformation by the host microbiome can impact the therapeutic success of treatment. In the context of cancer, drug degradation can take place within the microenvironment of the targeted tumor by intratumor bacteria. In pancreatic cancer, i

Externí odkaz: https://doaj.org/article/f1430012c18846efb70eefd32a0157c1

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Akademický článek

Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells

Autor: Serkan Sayin, Brittany Rosener, Carmen G Li, Bao Ho, Olga Ponomarova, Doyle V Ward, Albertha JM Walhout, Amir Mitchell

Publikováno v: eLife, Vol 12 (2023)

Drug metabolism by the microbiome can influence anticancer treatment success. We previously suggested that chemotherapies with antimicrobial activity can select for adaptations in bacterial drug metabolism that can inadvertently influence the host’

Externí odkaz: https://doaj.org/article/8dbdb6a6921446178a0f0f6a43a5315f

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Akademický článek

Calix[4]arene Embedded Polyamide Supported Liquid Membrane for Separation of Heavy Metals from Aqueous Solutions

Autor: Seydahmet Cay, Serkan Sayin, Mehmet Soner Engin

Publikováno v: Turkish Journal of Agriculture: Food Science and Technology, Vol 8, Iss 2, Pp 387-391 (2020)

In this study, we aimed to prepare new calixaren embedded mercapto groups supported liquid membranes and to use them in the transport of heavy metals. For this purpose 5,11,17,23-tetra-tert-butyl-25,27-bis(3-thiol-1-oxypropane)-26,28-dihydroxylcalix[

Externí odkaz: https://doaj.org/article/86fbd330a362448e9518598e016c6672

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Akademický článek

Fabrication and Application of a New Modified Electrochemical Sensor Using Newly Synthesized Calixarene-Grafted Mwcnts for Simultaneous Determination of Cu(II) and Pb(II)

Autor: Semahat Kucukkolbasi, Serkan Sayin, Mustafa Yılmaz

Publikováno v: Acta Chimica Slovenica, Vol 66, Iss 4, Pp 839-849 (2019)

A rapid, simple, selective and highly sensitive simultaneous determination of Cu(II) and Pb(II) via newly fashioned 5,11,17,23-tetra-tert-butyl-25,27-dihydrazinamidecarbonylmethoxy-26,28-dihydroxycalix[4]arene-grafted multi-walled carbon nanotubes-mo

Externí odkaz: https://doaj.org/article/c859b74c2453445fac12c418d0906acf

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Akademický článek

Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host

Autor: Brittany Rosener, Serkan Sayin, Peter O Oluoch, Aurian P García González, Hirotada Mori, Albertha JM Walhout, Amir Mitchell

Publikováno v: eLife, Vol 9 (2020)

Metabolism of host-targeted drugs by the microbiome can substantially impact host treatment success. However, since many host-targeted drugs inadvertently hamper microbiome growth, repeated drug administration can lead to microbiome evolutionary adap

Externí odkaz: https://doaj.org/article/7f1eba23afaf4b36ad54274bc601c6ea

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Akademický článek

Harnessing robotic automation and web-based technologies to modernize scientific outreach.

Autor: Orna Dahan, Bat-Shahar Dorfman, Serkan Sayin, Brittany Rosener, Tiffany Hua, Anat Yarden, Amir Mitchell

Publikováno v: PLoS Biology, Vol 17, Iss 6, p e3000348 (2019)

Technological breakthroughs in the past two decades have ushered in a new era of biomedical research, turning it into an information-rich and technology-driven science. This scientific revolution, though evident to the research community, remains opa

Externí odkaz: https://doaj.org/article/f7a8b9c46dd14f9c9fc68a6275d27847

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Akademický článek

Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila.

Autor: Yeliz Yuva-Aydemir, Xia-Lian Xu, Ozkan Aydemir, Eduardo Gascon, Serkan Sayin, Wenke Zhou, Yang Hong, Fen-Biao Gao

Publikováno v: PLoS Genetics, Vol 11, Iss 5, p e1005264 (2015)

Intragenic microRNAs (miRNAs), located mostly in the introns of protein-coding genes, are often co-expressed with their host mRNAs. However, their functional interaction in development is largely unknown. Here we show that in Drosophila, miR-92a and

Externí odkaz: https://doaj.org/article/e9ec18847de64f82b8e79d61b1a28402

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Akademický článek

Gold Electrodes Modified with Calix[4]arene for Electrochemical Determination of Dopamine in the Presence of Selected Neurotransmitters

Autor: Katarzyna Kurzątkowska, Serkan Sayin, Mustafa Yilmaz, Hanna Radecka, Jerzy Radecki

Publikováno v: Sensors, Vol 17, Iss 6, p 1368 (2017)

Here, we present an electrochemical sensor based on gold electrodes modified with calix[4]arene functionalized with carboxypiperidino groups at the upper rim. It has been demonstrated that these groups are involved in a complex formation with dopamin

Externí odkaz: https://doaj.org/article/48d1f52c9bd745db822c31ccce2725d1

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Preparation of Two Calix[4]arene-Functionalized Biopolymers and Evaluations of Their Extraction Abilities Against Cr(VI)/As(V) Anions

Autor: Serkan SAYIN

Publikováno v: Türk Doğa ve Fen Dergisi. 11:70-75

Two calixarene-functionalized biopolymers (calixarene-functionalized chitosan and calixarene-functionalized cellulose) have been synthesized and duly characterized using FTIR, TGA and elemental analysis techniques. Furthermore, their anion extraction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6415baa14704d9f12986973845114e5
https://doi.org/10.46810/tdfd.1036402

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