Výsledky vyhledávání - "Serine Endopeptidases/chemistry/ genetics"

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy

Autor: Lieven Verhoye, Philip Meuleman, Robert Geffers, Thomas Pietschmann, Ali Farhoudi, C. Patrick McClure, Koen Vercauteren, Thomas F. Baumert, Daniel Todt, Sabin Bhuju, Richard J. C. Brown, Eike Steinmann, Tanvi Khera

Publikováno v: Antiviral Research
Antiviral Research, Elsevier Masson, 2017, 139, pp.129-137. ⟨10.1016/j.antiviral.2017.01.001⟩

PMC5292934; Due to the highly restricted species-tropism of Hepatitis C virus (HCV) a limited number of animal models exist for pre-clinical evaluation of vaccines and antiviral compounds. The human-liver chimeric mouse model allows heterologous chal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1048d544256c60f80f1e87e33ba4b7
http://eprints.nottingham.ac.uk/40718/

Zobrazit plný text záznamu

Mutations in the TMPRSS3 gene are a rare cause of childhood nonsyndromic deafness in Caucasian patients

Autor: Andreas Pampanos, Annamaria Pasquadibisceglie, Colette Rossier, Maria L. Arbonés, Barbara Montserrat-Sentis, Michael B. Petersen, Sura Alwan, Raquel Rabionet, Hans-Henrik M. Dahl, Theofilos Iliades, Xavier Estivill, Torsten Schwede, Hamish S. Scott, Paolo Gasparini, Loretta Dougherty, Mario Vincenzo Di Iorio, Stylianos E. Antonarakis, Marie Wattenhofer, Marcello D'Amelio

Publikováno v: Journal of Molecular Medicine, Vol. 80, No 2 (2002) pp. 124-131

Two loci for nonsyndromic recessive deafness located on chromosome 21q22.3 have previously been reported, DFNB8 and DFNB10. Recently a gene which encodes a transmembrane serine protease, TMPRSS3 or ECHOS1, was found to be responsible for both the DFN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849aeb6ce6d9d16d9372437863169643
https://doi.org/10.1007/s00109-001-0310-6

Zobrazit plný text záznamu

Cloning of the TMPRSS2 Gene, Which Encodes a Novel Serine Protease with Transmembrane, LDLRA, and SRCR Domains and Maps to 21q22.3

Autor: Ariane Paoloni-Giacobino, Manuel C. Peitsch, Colette Rossier, Stylianos E. Antonarakis, Haiming Chen

Publikováno v: Genomics, Vol. 44, No 3 (1997) pp. 309-320

To contribute to the development of the transcription map of human chromosome 21 (HC21), we have used exon trapping from pools of HC21-specific cosmids. Using selected trapped exons, we have identified a novel gene (named TMPRSS2) that encodes a mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b65246c84aca67b9fe780f4657b0797
https://doi.org/10.1006/geno.1997.4845

Zobrazit plný text záznamu

Novel missense mutations of TMPRSS3 in two consanguineous Tunisian families with non-syndromic autosomal recessive deafness

Autor: Miano, Maria Giuseppina, Filippini, Francesco, Trujillo, Mariajos, Conte, Ivan, Lanzara, Carmela, Milln, Jos Maria, De Bernardo, Carmelilia, Grammatico, Barbara, Mangino, Massimo, Torrente, Isabella, Carrozzo, Romeo, Rinaldi, Ernesto, Ventruto, Valerio, Durso, Michele, Ayuso, Carmen, Ciccodicola, Alfredo, TESTA, Francesco, SIMONELLI, Francesca

Publikováno v: Human Mutation, Vol. 18, No 2 (2001) pp. 101-108

Recently the TMPRSS3 gene, which encodes a transmembrane serine protease, was found to be responsible for two non-syndromic recessive deafness loci located on human chromosome 21q22.3, DFNB8 and DFNB10. We found evidence for linkage to the DFNB8/10 l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffb81ccd60a8b7d8cbd9d5e065c00f7
https://pubmed.ncbi.nlm.nih.gov/11462234

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání