Inhibition of SARS-CoV 3CL protease by flavonoids

Autor: Seri Jo, Suwon Kim, Dong Hae Shin, Mi-Sun Kim

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 145-151 (2020)

There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required. Coronaviruses (CoVs) have been rising targets of some flav

Externí odkaz: https://doaj.org/article/aefa12f36a2c4d0ca540b63edf53a660

A study of Rose Bengal against a 2-keto-3-deoxy-d-manno-octulosonate cytidylyltransferase as an antibiotic candidate

Autor: Suwon Kim, Seri Jo, Mi-Sun Kim, Dong Hae Shin

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1414-1421 (2020)

Frequent occurrences of multi-drug resistance of pathogenic Gram-negative bacteria threaten human beings. The CMP-2-keto-3-deoxy-d-manno-octulosonic acid biosynthesis pathway is one of the new targets for antibiotic design. 2-Keto-3-deoxy-d-manno-oct

Externí odkaz: https://doaj.org/article/860fe50b334747dc9720c65abbb07d3e

A Study of 3CLpros as Promising Targets against SARS-CoV and SARS-CoV-2

Autor: Seri Jo, Suwon Kim, Jahyun Yoo, Mi-Sun Kim, Dong Hae Shin

Publikováno v: Microorganisms, Vol 9, Iss 4, p 756 (2021)

The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), results in serious chaos all over the world. In addition to the available vaccines, the development of treatments to cure COV

Externí odkaz: https://doaj.org/article/6d2d8175bd664776970bc45f207d69e3

Dimerization Tendency of 3CLpros of Human Coronaviruses Based on the X-ray Crystal Structure of the Catalytic Domain of SARS-CoV-2 3CLpro

Autor: Seri Jo, Hwa Young Kim, Dong Hae Shin, Mi-Sun Kim

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 5268

3CLpro of SARS-CoV-2 is a promising target for developing anti-COVID19 agents. In order to evaluate the catalytic activity of 3CLpros according to the presence or absence of the dimerization domain, two forms had been purified and tested. Enzyme kine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851db9b56aab43159d07d83d28f0d3b8
https://pubmed.ncbi.nlm.nih.gov/35563658

Inhibition of African swine fever virus protease by myricetin and myricitrin

Autor: Dong Hae Shin, Mi Sun Kim, Suwon Kim, Seri Jo

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1045-1049 (2020)
Journal of Enzyme Inhibition and Medicinal Chemistry

African swine fever (ASF) caused by the ASF virus (ASFV) is the most hazardous swine disease. Since a huge number of pigs have been slaughtered to avoid a pandemic spread, intense studies on the disease should be followed quickly. Recent studies repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd7b93f66d0d4849604144051fb1864
https://doi.org/10.1080/14756366.2020.1754813