Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Serhii Kostrikov"'
Autor:
Sophie B. Jensen, Ditte E. Jæhger, Elizabeth Serrano-Chávez, Hólmfríður R. Halldórsdóttir, Trine B. Engel, Jennifer S. Jørgensen, Unnur J. Björgvinsdóttir, Serhii Kostrikov, Marouschka J. Scheeper, Lars Ringgaard, Linda M. Bruun, Camilla Stavnsbjerg, Esben Christensen, Martin Bak, Julianna Thuroczy, Lajos Balogh, Andreas T. I. Jensen, Fredrik Melander, Andreas Kjaer, Jonas R. Henriksen, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer curing immune responses against heterogeneous solid cancers require that a coordinated immune activation is initiated in the antigen avid but immunosuppressive tumor microenvironment (TME). The plastic TME, and the poor systemic toler
Externí odkaz:
https://doaj.org/article/d50340662d0947fe879e809163698218
Autor:
Serhii Kostrikov, Kasper B. Johnsen, Thomas H. Braunstein, Johann M. Gudbergsson, Frederikke P. Fliedner, Elisabeth A. A. Obara, Petra Hamerlik, Anders E. Hansen, Andreas Kjaer, Casper Hempel, Thomas L. Andresen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Kostrikov et al. report a deficiency of transcardial perfusion in brain tumor vasculature, which leads to exaggeration of drug extravasation measurements. They then demonstrate how optical tissue clearing can help to overcome this limitation and prov
Externí odkaz:
https://doaj.org/article/351a278571824c1bab11d20eb4f1160f
Autor:
Sophie Jensen, Elizabeth Serrano-Chávez, Hólmfridur Halldórsdóttir, Trine Engel, Jennifer Jørgensen, Serhii Kostrikov, Marouschka Scheeper, Lars Ringgaard, Linda Bruun, Camilla Stavnsbjerg, Ditte Jæhger, Esben Christensen, Martin Bak, Julianna Thuroczy, Lajos Balogh, Andreas Jensen, Fredrik Melander, Andreas Kjaer, Jonas Henriksen, Anders Hansen, Thomas Andresen
Cancer curing immune responses against heterogeneous solid cancers require that a coordinated immune activation is initiated in the antigen avid but immunosuppressive tumor microenvironment (TME). The plastic, immunosuppressive TME, and the poor syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f7cae691685a4bcd0cd3e8691764c6a
https://doi.org/10.21203/rs.3.rs-2511064/v1
https://doi.org/10.21203/rs.3.rs-2511064/v1
Autor:
Esben Christensen, Johann Mar Gudbergsson, Thomas Lars Andresen, Andreas Kjaer, Kasper Bendix Johnsen, Serhii Kostrikov, Torben Moos, Meg Duroux
Publikováno v:
Gudbergsson, J M, Christensen, E, Kostrikov, S, Moos, T, Duroux, M, Kjær, A, Johnsen, K B & Andresen, T L 2020, ' Conventional Treatment of Glioblastoma Reveals Persistent CD44+ Subpopulations ', Molecular Neurobiology, vol. 57, no. 9, pp. 3943-3955 . https://doi.org/10.1007/s12035-020-02004-2
Glioblastoma (GBM) is the most frequent and devastating primary tumor of the central nervous system with a median survival of 12 to 15 months after diagnosis. GBM is highly difficult to treat due to its delicate location, inter- and intra-tumoral het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499806a691a2e1915453186e474b372c
https://doi.org/10.1007/s12035-020-02004-2
https://doi.org/10.1007/s12035-020-02004-2
Publikováno v:
Cancer and Metastasis Reviews. 39:959-968
Cancer treatment remains a challenge due to a high level of intra- and intertumoral heterogeneity and the rapid development of chemoresistance. In the brain, this is further hampered by the blood-brain barrier that reduces passive diffusion of drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559a9b654a589c33e399297d9c6d972e
https://doi.org/10.1007/s10555-020-09877-8
https://doi.org/10.1007/s10555-020-09877-8
Autor:
Andreas Kjaer, Petra Hamerlik, Casper Hempel, Johann Mar Gudbergsson, Thomas Hartig Braunstein, Thomas Lars Andresen, Frederikke P. Fliedner, Anders Elias Hansen, Elisabeth Anne Adanma Obara, Kasper Bendix Johnsen, Serhii Kostrikov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Kostrikov, S, Johnsen, K B, Braunstein, T H, Gudbergsson, J M, Fliedner, F P, Obara, E A A, Hamerlik, P, Hansen, A E, Kjaer, A, Hempel, C & Andresen, T L 2021, ' Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors ', Communications Biology, vol. 4, no. 1, 815 . https://doi.org/10.1038/s42003-021-02275-y
Communications Biology
Kostrikov, S, Johnsen, K B, Braunstein, T H, Gudbergsson, J M, Fliedner, F P, Obara, E A A, Hamerlik, P, Hansen, A E, Kjaer, A, Hempel, C & Andresen, T L 2021, ' Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors ', Communications Biology, vol. 4, no. 1, 815 . https://doi.org/10.1038/s42003-021-02275-y
Communications Biology
Precise methods for quantifying drug accumulation in brain tissue are currently very limited, challenging the development of new therapeutics for brain disorders. Transcardial perfusion is instrumental for removing the intravascular fraction of an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d75db0919169f33d6ad50743a48c86d
https://doi.org/10.1038/s42003-021-02275-y
https://doi.org/10.1038/s42003-021-02275-y
Publikováno v:
Cancer metastasis reviews. 39(3)
Cancer treatment remains a challenge due to a high level of intra- and intertumoral heterogeneity and the rapid development of chemoresistance. In the brain, this is further hampered by the blood-brain barrier that reduces passive diffusion of drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de95a9e669f5d8b934d36c4bc4eb3c53
https://pubmed.ncbi.nlm.nih.gov/32488404
https://pubmed.ncbi.nlm.nih.gov/32488404
Autor:
Johann Mar, Gudbergsson, Esben, Christensen, Serhii, Kostrikov, Torben, Moos, Meg, Duroux, Andreas, Kjær, Kasper Bendix, Johnsen, Thomas Lars, Andresen
Publikováno v:
Molecular neurobiology. 57(9)
Glioblastoma (GBM) is the most frequent and devastating primary tumor of the central nervous system with a median survival of 12 to 15 months after diagnosis. GBM is highly difficult to treat due to its delicate location, inter- and intra-tumoral het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da9c9b711adbf5f78ae716a739fd3da8
https://pubmed.ncbi.nlm.nih.gov/32632605
https://pubmed.ncbi.nlm.nih.gov/32632605
Autor:
Bjarne Winther Kristensen, Frederikke P. Fliedner, Anders Elias Hansen, Thomas Lars Andresen, Andreas Kjaer, Kasper Bendix Johnsen, Serhii Kostrikov, Nanna Humle, Christian Brøgger Stolberg, Meg Duroux, Gunna Christiansen, Johann Mar Gudbergsson
Publikováno v:
Gudbergsson, J M, Kostrikov, S, Johnsen, K B, Fliedner, F P, Stolberg, C B, Humle, N, Hansen, A E, Kristensen, B W, Christiansen, G, Kjær, A, Andresen, T L & Duroux, M 2019, ' A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response ', Experimental Cell Research, vol. 379, no. 1, pp. 73-82 . https://doi.org/10.1016/j.yexcr.2019.03.031
Gudbergsson, J M, Kostrikov, S, Johnsen, K B, Fliedner, F P, Stolberg, C B, Humle, N, Hansen, A E, Kristensen, B W, Christiansen, G, Kjaer, A, Andresen, T L & Duroux, M 2019, ' A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response ', Experimental Cell Research, vol. 379, no. 1, pp. 73-82 . https://doi.org/10.1016/j.yexcr.2019.03.031
Gudbergsson, J M, Kostrikov, S, Johnsen, K B, Fliedner, F P, Stolberg, C B, Humle, N, Hansen, A E, Kristensen, B W, Christiansen, G, Kjaer, A, Andresen, T L & Duroux, M 2019, ' A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response ', Experimental Cell Research, vol. 379, no. 1, pp. 73-82 . https://doi.org/10.1016/j.yexcr.2019.03.031
Glioblastoma multiforme (GBM) is the most common and malignant type of primary brain tumor and is characterized by its sudden onset and invasive growth into the brain parenchyma. The invasive tumor cells evade conventional treatments and are thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7eeb8c9c62433c6b213326321ce2f7
https://orbit.dtu.dk/en/publications/27fe9d52-12e5-4d80-962a-865ed667c6d4
https://orbit.dtu.dk/en/publications/27fe9d52-12e5-4d80-962a-865ed667c6d4
Autor:
Humberto Mestre, Anna L.R. Xavier, Helene Benveniste, Simon Sanggaard, Serhii Kostrikov, Albert Gjedde, Kristian Nygaard Mortensen, Hedok Lee
Publikováno v:
Nygaard Mortensen, K, Sanggaard, S, Mestre, H, Lee, H, Kostrikov, S, Xavier, A L R, Gjedde, A, Benveniste, H & Nedergaard, M 2019, ' Impaired Glymphatic Transport in Spontaneously Hypertensive Rats ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 39, no. 32, pp. 6365-6377 . https://doi.org/10.1523/JNEUROSCI.1974-18.2019
Mortensen, K N, Sanggaard, S, Mestre, H, Lee, H, Kostrikov, S, Xavier, A L R, Gjedde, A, Benveniste, H & Nedergaard, M 2019, ' Impaired Glymphatic Transport in Spontaneously Hypertensive Rats ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 39, no. 32, pp. 6365-6377 . https://doi.org/10.1523/JNEUROSCI.1974-18.2019
The Journal of Neuroscience
Mortensen, K N, Sanggaard, S, Mestre, H, Lee, H, Kostrikov, S, Xavier, A L R, Gjedde, A, Benveniste, H & Nedergaard, M 2019, ' Impaired Glymphatic Transport in Spontaneously Hypertensive Rats ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 39, no. 32, pp. 6365-6377 . https://doi.org/10.1523/JNEUROSCI.1974-18.2019
The Journal of Neuroscience
The glymphatic system is a brain-wide cerebrospinal fluid (CSF) transport system that utilizes the perivascular space for fast inflow of CSF. Arterial pulsations are a major driver of glymphatic CSF inflow, and hypertension that causes vascular patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5609b950c02dad2abdf488d51031144b
https://curis.ku.dk/ws/files/246825356/Impaired_Glymphatic_Transport_in_Spontaneously_Hypertensive_Rats.pdf
https://curis.ku.dk/ws/files/246825356/Impaired_Glymphatic_Transport_in_Spontaneously_Hypertensive_Rats.pdf