Výsledky vyhledávání - "Serhii, Zhersh"

Synthesis of Functionalized Bridged Bicyclic Sulfonamides with a Bridgehead Nitrogen Atom

Autor: Andrey A. Tolmachev, Oleksandr P. Blahun, Oleksandr O. Grygorenko, Serhii Zhersh, Heorhii Melnychenko, Yuliya O. Kuchkovska

Publikováno v: European Journal of Organic Chemistry. 2020:3261-3269

For many years, sulfonamide-derived drugs were dramatically prevailed by aromatic derivatives. However, the recently increased interest to synthesis of their aliphatic counterparts provides an access to yet underexplored parts of pharmaceutically rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9551bfdff1ccfd3cbea3dcb97f92f10d
https://doi.org/10.1002/ejoc.202000314

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Sulfonimidamides and Imidosulfuric Diamides: Compounds from an Underexplored Part of Biologically Relevant Chemical Space

Autor: Yuriy G. Shermolovich, Vadim M. Timoshenko, Oleksii Gavrylenko, Serhii Zhersh, Sergiy V. Zasukha, Andrey A. Tolmachev, Oleksandr O. Grygorenko, Valentyna O. Pivnytska

Publikováno v: Chemistry – A European Journal. 25:6928-6940

Two novel solid reagents-1-sulfonimidoyl- and 1-sulfamimidoyl-3-methylimidazolium derivatives-for the synthesis of sulfonimidamides and imidosulfuric diamides, respectively, were developed. It is shown that these reagents are very effective in substi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca17532c1dcbf0fa82e8abc785725bd9
https://doi.org/10.1002/chem.201900440

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Synthesis of spirocyclic β- and γ-sultams by one-pot reductive cyclization of cyanoalkylsulfonyl fluorides

Autor: Artem Yu. Cherepakha, Bohdan V. Vashchenko, Marian V. Gorichko, Kateryna O. Stepannikova, Serhii Zhersh, Yurii S. Moroz, Yulian M. Volovenko, Oleksandr O. Grygorenko

Publikováno v: European J Org Chem

One-pot intramolecular cyclization of novel sp(3)-enriched cyanoalkylsulfonyl fluorides into spirocyclic β- or γ-sultams is disclosed. The method relies on nitrile group reduction followed by sulfonylation of amino group thus formed upon mild condi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c7250faa34e84d8165158c3ef3e421
https://europepmc.org/articles/PMC8937022/

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Twisting and Turning the Sulfonamide Bond: A Synthetic, Quantum Chemical, and Crystallographic Study

Autor: Alexander B. Rozhenko, Dmitriy M. Volochnyuk, Oleksandr O. Grygorenko, Andrey A. Tolmachev, Serhii Zhersh, Oleksandr P. Blahun, Eduard B. Rusanov

Publikováno v: The Journal of organic chemistry. 85(8)

Structural restriction of the sulfonamide bond was used to design sultams with abnormal geometric parameters. Based on analysis of tertiary aliphatic sulfonamides published in the Cambridge crystallographic database, Paquette's sultams (i.e., bridged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4c51a73eec9624199de5638e4e3399
https://pubmed.ncbi.nlm.nih.gov/32162518

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Amino sulfonic acids, peptidosulfonamides and other related compounds

Autor: Oleksandr O. Grygorenko, Angelina V. Biitseva, Serhii Zhersh

Publikováno v: Tetrahedron. 74:1355-1421

A review with 636 references. The literature on saturated amino sulfonic acids with primary/secondary amino group and their derivatives from XIX century to 2016 is surveyed, focusing mainly on results published in the last two decades. Synthesis of s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b67a47db213b5710db184172ebaa8412
https://doi.org/10.1016/j.tet.2018.01.033

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