Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Serguei I Bannykh"'
Autor:
Christine Carico, Miriam Nuño, Debraj Mukherjee, Adam Elramsisy, Jocelynn Dantis, Jethro Hu, Jeremy Rudnick, John S Yu, Keith L Black, Serguei I Bannykh, Chirag G Patil
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33684 (2012)
Pre-temozolomide studies demonstrated that loss of the tumor suppressor gene PTEN held independent prognostic significance in GBM patients. We investigated whether loss of PTEN predicted shorter survival in the temozolomide era. The role of PTEN in t
Externí odkaz:
https://doaj.org/article/7ff0af6fb2614a7da8717a35022002d8
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figures S2, S3 and S4. Morphometric analysis of laminin-411 β1 chain (S2) and cancer stem cell markers (Notch-1, Notch-3, CD133, Nestin, and c-Myc; S3 and S4) on frozen sections of patient brain tumors. The expression of all markers significantly co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7954ae943f08a0594bc3fcdb183822b6
https://doi.org/10.1158/0008-5472.22423184.v1
https://doi.org/10.1158/0008-5472.22423184.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Video schematically shows the mechanism of glioblastoma treatment by laminin-411 inhibiting nanobioconjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1bcf1d94d457d8f4402664174692d4
https://doi.org/10.1158/0008-5472.22423166.v1
https://doi.org/10.1158/0008-5472.22423166.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figure S5. Binding of the nanobioconjugates to U87MG studied by flow cytometry is inhibited by human soluble TfR. This shows that the chimeric anti-human TfR antibody as part of nanobioconjugate fully retained its activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3255e723448b91bdefabf1741fac2b
https://doi.org/10.1158/0008-5472.22423181
https://doi.org/10.1158/0008-5472.22423181
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figure S10. Expression of Notch-1 and its ligand Jagged1 is significantly decreased in patient-derived glioblastoma cell lines with laminin-411 disruption by CRISPR/Cas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cdcf76995919f58fa3d462d85011ad
https://doi.org/10.1158/0008-5472.22423172.v1
https://doi.org/10.1158/0008-5472.22423172.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figures S8 and S9. Quantification of expression of laminin-411 β1 chain, its binding β1 integrin, Notch family members and other stem cell markers after nanobioconjugate treatment. All markers were significantly suppressed in treated tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c025739000157f1340b145f3c28041b
https://doi.org/10.1158/0008-5472.22423175.v1
https://doi.org/10.1158/0008-5472.22423175.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figures S6 and S7. Localization of labeled nanobioconjugates in tumors and biodistribution in brain. The nano drug is seen in the tumor parenchyma outside of blood vessels (S6) and preferentially accumulates in the tumor (peaks at 6 hr post-injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59040ca3ed6482f21e41148d0fe3e603
https://doi.org/10.1158/0008-5472.22423178.v1
https://doi.org/10.1158/0008-5472.22423178.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Tables S1, S2 and S3, and Figure S1. List of used antibodies (Table S1), and immunohistochemical expression of laminin-411 and laminin-421 in human gliomas of various grades (Tables S2 and S3). Expression of laminin-411 vs. laminin-421 increases with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9137908ec50a23363e4def7c22981d42
https://doi.org/10.1158/0008-5472.22423193
https://doi.org/10.1158/0008-5472.22423193
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Table S4. Physico-chemical characterization of used control and treatment nanobioconjugates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426cffb2ac89cc206a84c7ec1b3c3316
https://doi.org/10.1158/0008-5472.22423190
https://doi.org/10.1158/0008-5472.22423190
Autor:
Ekin Guney, Calixto-Hope G. Lucas, Kunwar Singh, Melike Pekmezci, Sebastian Fernandez-Pol, Kanish Mirchia, Angus Toland, Hannes Vogel, Serguei I Bannykh, Kristian T. Schafernak, Sanda Alexandrescu, Bret C. Mobley, Suzanne Z. Powell, Christian Davidson, Janna Neltner, Daniel R Boué, Eyas M Hattab, Sean P. Ferris, Robert S. Ohgami, James Louis Rubenstein, Andrew Wesley Bollen, Tarik Tihan, Arie Perry, David A. Solomon, Kwun Wah Wen
Publikováno v:
Blood Advances.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94472cbf83b86d826ca9511410165190
https://doi.org/10.1182/bloodadvances.2022009521
https://doi.org/10.1182/bloodadvances.2022009521