Possible roles of neuropeptide/transmitter and autoantibody modulation in emotional problems and aggression

Autor: Henning Værøy, Regina Skar-Fröding, Elin Hareton, Sergueï O. Fetissov

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

The theoretical foundations of understanding psychiatric disorders are undergoing changes. Explaining behaviour and neuroendocrine cell communication leaning towards immunology represents a different approach compared to previous models for understan

Externí odkaz: https://doaj.org/article/96583f3ead1240038dcac3bd86a7f34c

Immunoglobulin G is a natural oxytocin carrier which modulates oxytocin receptor signaling: relevance to aggressive behavior in humans

Autor: Henning Værøy, Emilie Lahaye, Christophe Dubessy, Magalie Benard, Marion Nicol, Yamina Cherifi, Saloua Takhlidjt, Jean-Luc do Rego, Jean-Claude do Rego, Nicolas Chartrel, Sergueï O. Fetissov

Publikováno v: Discover Mental Health, Vol 3, Iss 1, Pp 1-10 (2023)

Abstract Oxytocin is a neuropeptide produced mainly in the hypothalamus and secreted in the CNS and blood. In the brain, it plays a major role in promoting social interactions. Here we show that in human plasma about 60% of oxytocin is naturally boun

Externí odkaz: https://doaj.org/article/dfe8d24bd54e4fb89c8644670625c127

Role of gut bacteria in the physiological regulation of appetite and energy metabolism

Autor: Sergueï O. Fetissov

Publikováno v: Integrative Physiology. 2:21-32

The current “homeostatic theory” of appetite regulation assumes that alternation of hunger and satiety depends on energy balance in the host tissues encoded and transmitted to the brain by neuronal and hormonal signals. However, relatively low me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9baa94b530f2cec9658ae4092b59a3c6
https://doi.org/10.33910/2687-1270-2021-2-1-21-32

Host Starvation and Female Sex Influence Enterobacterial ClpB Production: A Possible Link to the Etiology of Eating Disorders

Autor: Nathalie Connil, Jonathan Breton, Camille Leclerc, Justine Jacquemot, Sergueï O. Fetissov, Marc G. J. Feuilloley, Pierre Déchelotte, Linda Yaker

Publikováno v: Microorganisms
Volume 8
Issue 4
Microorganisms, 2020, 8 (4), pp.530. ⟨10.3390/microorganisms8040530⟩
Microorganisms, Vol 8, Iss 530, p 530 (2020)
Microorganisms, MDPI, 2020, 8 (4), pp.530. ⟨10.3390/microorganisms8040530⟩

Altered signaling between gut bacteria and their host has recently been implicated in the pathophysiology of eating disorders, whereas the enterobacterial caseinolytic protease B (ClpB) may play a key role as an antigen mimetic of α-melanocyte-stimu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05379000940d974507fab077f2bd6178

Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice—a new potential probiotic for appetite and body weight management

Autor: Manon Dominique, Nicolas Lucas, Charlène Guérin, Pierre Déchelotte, Jean-Claude do Rego, Romain Legrand, Fatima Léon, Julie Rondeaux, Camille Deroissart, Grégory Lambert, S. Nobis, Saïda Azhar, Marie-Anne Le Solliec, Sergueï O. Fetissov, Nicolas Pons, S. Dusko Ehrlich

Publikováno v: International Journal of Obesity
International Journal of Obesity, Nature Publishing Group, 2020, ⟨10.1038/s41366-019-0515-9⟩
International Journal of Obesity (2005)

Background/objectives Based on the recent identification of E.coli heat shock protein ClpB as a mimetic of the anorexigenic α-melanocyte stimulating hormone (α-MSH), the objective of this study was to preclinically validate Hafnia alvei, a ClpB-pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27455290691fbe7cc4f0609c040001bb
https://hal-normandie-univ.archives-ouvertes.fr/hal-02474510