Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sergiy Dymov"'
Autor:
Stéphanie Grégoire, David Cheishvili, Mali Salmon-Divon, Sergiy Dymov, Lucas Topham, Virginie Calderon, Yoram Shir, Moshe Szyf, Laura S. Stone
Publikováno v:
PAIN Reports, Vol 6, Iss 4, p e960 (2021)
Abstract. Objective:. Determine if chronic low back pain (LBP) is associated with DNA methylation signatures in human T cells that will reveal novel mechanisms and potential therapeutic targets and explore the feasibility of epigenetic diagnostic mar
Externí odkaz:
https://doaj.org/article/834bfd8300a94aec92e6c133920966ed
Autor:
Yonghong Zhang, Sophie Petropoulos, Jinhua Liu, David Cheishvili, Rudy Zhou, Sergiy Dymov, Kang Li, Ning Li, Moshe Szyf
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-17 (2018)
Abstract Background The idea that changes to the host immune system are critical for cancer progression was proposed a century ago and recently regained experimental support. Results Herein, the hypothesis that hepatocellular carcinoma (HCC) leaves a
Externí odkaz:
https://doaj.org/article/02925f251cc0446dadb0038618baf59c
Autor:
Linda Booij, Moshe Szyf, Angela Carballedo, Eva-Maria Frey, Derek Morris, Sergiy Dymov, Farida Vaisheva, Victoria Ly, Ciara Fahey, James Meaney, Michael Gill, Thomas Frodl
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119061 (2015)
Serotonin plays an important role in the etiology of depression. Serotonin is also crucial for brain development. For instance, animal studies have demonstrated that early disruptions in the serotonin system affect brain development and emotion regul
Externí odkaz:
https://doaj.org/article/f17ed50322ad4a97ba898c28cd5aee92
Autor:
Antonio, Inserra, Antonella, Campanale, David, Cheishvili, Sergiy, Dymov, Amy, Wong, Nathalie, Marcal, Robert Andrew, Syme, Lorne, Taylor, Danilo, De Gregorio, Timothy E, Kennedy, Moshe, Szyf, Gabriella, Gobbi
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 119:110594
Psychedelic compounds elicit relief from mental disorders. However, the underpinnings of therapeutic improvement remain poorly understood. Here, we investigated the effects of repeated lysergic acid diethylamide (LSD) on whole-genome DNA methylation
Autor:
Sophie Petropoulos, Moshe Szyf, Ning Li, Yonghong Zhang, Kang Li, Rudy Zhou, Jinhua Liu, Sergiy Dymov, David Cheishvili
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-17 (2018)
Clinical Epigenetics
Clinical Epigenetics
Background The idea that changes to the host immune system are critical for cancer progression was proposed a century ago and recently regained experimental support. Results Herein, the hypothesis that hepatocellular carcinoma (HCC) leaves a molecula
Autor:
Michael Gill, Farida Vaisheva, Moshe Szyf, Derek Morris, Victoria Ly, Ciara Fahey, Linda Booij, Angela Carballedo, Sergiy Dymov, Thomas Frodl, James F. Meaney
Publikováno v:
Journal of Psychiatry and Neuroscience. 40:296-305
Background: The aim of the present study was to investigate the association of fMRI blood oxygen–level dependent (BOLD) reactivity with the level of epigenetic methylation of SLC6A4 in blood DNA from a sample of healthy participants and patients wi
Autor:
Sergiy Dymov, Moshe Szyf, Kevin Koenigs, Matthew Suderman, Stéphanie Grégoire, Maral Tajerian, Sebastian Alvarado, Laura S. Stone, Renaud Massart, Magali Millecamps
Publikováno v:
Scientific Reports
We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as
Autor:
Sergiy Dymov, Moshe Szyf, Benoit Labonté, Ana C. D'Alessio, Aya Sasaki, Patrick O. McGowan, Gustavo Turecki, Michael J. Meaney
Publikováno v:
Nature Neuroscience. 12:342-348
Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse alters HPA stress responses and increases the risk of suicide. We exami
Autor:
Sergiy Dymov, Victoria Ly, Farida Vaisheva, Ciara Fahey, Linda Booij, Thomas Frodl, Derek W. Morris, James F. Meaney, Michael Gill, Moshe Szyf, Eva-Maria Frey, Angela Carballedo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0119061 (2015)
PLoS ONE, Vol 10, Iss 3, p e0119061 (2015)
Serotonin plays an important role in the etiology of depression. Serotonin is also crucial for brain development. For instance, animal studies have demonstrated that early disruptions in the serotonin system affect brain development and emotion regul
Autor:
Ian C. G. Weaver, Frances A. Champagne, Moshe Szyf, Sergiy Dymov, Shelley E. Brown, Michael J. Meaney, Shakti Sharma
Publikováno v:
The Journal of Neuroscience. 25:11045-11054
Stress responses in the adult rat are programmed early in life by maternal care and associated with epigenomic marking of the hippocampal exon 17glucocorticoid receptor (GR) promoter. To examine whether such epigenetic programming is reversible in ad