Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sergiu P. Pasca"'
Autor:
Insoo Hyun, J. C. Scharf-Deering, Sarah Sullivan, John Dennis Aach, Paola Arlotta, Matthew L. Baum, George M. Church, Aaron Goldenberg, Henry T. Greely, Parastoo Khoshakhlagh, Richie E. Kohman, Melissa Lopes, Caroline Lowenthal, Aric Lu, Alex H. M. Ng, Sergiu P. Pasca, Bruna Paulsen, Martina Pigoni, Christopher T. Scott, David A. Silbersweig, Mark A. Skylar-Scott, Robert D. Truog, Jeantine E. Lunshof
Publikováno v:
Nature neuroscience. 25(11)
Autor:
Xiangling Meng, David Yao, Kevin W Kelley, Noah Reis, Mayuri V Thete, Shravanti Kulkarni, Michael C Bassik, Sergiu P Pasca
The assembly of cortical circuits involves the generation and migration of cortical interneurons from the ventral to the dorsal forebrain, which has been challenging to study in humans as these processes take place at inaccessible stages of late gest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe84ce20f7cf1fecc45f07f07415aee8
https://doi.org/10.1101/2022.09.06.506845
https://doi.org/10.1101/2022.09.06.506845
Publikováno v:
Molecular therapy. Methodsclinical development. 27
A limitation for rAAV-mediated gene transfer into the central nervous system (CNS) is the low penetration of vectors across the human blood-brain barrier (BBB). High doses of intravenously-delivered vector are required to reach the CNS, which has res
Autor:
Julien G. Roth, Lucia G. Brunel, Michelle S. Huang, Yueming Liu, Betty Cai, Sauradeep Sinha, Fan Yang, Sergiu P. Pașca, Sungchul Shin, Sarah C. Heilshorn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The biofabrication of three-dimensional (3D) tissues that recapitulate organ-specific architecture and function would benefit from temporal and spatial control of cell-cell interactions. Bioprinting, while potentially capable of achieving su
Externí odkaz:
https://doaj.org/article/ccf6740b904b407fbc10859b9fe7c252
Autor:
Romain Madelaine, Steven A. Sloan, Nina Huber, James H. Notwell, Louis C. Leung, Gemini Skariah, Caroline Halluin, Sergiu P. Paşca, Gill Bejerano, Mark A. Krasnow, Ben A. Barres, Philippe Mourrain
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1533-1542 (2017)
In the developing brain, neurons expressing VEGF-A and blood vessels grow in close apposition, but many of the molecular pathways regulating neuronal VEGF-A and neurovascular system development remain to be deciphered. Here, we show that miR-9 links
Externí odkaz:
https://doaj.org/article/afa35b6d422241ad859ef95b839bfc3f
Autor:
Natalia Gomez-Ospina, Georgia Panagiotakos, Thomas Portmann, Sergiu P Pasca, Dania Rabah, Agata Budzillo, Jean Pierre Kinet, Ricardo E Dolmetsch
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60526 (2013)
The C-terminus of the voltage-gated calcium channel Cav1.2 encodes a transcription factor, the calcium channel associated transcriptional regulator (CCAT), that regulates neurite extension and inhibits Cav1.2 expression. The mechanisms by which CCAT
Externí odkaz:
https://doaj.org/article/3c045b6804ce476589d73826acd0cd67