Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Sergio Scaccianoce"'
Publikováno v:
Biology, Vol 11, Iss 12, p 1785 (2022)
In 1981, Wylie Vale, Joachim Spiess, Catherine Rivier, and Jean Rivier reported on the characterization of a 41-amino-acid peptide from ovine hypothalamic extracts with high potency and intrinsic activity stimulating the secretion of adrenocorticotro
Externí odkaz:
https://doaj.org/article/ee65e137af734143830216f426a22cd6
Autor:
Paola Colucci, Alessia Santori, Luca Romanelli, Clemens Zwergel, Antonello Mai, Sergio Scaccianoce, Patrizia Campolongo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Amphetamine is a potent psychostimulant that increases brain monoamine levels. Extensive evidence demonstrated that norepinephrine is crucially involved in the regulation of memory consolidation for stressful experiences. Here, we investigated amphet
Externí odkaz:
https://doaj.org/article/35364ba6e57643208aa9bd6602dcc722
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
In vulnerable individuals, chronic and persistent stress is an established risk factor for disorders that are comorbid with Alzheimer’s disease (AD), such as hypertension, obesity and metabolic syndrome, and psychiatric disorders. There are no dise
Externí odkaz:
https://doaj.org/article/5efb1b3d393142448eba33672e57ed6c
Autor:
Vincenzo Mattei, Stefano Martellucci, Francesca Santilli, Valeria Manganelli, Tina Garofalo, Niccolò Candelise, Alessandra Caruso, Maurizio Sorice, Sergio Scaccianoce, Roberta Misasi
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169571 (2017)
The hippocampus is a vulnerable brain structure susceptible to damage during aging and chronic stress. Repeated exposure to opioids may alter the brain so that it functions normally when the drugs are present, thus, a prolonged withdrawal might lead
Externí odkaz:
https://doaj.org/article/fa7a4ba8d2634fe283c8256fb3689b38
Autor:
Francesco Matrisciano, Carla L Busceti, Domenico Bucci, Rosamaria Orlando, Alessandra Caruso, Gemma Molinaro, Irene Cappuccio, Barbara Riozzi, Roberto Gradini, Marta Motolese, Filippo Caraci, Agata Copani, Sergio Scaccianoce, Daniela Melchiorri, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicoletti
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16447 (2011)
The identification of mechanisms that mediate stress-induced hippocampal damage may shed new light into the pathophysiology of depressive disorders and provide new targets for therapeutic intervention. We focused on the secreted glycoprotein Dickkopf
Externí odkaz:
https://doaj.org/article/f7bf3abcdb084a838fe8882651ebf351
Autor:
Alessandra Caruso, Laura Ricceri, Angela Caruso, Ferdinando Nicoletti, Alessandra Gaetano, Sergio Scaccianoce
Publikováno v:
Behavioural Brain Research. 428:113891
Adolescence is a critical period for brain development. In most mammalian species, disturbances experienced during adolescence constitute a risk factor for several neuropsychiatric disorders. In this study, we compared the biochemical and behavioral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bbc71d0872b70a7f359144dd62a38a
https://doi.org/10.1016/j.bbr.2022.113891
https://doi.org/10.1016/j.bbr.2022.113891
Chronic stress induces maladaptive neural responses in several brain areas including hippocampus. It has been demonstrated that chronic stress exposure induced a downregulation of the putative presynaptic type 2 metabotropic glutamate (mGlu2) recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b1234520b06776a84e89ec6f9da8cf
http://hdl.handle.net/2108/213255
http://hdl.handle.net/2108/213255
Autor:
Patrick M. Colletti, Sergio Scaccianoce, Domenico Rubello, Alessandro Pala, Francesco Monteleone, Giulia Anna Follacchio, Mauro Liberatore
Objective Differentiation of infection from aseptic inflammation represents a major clinical issue. None of the commercially available compounds (labeled granulocytes, antigranulocyte antibodies, Ga-citrate, labeled immunoglobulin G, F-FDG) is capabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77917bae1a76c1b50ae8d83b8876957c
http://hdl.handle.net/11573/1320089
http://hdl.handle.net/11573/1320089
Autor:
Ferdinando Nicoletti, Rosamaria Orlando, Alessandra Caruso, Dalila Mango, Amira Saidi, Sergio Scaccianoce
Publikováno v:
Pharmacological research. 132
Prolonged stress predisposes susceptible individuals to a number of physiological disorders including cardiovascular disease, obesity and gastrointestinal disorders, as well as psychiatric and neurodegenerative disorders. Preclinical studies have sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e30572cd903374d691b0e596c2d05c
https://pubmed.ncbi.nlm.nih.gov/29689315
https://pubmed.ncbi.nlm.nih.gov/29689315
Autor:
Sonia Piccinin, Robert Nisticò, Benedetta Bigio, Carla Nasca, Sergio Scaccianoce, Bruce S. McEwen, Danielle Zelli
Publikováno v:
Proceedings of the National Academy of Sciences. 112:14960-14965
Excitatory amino acids play a key role in both adaptive and deleterious effects of stressors on the brain, and dysregulated glutamate homeostasis has been associated with psychiatric and neurological disorders. Here, we elucidate mechanisms of epigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192e6040cc80c2f0df63032fc4043c10
https://doi.org/10.1073/pnas.1516016112
https://doi.org/10.1073/pnas.1516016112