Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Sergio Rutella"'
Autor:
James O Lindsay, Daniel Hind, Lizzie Swaby, Hannah Berntsson, Mike Bradburn, Uday Bannur C, Jennifer Byrne, Christopher Clarke, Lauren Desoysa, Shahida Din, Richard Emsley, Gemma A Foulds, John Gribben, Christopher Hawkey, Peter M Irving, Peter Johnson, Majid Kazmi, Ellen Lee, Amanda Loban, Alan Lobo, Yashwant Mahida, Gordon Moran, Diana Papaioannou, Miles Parkes, Andrew Peniket, A Graham Pockley, Jack Satsangi, Sreedhar Subramanian, Simon Travis, Emily Turton, Ben Uttenthal, Sergio Rutella, John A Snowden
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 03 (2024)
Some text in this abstract has been reproduced from Lindsay J, Din S, Hawkey C, Hind D, Irving P, Lobo A, et al. OFR-9 An RCT of autologous stem-cell transplantation in treatment refractory Crohn’s disease (low-intensity therapy evaluation): ASTICl
Externí odkaz:
https://doaj.org/article/dc34c6a6762e4f599cb3fa947e2a353d
Autor:
Sergio Rutella, John Muth, Tom Leedom, Alexander Hamil, Basia Muz, Lena Luukkonen, Melissa Tran, Xia-Ha Li, Kristann Magee, Jayakmar Vadakekolathu, Ayman Kabakibi, Matthew L Cooper, Jan Davidson-Moncada
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/460623e1ece948da829ce14f696a534a
Autor:
Sergio Rutella, Amanda Cashen, John Muth, Jayakumar Vadakekolathu, Laura Arthur, Nitin Mahajan, Melissa Berrien-Elliott, Jan Davidson-Moncada, Todd Fehniger
Publikováno v:
HemaSphere, Vol 7, p e4299744 (2023)
Externí odkaz:
https://doaj.org/article/fa6cbd1740c443c294aaafb9c1b05c16
Autor:
Sergio Rutella, Jayakumar Vadakekolathu, Francesco Mazziotta, Stephen Reeder, Tung-On Yau, Rupkatha Mukhopadhyay, Benjamin Dickins, Heidi Altmann, Michael Kramer, Hanna A. Knaus, Bruce R. Blazar, Vedran Radojcic, Joshua F. Zeidner, Andrea Arruda, Bofei Wang, Hussein A. Abbas, Mark D. Minden, Sarah K. Tasian, Martin Bornhäuser, Ivana Gojo, Leo Luznik
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
Background Immune exhaustion and senescence are dominant dysfunctional states of effector T cells and major hurdles for the success of cancer immunotherapy. In the current study, we characterized how acute myeloid leukemia (AML) promotes the generati
Externí odkaz:
https://doaj.org/article/9b9ef0d762ff4c06a07a3be5dd99fa73
Autor:
Harshitha Shobha Manjunath MSc, Moza Al Khulaifi BSc, Heba Sidahmed MD, Adham Ammar MD, Jayakumar Vadakekolathu PhD, Sergio Rutella MD, Muneera Jassim Al-Mohannadi MD, Mamoun Elawad MD, William Mifsud MD, Adrian Charles MD, Cristina Maccalli PhD, Sara Tomei PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
The gene expression analysis of formalin-fixed paraffin-embedded (FFPE) tissues is often hampered by poor RNA quality, which results from the oxidation, cross-linking and other chemical modifications induced by the inclusion in paraffin. Yet, FFPE sa
Externí odkaz:
https://doaj.org/article/c2159ed4dd3044a4b8457e6205f6d71e
Autor:
Raquel Alves, Stephanie E. B. McArdle, Jayakumar Vadakekolathu, Ana Cristina Gonçalves, Paulo Freitas-Tavares, Amélia Pereira, Antonio M. Almeida, Ana Bela Sarmento-Ribeiro, Sergio Rutella
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Tumor cells have evolved complex strategies to escape immune surveillance, a process which involves NK cells and T lymphocytes, and various immunological factors. Indeed, tumor cells recruit immunosuppressive cells [including regu
Externí odkaz:
https://doaj.org/article/e73c20ff4cc64a2a894e0706d59184ef
Autor:
Ena Wang, Alessandra Cesano, Beatrix Kotlan, Mohan Karkada, Nicholas Tschernia, Aung Naing, Bruno Gomes, Anne Monette, Vésteinn Thórsson, Sergio Rutella, Vaios Karanikas, Michael A Cannarile, Justin Guinney, Giuseppe V Masucci, Els Meeusen, Daniel K Wells, Timothy L Wyant
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
The development of strongly predictive validated biomarkers is essential for the field of immuno-oncology (IO) to advance. The highly complex, multifactorial data sets required to develop these biomarkers necessitate effective, responsible data-shari
Externí odkaz:
https://doaj.org/article/093f0e8ec32a4d008042f3b582974250
Autor:
Ioana Plesca, Antje Tunger, Luise Müller, Rebekka Wehner, Xixi Lai, Marc-Oliver Grimm, Sergio Rutella, Michael Bachmann, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The tumor immune contexture plays a major role for the clinical outcome of patients. High densities of CD45RO+ T helper 1 cells and CD8+ T cells are associated with improved survival of patients with various cancer entities. In contrast, a higher fre
Externí odkaz:
https://doaj.org/article/1bfe7fe5c6024be1963558088d27f31e
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Tumors employ strategies to escape immune control. The principle aim of most cancer immunotherapies is to restore effective immune surveillance. Among the different processes regulating immune escape, tumor microenvironment-associated soluble factors
Externí odkaz:
https://doaj.org/article/401a2f15cf6542f3a42fe83cd6b30032
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 16, Iss , Pp 77-87 (2018)
The field of machine learning has allowed researchers to generate and analyse vast amounts of data using a wide variety of methodologies. Artificial Neural Networks (ANN) are some of the most commonly used statistical models and have been successful
Externí odkaz:
https://doaj.org/article/9e8490d8fff142bebc3fd776f69f988c