Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Sergio Ruiz-Llorente"'
Autor:
Jesus Garcia-Donas, Diego Martínez-Urbistondo, Kyra Velázquez Kennedy, Paula Villares, Arántzazu Barquin, Andrea Dominguez, Juan Francisco Rodriguez-Moreno, Elena Caro, Rafael Suarez del Villar, Estanislao Nistal-Villan, Monica Yagüe, Maria Ortiz, Maria Barba, Sergio Ruiz-Llorente, Miguel Quiralte, Massimiliano Zanin, Cristina Rodríguez, Paloma Navarro, Pedro Berraondo, Rodrigo Madurga
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundManaging the inflammatory response to SARS-Cov-2 could prevent respiratory insufficiency. Cytokine profiles could identify cases at risk of severe disease.MethodsWe designed a randomized phase II clinical trial to determine whether the comb
Externí odkaz:
https://doaj.org/article/3ee849271a0c45228839d81a26042e68
Autor:
Cristina Montero‐Conde, Luis Javier Leandro‐García, Ángel M. Martínez‐Montes, Paula Martínez, Francisco J. Moya, Rocío Letón, Eduardo Gil, Natalia Martínez‐Puente, Sonsoles Guadalix, Maria Currás‐Freixes, Laura García‐Tobar, Carles Zafon, Mireia Jordà, Garcilaso Riesco‐Eizaguirre, Patricia González‐García, María Monteagudo, Rafael Torres‐Pérez, Veronika Mancikova, Sergio Ruiz‐Llorente, Manuel Pérez‐Martínez, Guillermo Pita, Juan Carlos Galofré, Anna Gonzalez‐Neira, Alberto Cascón, Cristina Rodríguez‐Antona, Diego Megías, María A. Blasco, Eduardo Caleiras, Sandra Rodríguez‐Perales, Mercedes Robledo
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Background Comprehensive molecular studies on tumours are needed to delineate immortalization process steps and identify sensitive prognostic biomarkers in thyroid cancer. Methods and Results In this study, we extensively characterize telomere‐rela
Externí odkaz:
https://doaj.org/article/50de3fcc7b624a41bff4004a50893619
Autor:
Luis Bote-Curiel, Sergio Ruiz-Llorente, Sergio Munoz-Romero, Monica Yague-Fernandez, Arantzazu Barquin, Jesus Garcia-Donas, Jose Luis Rojo-Alvarez
Publikováno v:
IEEE Access, Vol 9, Pp 25959-25972 (2021)
Ovarian cancer (OC) is the second most common gynecological malignancy and the gynecological tumor with the worst prognosis. To try to improve this situation, Data Science technologies could be a useful tool to help clinicians to know more about the
Externí odkaz:
https://doaj.org/article/8bb87a2d21eb4942a609f2c862f38042
Autor:
Luis Bote-Curiel, Sergio Ruiz-Llorente, Sergio Munoz-Romero, Monica Yague-Fernandez, Arantzazu Barquin, Jesus Garcia-Donas, Jose Luis Rojo-Alvarez
Publikováno v:
IEEE Access, Vol 9, Pp 58034-58051 (2021)
Developments of richer integrative analysis methods for oncological studies are needed for efficiently leveraging the amount of clinical and genetic data available to provide the clinicians with better information. However, analyses of this nature of
Externí odkaz:
https://doaj.org/article/5b73143ec7904fb39024b9024e315c53
Autor:
Veronica Garcia-Carpizo, Sergio Ruiz-Llorente, Jacinto Sarmentero, Osvaldo Graña-Castro, David G. Pisano, Maria J. Barrero
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background The reported antitumor activity of the BET family bromodomain inhibitors has prompted the development of inhibitors against other bromodomains. However, the human genome encodes more than 60 different bromodomains and most of them
Externí odkaz:
https://doaj.org/article/1cadd9631f0b4b4fbc0049e7261406dc
Autor:
Iñigo Landa, Cesar Boullosa, Lucía Inglada-Pérez, Ana Sastre-Perona, Susana Pastor, Antonia Velázquez, Veronika Mancikova, Sergio Ruiz-Llorente, Francesca Schiavi, Ricard Marcos, Nuria Malats, Giuseppe Opocher, Ramon Diaz-Uriarte, Pilar Santisteban, Alfonso Valencia, Mercedes Robledo
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74765 (2013)
Papillary Thyroid Cancer (PTC) is a heterogeneous and complex disease; susceptibility to PTC is influenced by the joint effects of multiple common, low-penetrance genes, although relatively few have been identified to date. Here we applied a rigorous
Externí odkaz:
https://doaj.org/article/4c1f6195c3314c3c9d7f014736d1cc8e
Autor:
Iñigo Landa, Cesar Boullosa, Lucía Inglada-Pérez, Ana Sastre-Perona, Susana Pastor, Antonia Velázquez, Veronika Mancikova, Sergio Ruiz-Llorente, Francesca Schiavi, Ricard Marcos, Nuria Malats, Giuseppe Opocher, Ramon Diaz-Uriarte, Pilar Santisteban, Alfonso Valencia, Mercedes Robledo
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/a6a04b4068b148fa95548eb42e330427
Autor:
Iñigo Landa, Sergio Ruiz-Llorente, Cristina Montero-Conde, Lucía Inglada-Pérez, Francesca Schiavi, Susanna Leskelä, Guillermo Pita, Roger Milne, Javier Maravall, Ignacio Ramos, Víctor Andía, Paloma Rodríguez-Poyo, Antonino Jara-Albarrán, Amparo Meoro, Cristina del Peso, Luis Arribas, Pedro Iglesias, Javier Caballero, Joaquín Serrano, Antonio Picó, Francisco Pomares, Gabriel Giménez, Pedro López-Mondéjar, Roberto Castello, Isabella Merante-Boschin, Maria-Rosa Pelizzo, Didac Mauricio, Giuseppe Opocher, Cristina Rodríguez-Antona, Anna González-Neira, Xavier Matías-Guiu, Pilar Santisteban, Mercedes Robledo
Publikováno v:
PLoS Genetics, Vol 5, Iss 9, p e1000637 (2009)
In order to identify genetic factors related to thyroid cancer susceptibility, we adopted a candidate gene approach. We studied tag- and putative functional SNPs in genes involved in thyroid cell differentiation and proliferation, and in genes found
Externí odkaz:
https://doaj.org/article/2bba8d0b28df44c4b674e2659f938350
Autor:
James A. Fagin, Neal Rosen, Ronald A. Ghossein, Mabel Ryder, Eric J. Sherman, Agnes Viale, Jeffrey A. Knauf, Jose M. Dominguez, Sergio Ruiz-Llorente, Cristina Montero-Conde
Supplementary Figure S5 PDF file - 32K, PLX4032 decreases occupancy of the HER3 gene promoter in SW1736 thyroid cancer cells. A, CtBP1 or CtBP2 chromatin immunoprecipitation assays were performed in SW1736 cells treated with or without 2 ��M PLX4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0200ad97f0ee46a8ebc5c53106262ce5
https://doi.org/10.1158/2159-8290.22529378.v1
https://doi.org/10.1158/2159-8290.22529378.v1
Autor:
Maria J. Barrero, Ana González-Corpas, Jacinto Sarmentero, Sergio Ruiz-Llorente, Veronica Garcia-Carpizo
GSEA enrichments for genes changing expression after JQ or CBP30 treatments. (a) Top reactome pathways significantly enriched in upregulated or downregulated genes. Black boxes indicate significant enrichment with P-value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069d75b21cae3edc6c027415a016a69b
https://doi.org/10.1158/1541-7786.22515885
https://doi.org/10.1158/1541-7786.22515885