Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Sergio Pedraza"'
Autor:
Emilia Alors‐Pérez, Ricardo Blázquez‐Encinas, María Trinidad Moreno‐Montilla, Víctor García‐Vioque, Juan Manuel Jiménez‐Vacas, Andrea Mafficini, Iranzu González‐Borja, Claudio Luchini, Juan M. Sánchez‐Hidalgo, Marina E. Sánchez‐Frías, Sergio Pedraza‐Arevalo, Antonio Romero‐Ruiz, Rita T. Lawlor, Antonio Viúdez, Manuel D. Gahete, Aldo Scarpa, Álvaro Arjona‐Sánchez, Raúl M. Luque, Alejandro Ibáñez‐Costa, Justo P. Castaño
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2524-2540 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, characterized by late diagnosis and poor treatment response. Surgery is the only curative approach, only available to early‐diagnosed patients. Current therapies have limited effect
Externí odkaz:
https://doaj.org/article/de947d6fca6d49f9911a2528b10949ca
Autor:
Ricardo Blázquez-Encinas, Víctor García-Vioque, Teresa Caro-Cuenca, María Trinidad Moreno-Montilla, Federica Mangili, Emilia Alors-Pérez, Sebastian Ventura, Aura D. Herrera-Martínez, Paula Moreno-Casado, Marco A. Calzado, Ángel Salvatierra, María A. Gálvez-Moreno, Lynnette Fernandez-Cuesta, Matthieu Foll, Raúl M. Luque, Nicolas Alcala, Sergio Pedraza-Arevalo, Alejandro Ibáñez-Costa, Justo P. Castaño
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Lung neuroendocrine neoplasms (LungNENs) comprise a heterogeneous group of tumors ranging from indolent lesions with good prognosis to highly aggressive cancers. Carcinoids are the rarest LungNENs, display low to intermediate mali
Externí odkaz:
https://doaj.org/article/d52791785b0348c3acabc1dd11422717
Autor:
Emilia Alors-Pérez, Sergio Pedraza-Arevalo, Ricardo Blázquez-Encinas, María Trinidad Moreno-Montilla, Víctor García-Vioque, Inmaculada Berbel, Raúl M. Luque, Bruno Sainz, Alejandro Ibáñez-Costa, Justo P. Castaño
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers worldwide, mainly due to its late diagnosis and lack of effective therapies, translating into a low 5-year 12% survival rate, despite extensive clinical efforts t
Externí odkaz:
https://doaj.org/article/a84214f7f90144bfaa84a7594e4529bf
Autor:
Emilia Alors-Pérez, Sergio Pedraza-Arevalo, Ricardo Blázquez-Encinas, Víctor García-Vioque, Antonio Agraz-Doblas, Elena M. Yubero-Serrano, Marina E. Sánchez-Frías, Raquel Serrano-Blanch, María Ángeles Gálvez-Moreno, Francisco Gracia-Navarro, Manuel D. Gahete, Álvaro Arjona-Sánchez, Raúl M. Luque, Alejandro Ibáñez-Costa, Justo P. Castaño
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102090- (2024)
Pancreatic neuroendocrine tumors (PanNETs) comprise a heterogeneous group of tumors with growing incidence. Recent molecular analyses provided a precise picture of their genomic and epigenomic landscape. Splicing dysregulation is increasingly regarde
Externí odkaz:
https://doaj.org/article/46b3eb5e3ec743c68155cde95dd29e80
Autor:
Sergio Pedraza‐Arevalo, Alejandro Ibáñez‐Costa, Ricardo Blázquez‐Encinas, Miguel R. Branco, Mari C. Vázquez‐Borrego, Aura D. Herrera‐Martínez, Eva Venegas‐Moreno, Raquel Serrano‐Blanch, Álvaro Arjona‐Sánchez, María A. Gálvez‐Moreno, Marta Korbonits, Alfonso Soto‐Moreno, Manuel D. Gahete, Marika Charalambous, Raúl M. Luque, Justo P. Castaño
Publikováno v:
Molecular Oncology, Vol 16, Iss 3, Pp 764-779 (2022)
Somatostatin receptor subtype 5 (SST5) is an emerging biomarker and actionable target in pituitary (PitNETs) and pancreatic (PanNETs) neuroendocrine tumors. Transcriptional and epigenetic regulation of SSTR5 gene expression and mRNA biogenesis is poo
Externí odkaz:
https://doaj.org/article/b32f6c1bca5844c5a89dc0ab9f39ab12
Autor:
Emilia Alors-Perez, Ricardo Blázquez-Encinas, Sonia Alcalá, Cristina Viyuela-García, Sergio Pedraza-Arevalo, Vicente Herrero-Aguayo, Juan M. Jiménez-Vacas, Andrea Mafficini, Marina E. Sánchez-Frías, María T. Cano, Fernando Abollo-Jiménez, Juan A. Marín-Sanz, Pablo Cabezas-Sainz, Rita T. Lawlor, Claudio Luchini, Laura Sánchez, Juan M. Sánchez-Hidalgo, Sebastián Ventura, Laura Martin-Hijano, Manuel D. Gahete, Aldo Scarpa, Álvaro Arjona-Sánchez, Alejandro Ibáñez-Costa, Bruno Sainz, Raúl M. Luque, Justo P. Castaño
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, requiring novel treatments to target both cancer cells and cancer stem cells (CSCs). Altered splicing is emerging as both a novel cancer hallmark and an attractive
Externí odkaz:
https://doaj.org/article/2e57a0d7fd7f42d6a9f88e1c0cae6aca
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101656- (2022)
Summary: Human induced pluripotent stem cells (hiPSCs) and organoids are important for modeling human development and disease in vitro. In this study, we describe a protocol to differentiate hiPSC toward pancreatic progenitor (PP) organoids and beta-
Externí odkaz:
https://doaj.org/article/6e78da5a9a6242bfaa92ef7748d07f91
Autor:
Yiraldine Herrera-Martínez, María José Contreras González, Sergio Pedraza-Arévalo, Maria del Carmen Guerrero Martínez, Ángela Rodrigo Martínez, Alberto González Menchen, Maria Angeles Blanco Molina, Maria Angeles Gálvez-Moreno, Alberto L. Moreno-Vega, Raúl M. Luque, Aura D. Herrera-Martínez
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Hypercalcemia is a common complication in cancer patients Mainly caused by Parathyroid hormone-related protein (PTHrP) secretion and metastasis. Calcitriol secretion is a rare source of hypercalcemia in solid tumors, especially in gastrointestinal st
Externí odkaz:
https://doaj.org/article/ff8de20aef5f4be58a6fcfba92e81d16
Autor:
Juan M. Jiménez-Vacas, Vicente Herrero-Aguayo, Antonio J. Montero-Hidalgo, Enrique Gómez-Gómez, Antonio C. Fuentes-Fayos, Antonio J. León-González, Prudencio Sáez-Martínez, Emilia Alors-Pérez, Sergio Pedraza-Arévalo, Teresa González-Serrano, Oscar Reyes, Ana Martínez-López, Rafael Sánchez-Sánchez, Sebastián Ventura, Elena M. Yubero-Serrano, María J. Requena-Tapia, Justo P. Castaño, Manuel D. Gahete, Raúl M. Luque
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: Dysregulation of splicing variants (SVs) expression has recently emerged as a novel cancer hallmark. Although the generation of aberrant SVs (e.g. AR-v7/sst5TMD4/etc.) is associated to prostate-cancer (PCa) aggressiveness and/or castratio
Externí odkaz:
https://doaj.org/article/2ef43292c5e645488d2beac6b2a5afe9
Autor:
Moreno Montilla Maria Trinidad, Vioque Victor Garcia, Encinas Rey Ricardo Blazquez, Martinez Montes Angel Mario, Emilia Alors-Perez, Federica Mangili, Sergio Pedraza-Arevalo, Mercedes Robledo, Justo P. Castano, Costa Alejandro Ibanez
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79bed4badbef04ac29dd00aa82fe41a
https://doi.org/10.1530/endoabs.90.p109
https://doi.org/10.1530/endoabs.90.p109