Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Sergio P A Toledo"'
Genotype and phenotype landscape of MEN2 in 554 medullary thyroid cancer patients: the BrasMEN study
Autor:
Rui M B Maciel, Cleber P Camacho, Lígia V M Assumpção, Natassia E Bufalo, André L Carvalho, Gisah A de Carvalho, Luciana A Castroneves, Francisco M de Castro Jr, Lucieli Ceolin, Janete M Cerutti, Rossana Corbo, Tânia M B L Ferraz, Carla V Ferreira, M Inez C França, Henrique C R Galvão, Fausto Germano-Neto, Hans Graf, Alexander A L Jorge, Ilda S Kunii, Márcio W Lauria, Vera L G Leal, Susan C Lindsey, Delmar M Lourenço Jr, Léa M Z Maciel, Patrícia K R Magalhães, João R M Martins, M Cecília Martins-Costa, Gláucia M F S Mazeto, Anelise I Impellizzeri, Célia R Nogueira, Edenir I Palmero, Cencita H C N Pessoa, Bibiana Prada, Débora R Siqueira, Maria Sharmila A Sousa, Rodrigo A Toledo, Flávia O F Valente, Fernanda Vaisman, Laura S Ward, Shana S Weber, Rita V Weiss, Ji H Yang, Magnus R Dias-da-Silva, Ana O Hoff, Sergio P A Toledo, Ana L Maia
Publikováno v:
Endocrine Connections, Vol 8, Iss 3, Pp 289-298 (2019)
Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant genetic disease caused by RET gene germline mutations that is characterized by medullary thyroid carcinoma (MTC) associated with other endocrine tumors. Several reports have demonstr
Externí odkaz:
https://doaj.org/article/37d0d78e06b24b48bb6c7725c95f14cc
Autor:
Giovanny Fuentevilla-Álvarez, María Elena Soto, Yazmín Estela Torres-Paz, Sergio Enrique Meza-Toledo, Gilberto Vargas-Alarcón, Nadia González-Moyotl, Israel Pérez-Torres, Linaloe Manzano-Pech, Ana Maria Mejia, Claudia Huesca-Gómez, Ricardo Gamboa
Publikováno v:
Biomolecules & Biomedicine, Vol 24, Iss 2 (2024)
Marfan syndrome (MFS) is a multisystem genetic disorder with over 3000 mutations described in the fibrillin 1 (FBN1) gene. Like MFS, other connective tissue disorders also require a deeper understanding of the phenotype-genotype relationship due to t
Externí odkaz:
https://doaj.org/article/cf76f7eaefc648259f0126ae61d2895a
Autor:
Giovanny Fuentevilla-Álvarez, Claudia Huesca-Gómez, Yazmín Estela Paz-Torres, Nadia González-Moyotl, María Elena Soto, José Antonio García-Valdivia, Reyna-Sámano, Martín Martínez-Rosas, Sergio Enrique Meza-Toledo, Ricardo Gamboa
Publikováno v:
Archives of Endocrinology and Metabolism, Vol 68 (2024)
ABSTRACT Objective: Recent studies have shown a relationship between adipose tissue and coronary artery disease (CAD). The ABCA1 transporter regulates cellular cholesterol content and reverses cholesterol transport. The aim of this study was to deter
Externí odkaz:
https://doaj.org/article/2498d5cb659c4eab8a41aeb33dfc36f0
Autor:
Mario Perez-Medina, Jose S. Lopez-Gonzalez, Jesus J. Benito-Lopez, Santiago Ávila-Ríos, Maribel Soto-Nava, Margarita Matias-Florentino, Alfonso Méndez-Tenorio, Miriam Galicia-Velasco, Rodolfo Chavez-Dominguez, Sergio E. Meza-Toledo, Dolores Aguilar-Cazares
Publikováno v:
Cancers, Vol 16, Iss 13, p 2490 (2024)
Lung adenocarcinoma is the most prevalent form of lung cancer, and drug resistance poses a significant obstacle in its treatment. This study aimed to investigate the overexpression of long non-coding RNAs (lncRNAs) as a mechanism that promotes intrin
Externí odkaz:
https://doaj.org/article/8fa8c20757be4b0db68e16321c410e83
Autor:
Giovanny Fuentevilla-Alvarez, María Elena Soto, Gustavo Jaziel Robles-Herrera, Gilberto Vargas-Alarcón, Reyna Sámano, Sergio Enrique Meza-Toledo, Claudia Huesca-Gómez, Ricardo Gamboa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7078 (2024)
Type 2 diabetes mellitus (T2DM) is associated with various complications, including diabetic foot, which can lead to significant morbidity and mortality. Non-healing foot ulcers in diabetic patients are a major risk factor for infections and amputati
Externí odkaz:
https://doaj.org/article/4f931aea2894444485df427187d94acb
Autor:
Maria Elena Soto, Giovanny Fuentevilla-Alvarez, Solange Gabriela Koretzky, Gilberto Vargas-Alarcón, Yazmín Estela Torres-Paz, Sergio Enrique Meza-Toledo, Israel Pérez-Torres, Claudia Huesca-Gómez, Ricardo Gamboa
Publikováno v:
Biomolecules & Biomedicine, Vol 23, Iss 6 (2023)
Marfan syndrome (MFS) is an inherited connective tissue disorder. As the spinal growth depends on delicate balance of forces, conditions that affect musculoskeletal matrix often lead to spinal deformities. A large cross-sectional study revealed a 63%
Externí odkaz:
https://doaj.org/article/3ffc77fef562425b908737ffa922939a
Autor:
José Melesio Cristóbal-Luna, María Angélica Mojica-Villegas, Sergio Enrique Meza-Toledo, Yuliana García-Martínez, Angélica Pérez-Juárez, Germán Chamorro-Cevallos
Publikováno v:
Life, Vol 13, Iss 8, p 1714 (2023)
Antiepileptic drugs affect embryonic development when administered during pregnancy, generating severe alterations, such as as cleft lip, spina bifida, heart abnormalities, or neuronal alterations. The compound DL-4-hydroxy-4-phenylhexanamide (DL-HEP
Externí odkaz:
https://doaj.org/article/f71ef62bdc924686b664867563993228
Autor:
Elayne Irene Becerra-Báez, Sergio Enrique Meza-Toledo, Paola Muñoz-López, Luis Fernando Flores-Martínez, Karla Fraga-Pérez, Kevin Jorge Magaño-Bocanegra, Uriel Juárez-Hernández, Armando Alfredo Mateos-Chávez, Rosendo Luria-Pérez
Publikováno v:
Cancers, Vol 14, Iss 17, p 4224 (2022)
Over a century ago, bacterial extracts were found to be useful in cancer therapy, but this treatment modality was obviated for decades. Currently, in spite of the development and advances in chemotherapies and radiotherapy, failure of these conventio
Externí odkaz:
https://doaj.org/article/64b614851bed4dbdb1926fc43c71aeb1
Autor:
Elisangela P S Quedas, Antonio M. Lerario, Sergio P. A. Toledo, Viviane C. Longuini, Betsaida Urtremari, Delmar M. Lourenço, Fábio Luiz de Menezes Montenegro, Alexander A. L. Jorge, Tomoko Sekiya, Stephen J. Marx, Lucas Santos de Santana, Rodrigo A. Toledo, Rafael Arrabaça Carvalho
Publikováno v:
European Journal of Endocrinology. 179:391-407
Background Loss-of-function germline MEN1 gene mutations account for 75–95% of patients with multiple endocrine neoplasia type 1 (MEN1). It has been postulated that mutations in non-coding regions of MEN1 might occur in some of the remaining patien
Autor:
Karine Bitencourt Rodrigues, Delmar M. Lourenço, Climerio Pereira do Nascimento, Marília D'Elboux Guimarães Brescia, Sérgio Samir Arap, André Fernandes d’Alessandro, Fábio Luiz de Menezes Montenegro, Sergio P. A. Toledo
Publikováno v:
Journal of the Endocrine Society
Background: Surgery is the elective therapy for primary hyperparathyroidism (HPT) in patients with multiple endocrine neoplasia type 1 (MEN1). As MEN1 mutation carriers invariably will develop HPT up to 50 years, the annual periodic screening have al