Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Sergio Marco"'
Autor:
Leonardo D. Garma, Lisbeth Harder, Juan M. Barba-Reyes, Sergio Marco Salas, Mónica Díez-Salguero, Mats Nilsson, Alberto Serrano-Pozo, Bradley T. Hyman, Ana B. Muñoz-Manchado
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Deciphering the striatal interneuron diversity is key to understanding the basal ganglia circuit and to untangling the complex neurological and psychiatric diseases affecting this brain structure. We performed snRNA-seq and spatial transcrip
Externí odkaz:
https://doaj.org/article/728e375820ee48959c617e3c85e173d2
Autor:
Nicholas Donnelly, Adam Cunningham, Sergio Marco Salas, Matthew Bracher-Smith, Samuel Chawner, Jan Stochl, Tamsin Ford, F. Lucy Raymond, Valentina Escott-Price, Marianne B. M. van den Bree
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Genomic conditions can be associated with developmental delay, intellectual disability, autism spectrum disorder, and physical and mental health symptoms. They are individually rare and highly variable in presentation, which limit
Externí odkaz:
https://doaj.org/article/036c1f415aca40a8b027e201c1374247
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b6db719a64854f4ca0bb080659c88c0b
Autor:
Simon Collett, Linda Earnest, Julio Carrera Montoya, Melissa A. Edeling, Ashley Yap, Chinn Yi Wong, Dale Christiansen, Jason Roberts, Jamie Mumford, Valerie Lecouturier, Vincent Pavot, Sergio Marco, Joon Keit Loi, Cameron Simmons, Shivali A. Gulab, Jason M. Mackenzie, Aaron Elbourne, Paul A. Ramsland, Garth Cameron, Dhiraj Hans, Dale I. Godfrey, Joseph Torresi
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The development of virus-like particle (VLP) based vaccines for human papillomavirus, hepatitis B and hepatitis E viruses represented a breakthrough in vaccine development. However, for dengue and COVID-19, technical complications, such as an incompl
Externí odkaz:
https://doaj.org/article/db5da8de105e44ddb37fe0edcbcb6989
Autor:
Alban Guesdon-Vennerie, Patrick Couvreur, Fatoumia Ali, Frédéric Pouzoulet, Christophe Roulin, Immaculada Martínez-Rovira, Guillaume Bernadat, François-Xavier Legrand, Claudie Bourgaux, Cyril Lucien Mazars, Sergio Marco, Sylvain Trépout, Simona Mura, Sébastien Mériaux, Guillaume Bort
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Triggered therapeutics are of interest but currently suffer from limited penetration depth of light sources. Here, the authors report on the development of a system, called radioswitch, that uses ionising irradiation to switch an azobenzene modified
Externí odkaz:
https://doaj.org/article/3dadd7cbd6c84fc4b86cbcac939a2b9b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Highly multiplexed spatial mapping of transcripts within tissues allows for investigation of the transcriptomic and cellular diversity of mammalian organs previously unseen. Here we explore a direct RNA (dRNA) detection approach incorporatin
Externí odkaz:
https://doaj.org/article/5cd61bf6b53a4cd98703411e3b0aa8e9
Autor:
Sergio Marco Salas, Xiao Yuan, Christer Sylven, Mats Nilsson, Carolina Wählby, Gabriele Partel
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 8, p e1010366 (2022)
With the emergence of high throughput single cell techniques, the understanding of the molecular and cellular diversity of mammalian organs have rapidly increased. In order to understand the spatial organization of this diversity, single cell data is
Externí odkaz:
https://doaj.org/article/6dcd79603c5c473eb053649c29d706ec
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background A range of spatially resolved transcriptomic methods has recently emerged as a way to spatially characterize the molecular and cellular diversity of a tissue. As a consequence, an increasing number of computational techniques are
Externí odkaz:
https://doaj.org/article/4a4930e29a6d43f7b2bed1b8c14c92a5
Autor:
Anastasia Magoulopoulou, Xiaoyan Qian, Todia Pediatama Setiabudiawan, Sergio Marco Salas, Chika Yokota, Martin E. Rottenberg, Mats Nilsson, Berit Carow
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mycobacterium tuberculosis (Mtb) bacilli are the causative agent of tuberculosis (TB), a major killer of mankind. Although it is widely accepted that local interactions between Mtb and the immune system in the tuberculous granuloma determine whether
Externí odkaz:
https://doaj.org/article/0146d91762a245b9bf88c720a16add25
Autor:
Soumia Sid Ahmed, Zoubeida Messali, Larbi Boubchir, Ahmed Bouridane, Sergio Marco, Cédric Messaoudi
Publikováno v:
BMC Biomedical Engineering, Vol 1, Iss 1, Pp 1-12 (2019)
Abstract Background Due to the presence of high noise level in tomographic series of energy filtered transmission electron microscopy (EFTEM) images, alignment and 3D reconstruction steps become so difficult. To improve the alignment process which wi
Externí odkaz:
https://doaj.org/article/14be4f0a581f4eda8eae5027d2dddebc