Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Sergio Marchini"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract Background High-throughput sequencing (HTS) has become the gold standard approach for variant analysis in cancer research. However, somatic variants may occur at low fractions due to contamination from normal cells or tumor heterogeneity; th
Externí odkaz:
https://doaj.org/article/67b9649418b942f78432ff2c6a322de2
Autor:
Martina Vescio, Lara Paracchini, Luca Beltrame, Maurizio D’Incalci, Sergio Marchini, Linda Pattini
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 7, Iss , Pp 100088- (2023)
High grade serous ovarian carcinoma (HGSOC) is a systemic malignancy characterized by metastatic lesions that spread within the peritoneal cavity. Despite initial sensibility to platinum-based chemotherapy, more than 80% of patients experience a rela
Externí odkaz:
https://doaj.org/article/6fc85128e64f4a40b87e1afa50f762cf
Autor:
Elisabeth Digifico, Marco Erreni, Laura Mannarino, Sergio Marchini, Aldo Ummarino, Clément Anfray, Luca Bertola, Camilla Recordati, Daniela Pistillo, Massimo Roncalli, Paola Bossi, Paolo Andrea Zucali, Maurizio D’Incalci, Cristina Belgiovine, Paola Allavena
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMalignant Pleural Mesothelioma (MPM) is an aggressive cancer of the mesothelial lining associated with exposure to airborne non-degradable asbestos fibers. Its poor response to currently available treatments prompted us to explore the biolo
Externí odkaz:
https://doaj.org/article/68711fac11ea42e48295576f8070971b
Autor:
Laura Mannarino, Federica Mirimao, Nicolò Panini, Lara Paracchini, Sergio Marchini, Luca Beltrame, Rosy Amodeo, Federica Grosso, Roberta Libener, Irene De Simone, Giovanni L. Ceresoli, Paolo A. Zucali, Monica Lupi, Maurizio D’Incalci
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-9 (2022)
Abstract Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in malignant pleural mesothelioma (MPM) patients, the mechanisms behind the different selectivity displayed by the various MPM histotypes to this phys
Externí odkaz:
https://doaj.org/article/5bde7304069647c4a6e5b02fd41387ae
Autor:
Fabio Conforti, Laura Pala, Eleonora Pagan, Elena Guerini Rocco, Vincenzo Bagnardi, Emilia Montagna, Giulia Peruzzotti, Tommaso De Pas, Caterina Fumagalli, Silvana Pileggi, Chiara Pesenti, Sergio Marchini, Giovanni Corso, Caterina Marchio’, Anna Sapino, Rossella Graffeo, Laetitia Collet, Philippe Aftimos, Christos Sotiriou, Martine Piccart, Richard D. Gelber, Giuseppe Viale, Marco Colleoni, Aron Goldhirsch
Publikováno v:
Breast, Vol 59, Iss , Pp 94-101 (2021)
Background: We report here for the first time, a comprehensive characterization of biological and clinical features of early-stage triple negative Invasive Lobular Carcinomas(TN-ILCs) Methods: We analyzed all consecutive patients with early-stage TN-
Externí odkaz:
https://doaj.org/article/0e41cdfb84f743128a8f6f2c40685bb2
Autor:
Alessia Salamone, Gaetano Terrone, Rossella Di Sapia, Silvia Balosso, Teresa Ravizza, Luca Beltrame, Ilaria Craparotta, Laura Mannarino, Sara Raimondi Cominesi, Massimo Rizzi, Alberto Pauletti, Sergio Marchini, Luca Porcu, Till S. Zimmer, Eleonora Aronica, Matthew During, Brett Abrahams, Shinichi Kondo, Toshiya Nishi, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease, Vol 173, Iss , Pp 105835- (2022)
Therapies for epilepsy mainly provide symptomatic control of seizures since most of the available drugs do not target disease mechanisms. Moreover, about one-third of patients fail to achieve seizure control. To address the clinical need for disease-
Externí odkaz:
https://doaj.org/article/a8d72f20e7364f5fb631d3c581366d20
Autor:
Stefanie Hiltbrunner, Laura Mannarino, Michaela B. Kirschner, Isabelle Opitz, Angelica Rigutto, Alexander Laure, Michela Lia, Paolo Nozza, Antonio Maconi, Sergio Marchini, Maurizio D’Incalci, Alessandra Curioni-Fontecedro, Federica Grosso
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up to 80% of the MPM cases are linked to asbestos exposure. Even though its use has been banned in the industrialized countries, the cases continue to increase. M
Externí odkaz:
https://doaj.org/article/6ff52d24fb5a455594cd6f686950112c
Autor:
Chiara Romani, Valentina Zizioli, Marco Silvestri, Laura Ardighieri, Mattia Bugatti, Michela Corsini, Paola Todeschini, Sergio Marchini, Maurizio D'Incalci, Laura Zanotti, Antonella Ravaggi, Fabio Facchetti, Angela Gambino, Franco Odicino, Enrico Sartori, Alessandro Davide Santin, Stefania Mitola, Eliana Bignotti, Stefano Calza
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
High-grade serous ovarian carcinoma (HGSOC) usually spreads directly into the peritoneal cavity following a transcoelomic dissemination route, although distant hematogenous metastasis exist and have been reported. However, no tumor markers can curren
Externí odkaz:
https://doaj.org/article/8a3b8f139a7a4efa94b6ab8f116c19a7
Autor:
Lara Paracchini, Luca Beltrame, Lucia Boeri, Federica Fusco, Paolo Caffarra, Sergio Marchini, Diego Albani, Gianluigi Forloni
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-20 (2018)
Abstract Background The typical familial form of Alzheimer’s disease (FAD) accounts for about 5% of total Alzheimer’s disease (AD) cases. Presenilins (PSEN1 and PSEN2) and amyloid-β (A4) precursor protein (APP) genes carry all reported FAD-linke
Externí odkaz:
https://doaj.org/article/30ede54f6a134ce398fff6dcba2adf24
Autor:
Laura Zanotti, Chiara Romani, Laura Tassone, Paola Todeschini, Renata Alessandra Tassi, Elisabetta Bandiera, Giovanna Damia, Francesca Ricci, Laura Ardighieri, Stefano Calza, Sergio Marchini, Luca Beltrame, Germana Tognon, Maurizio D’Incalci, Sergio Pecorelli, Enrico Sartori, Franco Odicino, Antonella Ravaggi, Eliana Bignotti
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background The existence of cancer stem cells (CSCs) within a tumor bulk has been demonstrated for many solid tumors including epithelial ovarian carcinoma (EOC). CSCs have been associated to tumor invasion, metastasis and development of che
Externí odkaz:
https://doaj.org/article/87f29fb63e524c3b83dd910c29002f5f