Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sergio Leal-Ortiz"'
Autor:
Huong T. T. Ha, Sergio Leal-Ortiz, Kriti Lalwani, Shigeki Kiyonaka, Itaru Hamachi, Shreesh P. Mysore, Johanna M. Montgomery, Craig C. Garner, John R. Huguenard, Sally A. Kim
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
During development, pyramidal neurons undergo dynamic regulation of AMPA receptor (AMPAR) subunit composition and density to help drive synaptic plasticity and maturation. These normal developmental changes in AMPARs are particularly vulnerable to ri
Externí odkaz:
https://doaj.org/article/95f494fd563543b49d09449d0553c14b
Publikováno v:
ACS Nano. 17:5632-5643
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e815110e42a2ce6254d308df80ecdb
https://doi.org/10.1021/acsnano.2c11618
https://doi.org/10.1021/acsnano.2c11618
Autor:
Richard Nelson Hall, Uri Weill, Leonard Drees, Sergio Leal-Ortiz, Hongquan Li, Margarita Khariton, Chew Chai, Yuan Xue, Benyamin Rosental, Stephen R. Quake, Alejandro Sánchez Alvarado, Nicholas A. Melosh, Andrew Z. Fire, Jochen C. Rink, Bo Wang
Publikováno v:
Cell Reports: Methods
Planarians have long been studied for their regenerative abilities. Moving forward, tools for ectopic expression of non-native proteins will be of substantial value. Using a luminescent reporter to overcome the strong autofluorescence of planarian ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869b8bd549c733f1634571f7e5ea2131
https://doi.org/10.1016/j.crmeth.2022.100298
https://doi.org/10.1016/j.crmeth.2022.100298
Autor:
Richard Nelson, Hall, Uri, Weill, Leonard, Drees, Sergio, Leal-Ortiz, Hongquan, Li, Margarita, Khariton, Chew, Chai, Yuan, Xue, Benyamin, Rosental, Stephen R, Quake, Alejandro, Sánchez Alvarado, Nicholas A, Melosh, Andrew Z, Fire, Jochen C, Rink, Bo, Wang
Publikováno v:
Cell reports methods. 2(10)
Planarians have long been studied for their regenerative abilities. Moving forward, tools for ectopic expression of non-native proteins will be of substantial value. Using a luminescent reporter to overcome the strong autofluorescence of planarian ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cf1b7af21262f85e3d650432bb70653
https://pubmed.ncbi.nlm.nih.gov/36313809
https://pubmed.ncbi.nlm.nih.gov/36313809
Autor:
Juan A. Godoy, Viviana I. Torres, Pedro Zamorano, Matias Lira, Patricio R Orrego, Duxan Arancibia, Jonathan García, Sergio Leal-Ortiz, Craig C. Garner, Yocelin Cruz, Nibaldo C. Inestrosa, Eckart D. Gundelfinger, Carolina Montenegro-Venegas
Publikováno v:
Molecular neurobiology 56(7), 4620-4638 (2018). doi:10.1007/s12035-018-1378-0
Neurons are highly polarized cells displaying an elaborate architectural morphology. The design of their dendritic arborization and the distribution of their synapses contribute importantly to information processing in the brain. The growth and compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7a0bbba1dd21011eeb40267ce72334
https://pubmed.ncbi.nlm.nih.gov/30374940
https://pubmed.ncbi.nlm.nih.gov/30374940
Autor:
Juan G. Santiago, Sergiu P. Paşca, Sergio Leal-Ortiz, Joseph C. Wu, Haodong Chen, Yuhong Cao, Nicholas A. Melosh, Fikri Birey, Crystal M. Han, Martin Hjort
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Here, we report a method for time-resolved, longitudinal extraction and quantitative measurement of intracellular proteins and mRNA from a variety of cell types. Cytosolic contents were repeatedly sampled from the same cell or population of cells for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001869c635325841754d8cac4ea95035
https://doi.org/10.1073/pnas.1615375114
https://doi.org/10.1073/pnas.1615375114
Autor:
Craig C. Garner, Anna Fejtova, Eckart D. Gundelfinger, Wilko D. Altrock, Hannah Dalke, Nathan D. Okerlund, Sergio Leal-Ortiz, Clarissa L. Waites
Publikováno v:
The EMBO Journal. 32:954-969
The presynaptic active zone (AZ) is a specialized microdomain designed for the efficient and repetitive release of neurotransmitter. Bassoon and Piccolo are two high molecular weight components of the AZ, with hypothesized roles in its assembly and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e24f59013af0db73c946fe88ae1c9f
https://doi.org/10.1038/emboj.2013.27
https://doi.org/10.1038/emboj.2013.27
Autor:
Till F. M. Andlauer, Clarissa L. Waites, Sergio Leal-Ortiz, Stefan J. Sigrist, Craig C. Garner
Publikováno v:
The Journal of Neuroscience. 31:14250-14263
Filamentous (F)-actin is a known regulator of the synaptic vesicle (SV) cycle, with roles in SV mobilization, fusion, and endocytosis. However, the molecular pathways that regulate its dynamic assembly within presynaptic boutons remain unclear. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9800acfd1bdd24d85d85db0d14e2c0d
https://doi.org/10.1523/jneurosci.1835-11.2011
https://doi.org/10.1523/jneurosci.1835-11.2011
Autor:
Janie W. Foote, Craig C. Garner, Dong Li, Christian G. Specht, Sergio Leal-Ortiz, Clarissa L. Waites, Charlotte Butler-Munro, Johanna M. Montgomery, David Genoux
Publikováno v:
The Journal of Physiology. 589:4491-4510
SAP97 is a multidomain scaffold protein implicated in the forward trafficking and synaptic localization of NMDA- and AMPA-type glutamate receptors. Alternative splicing of SAP97 transcripts gives rise to palmitoylated αSAP97 and L27-domain containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a404860865a017c55ca47d8382f6b373
https://doi.org/10.1113/jphysiol.2011.215566
https://doi.org/10.1113/jphysiol.2011.215566
Autor:
Christian G. Specht, Craig C. Garner, Johanna M. Montgomery, Dong Li, Clarissa L. Waites, Sergio Leal-Ortiz, William N. Green, Juliette E. Cheyne, David Genoux, Kai Härtel, Okunola Jeyifous, Renaldo C. Drisdel
Publikováno v:
The Journal of Neuroscience. 29:4332-4345
The synaptic insertion of GluR1-containing AMPA-type glutamate receptors (AMPARs) is critical for synaptic plasticity. However, mechanisms responsible for GluR1 insertion and retention at the synapse are unclear. The synapse-associated protein SAP97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0610003e22695019e01f5bbb929bf57b
https://doi.org/10.1523/jneurosci.4431-08.2009
https://doi.org/10.1523/jneurosci.4431-08.2009