Výsledky vyhledávání - "Sergio L.R. Martins"

Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes

Autor: Dimitrios P. Kontoyiannis, Enrico Orciuolo, Russell E. Lewis, Lisa S. St. John, Sergio L.R. Martins, Krishna V. Komanduri, Marta Stanzani

Publikováno v: Blood. 105:2258-2265

Aspergillus fumigatus (AF) is a ubiquitous mold and is the most common cause of invasive aspergillosis, an important source of morbidity and mortality in immunocompromised hosts. Using cytokine flow cytometry, we assessed the magnitude of functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d95bad20258a5c2a1395cc21512d1bb
https://doi.org/10.1182/blood-2004-09-3421

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Functional assessment and specific depletion of alloreactive human T cells using flow cytometry

Autor: Lisa S. St. John, Sergio L.R. Martins, Eric D. Wieder, John McMannis, Krishna V. Komanduri, Jeffrey J. Molldrem, Richard E. Champlin

Publikováno v: Blood. 104:3429-3436

Human T-cell alloreactivity plays an important role in many disease processes, including the rejection of solid organ grafts and graft-versus-host disease (GVHD) following allogeneic stem cell transplantation. To develop a better understanding of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a877fc67ad4e704b18bbabb195f85f7
https://doi.org/10.1182/blood-2004-05-1918

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CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans

Autor: Krishna V. Komanduri, Sergio L.R. Martins, Daniel R. Couriel, Susan Bryan, John McMannis, Lisa S. St. John, Jeffrey J. Molldrem, Marta Stanzani, Richard E. Champlin, Rima M. Saliba

Publikováno v: Blood. 103:1140-1146

Graft-versus-host disease (GVHD) occurs in an unpredictable fashion after 30% to 50% of matched-related transplantations. The presence of increased frequencies of CD4+CD25+ regulatory T cells in donor grafts has been shown to ameliorate GVHD after al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180457408d8715b6c3dad7a660c94c3d
https://doi.org/10.1182/blood-2003-06-2085

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Naïve and Memory CD4+ T Cells Proliferate and Contribute to Cytokine Production in the Human Alloreactive T Cell Response in Vitro

Autor: Krishna V. Komanduri, Lisa S. St. John, Sergio L.R. Martins

Publikováno v: Blood. 104:4983-4983

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality in the setting of allogeneic stem cell transplantation (SCT). We recently developed a cytokine flow cytometry (CFC)-based assay to assess alloreactivity (Martins, et al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1f8df1dfae08ad474542708f2434355
https://doi.org/10.1182/blood.v104.11.4983.4983

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