Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sergio Jiménez Gambín"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Focused ultrasound (FUS) is a non-invasive and non-ionizing technique which deploys ultrasound waves to induce bio-effects. When paired with acoustically active particles such as microbubbles (MBs), it can open the blood brain barrier (BBB)
Externí odkaz:
https://doaj.org/article/5f65f637ead84df3b4b5621c4907631a
Autor:
Sua Bae, Antonios Pouliopoulos, Robin Ji, Keyu Liu, Sergio Jiménez-Gambín, Omid Yousefian, Danae Kokossis, Lawrence Honig, Elisa Konofagou
Publikováno v:
The Journal of the Acoustical Society of America. 153:A315-A315
We present real-time cavitation monitoring and mapping in a clinical trial for blood-brain barrier (BBB) opening in Alzheimer’s disease (AD) patients using a neuronavigation-guided focused ultrasound (FUS) system. Six AD patients (N = 6, age = 68.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e18c07a9fb5deadfe144d06aada893f1
https://doi.org/10.1121/10.0018978
https://doi.org/10.1121/10.0018978
Autor:
Antonios N. Pouliopoulos, Elisa E. Konofagou, Jose M. Benlloch, Noé Jiménez, Francisco Camarena, Sergio Jiménez-Gambín
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
IEEE Trans Biomed Eng
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IEEE Trans Biomed Eng
[EN] Transcranial focused ultrasound (FUS) in conjunction with circulating microbubbles injection is the sole non-invasive technique that temporally and locally opens the blood-brain barrier (BBB), allowing targeted drug delivery into the central ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd800c02790562e28919082b675b088
http://hdl.handle.net/10251/187196
http://hdl.handle.net/10251/187196
Autor:
Elisa E. Konofagou, Zachary K. Englander, Noé Jiménez, Stergios Zacharoulis, Antonios N. Pouliopoulos, Cheng-Chia Wu, Sergio Jiménez-Gambín, Francisco Camarena
Publikováno v:
2021 IEEE International Ultrasonics Symposium (IUS).
Targeted drug delivery to enhance chemotherapy treatments in brain tumors can be achieved by opening the blood-brain barrier in a non-invasive, transient, localized, safe manner by using focused ultrasound (FUS) and microbubbles. However, as brain tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac4c022f60d7b67eeae79c1fae7e5de
https://doi.org/10.1109/ius52206.2021.9593797
https://doi.org/10.1109/ius52206.2021.9593797
Autor:
Sergio Jiménez Gambín
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[ES] El tratamiento de enfermedades neurológicas está muy limitado por la ineficiente penetración de los fármacos en el tejido cerebral dañado debido a la barrera hematoencefálica (BHE), lo que imposibilita mejorar la salud del paciente. La BHE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0450d75a4d7c78b1c6834b8a5773792e
https://hdl.handle.net/10251/171373
https://hdl.handle.net/10251/171373
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[EN] Acoustic vortex beams have great potential for contactless particle manipulation and torque-based biomedical applications. However, when focusing acoustic waves through aberration layers such as the human skull at ultrasonic frequencies results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbb6aca89e0e82fefeeb543f3460c17
https://doi.org/10.1103/physrevapplied.14.054070
https://doi.org/10.1103/physrevapplied.14.054070
Autor:
Francisco Camarena, Antonios N. Pouliopoulos, Sergio Jiménez-Gambín, Elisa E. Konofagou, Noé Jiménez, Jose M. Benlloch
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[EN] Focused ultrasound (FUS) with microbubbles allows for non-invasive targeted drug delivery into the central nervous system (CNS) by temporally and locally disrupting the bloodbrain barrier (BBB). However, current FUS technologies are not able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd51feffe0c3fc4475acdbf9fdceadd
https://doi.org/10.1109/ius46767.2020.9251487
https://doi.org/10.1109/ius46767.2020.9251487
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[EN] Single-element focused ultrasound devices have demonstrated its ability to non-invasively open the Blood Brain Barrier. However, skull irregularities and absorption produce strong aberrations in the ultrasound focus. Recently, 3D-printed acousti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bab8e5b14e054fb4a01d150919f3e9
https://doi.org/10.1109/ius46767.2020.9251769
https://doi.org/10.1109/ius46767.2020.9251769
Publikováno v:
Scientific Reports
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
[EN] We report zero-th and high-order acoustic Bessel beams with broad depth-of-field generated using acoustic holograms. While the transverse field distribution of Bessel beams generated using traditional passive methods is correctly described by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11632ffd04c8cecfeb4002cac513d20f
https://doi.org/10.1038/s41598-019-56369-z
https://doi.org/10.1038/s41598-019-56369-z
Publikováno v:
2019 IEEE International Ultrasonics Symposium (IUS).
Focused ultrasound is currently used in many emerging therapeutic applications for the non-invasive treatment of neurological disorders and pathologies inside the central nervous system. However, the accurate focusing of ultrasound beams at the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::900f61cd2c3ab01ce4155865a9c6c6c5
https://doi.org/10.1109/ultsym.2019.8925899
https://doi.org/10.1109/ultsym.2019.8925899