Mucoadhesive Budesonide Solution for the Treatment of Pediatric Eosinophilic Esophagitis

Autor: Antonio Spennacchio, Antonio Lopalco, Giuseppe Francesco Racaniello, Annalisa Cutrignelli, Flavia Maria la Forgia, Sergio Fontana, Fernanda Cristofori, Ruggiero Francavilla, Angela Assunta Lopedota, Nunzio Denora

Publikováno v: Pharmaceuticals, Vol 17, Iss 5, p 550 (2024)

Eosinophilic Esophagitis is an antigen-mediated inflammatory disease characterized by thickening of the esophageal wall, leading to dysphagia, vomiting, reflux, and abdominal pain. This disease can be treated with a therapeutic approach ranging from

Externí odkaz: https://doaj.org/article/d611958452564cc6b0018029bfd2effd

The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia

Autor: Fatima Maqoud, Nicola Zizzo, Antonietta Mele, Nunzio Denora, Giuseppe Passantino, Rosa Scala, Annalisa Cutrignelli, Antonella Tinelli, Valentino Laquintana, Flavia laForgia, Sergio Fontana, Massimo Franco, Angela Assunta Lopedota, Domenico Tricarico

Publikováno v: Pharmacology Research & Perspectives, Vol 8, Iss 3, Pp n/a-n/a (2020)

Abstract The efficacy of minoxidil (MXD) ethanolic solutions (1%‐5% w/v) in the treatment of androgenetic alopecia is limited by adverse reactions. The toxicological effects of repeated topical applications of escalating dose (0.035%‐3.5% w/v) an

Externí odkaz: https://doaj.org/article/2b598d239ed24be79ab832f29cc8f374

An Innovative Synbiotic Formulation Decreases Free Serum Indoxyl Sulfate, Small Intestine Permeability and Ameliorates Gastrointestinal Symptoms in a Randomized Pilot Trial in Stage IIIb-IV CKD Patients

Autor: Carmela Cosola, Maria Teresa Rocchetti, Ighli di Bari, Paola Maria Acquaviva, Valentina Maranzano, Simone Corciulo, Agostino Di Ciaula, Domenica Maria Di Palo, Flavia Maria La Forgia, Sergio Fontana, Maria De Angelis, Piero Portincasa, Loreto Gesualdo

Publikováno v: Toxins, Vol 13, Iss 5, p 334 (2021)

Proteolytic dysbiosis of the gut microbiota has been recognized as both a typical feature of chronic kidney disease (CKD) and a risk factor for its progression. Blood accumulation of gut-derived uremic toxins (UTs) like indoxyl sulfate (IS) and p-cre

Externí odkaz: https://doaj.org/article/e02faf7dd81c4cb09ce42768325523b7

In Vitro Selection of Probiotics, Prebiotics, and Antioxidants to Develop an Innovative Synbiotic and Testing Its Effect in Reducing Uremic Toxins

Autor: Mirco Vacca, Giuseppe Celano, Marcello Salvatore Lenucci, Sergio Fontana, Flavia Maria la Forgia, Fabio Minervini, Aurelia Scarano, Angelo Santino, Giuseppe Dalfino, Loreto Gesualdo, Maria De Angelis

Publikováno v: Microorganisms (2021).
info:cnr-pdr/source/autori:Mirco Vacca, Giuseppe Celano, Marcello Salvatore Lenucci, Sergio Fontana, Flavia Maria la Forgia, Fabio Minervini, Aurelia Scarano, Angelo Santino, Giuseppe Dalfino, Loreto Gesualdo, Maria De Angelis/titolo:In Vitro Selection of Probiotics, Prebiotics, and Antioxidants to Develop an Innovative Synbiotic and Testing Its Effect in Reducing Uremic Toxins/doi:/rivista:Microorganisms/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume

We aimed to develop an innovative synbiotic formulation for use in reducing dysbiosis, uremic toxins (e.g., p-cresol and indoxyl sulfate), and, consequently, the pathognomonic features of patients with chronic kidney disease (CKD). Twenty-five probio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::9c518528cc4e29dec65efbbde8b784bb
http://www.cnr.it/prodotto/i/454812

Stability data of extemporaneous suspensions of hydroxychloroquine sulphate in oral liquid bases after tablet manipulation

Autor: Nunzio Denora, Antonio Pepe, Massimo Franco, Annalisa Cutrignelli, Angela Lopedota, Valentino Laquintana, Antonio Lopalco, Mara Perrone, Sergio Fontana

Publikováno v: Data in Brief
Data in Brief, Vol 33, Iss, Pp 106575-(2020)

Hydroxychloroquine is a well-known anti-malarial and anti-rheumatic drug that has garnered recently unprecedented attention as potential therapeutic agent against virus infections. Hydroxychloroquine sulphate is authorized in the EU as film-coated ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd66811f76eeace5b1f7adbf83c6918
http://europepmc.org/articles/PMC8129641