Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sergio Enríquez-Flores"'
Autor:
Miriam E. Reyna-Fabián, Liliana Fernández-Hernández, Sergio Enríquez-Flores, David Apam-Garduño, Carolina Prado-Larrea, Go Hun Seo, Rin Khang, Vianney Cortés-González
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Inherited and developmental eye diseases are quite diverse and numerous, and determining their genetic cause is challenging due to their high allelic and locus heterogeneity. New molecular approaches, such as whole exome sequencing (WES), ha
Externí odkaz:
https://doaj.org/article/9bc4b80918754f4e9caadfb4afd42cdf
Autor:
Ignacio de la Mora-de la Mora, Itzhel García-Torres, Luis Antonio Flores-López, Gabriel López-Velázquez, Gloria Hernández-Alcántara, Saúl Gómez-Manzo, Sergio Enríquez-Flores
Publikováno v:
Molecules, Vol 29, Iss 21, p 5047 (2024)
Triosephosphate isomerase (TPI) dysfunction is a critical factor in diverse pathological conditions. Deficiencies in TPI lead to the accumulation of toxic methylglyoxal (MGO), which induces non-enzymatic post-translational modifications, thus comprom
Externí odkaz:
https://doaj.org/article/af710411fdd9494393713ce2d7fc65e9
Autor:
Luis A. Flores-López, Ignacio De la Mora-De la Mora, Claudia M. Malagón-Reyes, Itzhel García-Torres, Yoalli Martínez-Pérez, Gabriela López-Herrera, Gloria Hernández-Alcántara, Gloria León-Avila, Gabriel López-Velázquez, Alberto Olaya-Vargas, Saúl Gómez-Manzo, Sergio Enríquez-Flores
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1295 (2024)
T-cell acute lymphoblastic leukemia (T-ALL) is a challenging childhood cancer to treat, with limited therapeutic options and high relapse rates. This study explores deamidated triosephosphate isomerase (dTPI) as a novel therapeutic target. We hypothe
Externí odkaz:
https://doaj.org/article/b5729f43f091488fb264b0a8adec80dc
Autor:
Itzhel García-Torres, Ignacio De la Mora-De la Mora, Gabriel López-Velázquez, Nallely Cabrera, Luis Antonio Flores-López, Ingeborg Becker, Juliana Herrera-López, Roberto Hernández, Ruy Pérez-Montfort, Sergio Enríquez-Flores
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Trypanosoma cruzi is the causative agent of American trypanosomiasis, which mainly affects populations in Latin America. Benznidazole is used to control the disease, with severe effects in patients receiving this chemotherapy. Previous studies have d
Externí odkaz:
https://doaj.org/article/3f1c171e8e7b4a26bbf02dd8e5581944
Autor:
Víctor Martínez-Rosas, Gabriel Navarrete-Vázquez, Daniel Ortega-Cuellar, Roberto Arreguin-Espinosa, Verónica Pérez de la Cruz, Ernesto Calderón-Jaimes, Sergio Enríquez-Flores, Carlos Wong-Baeza, Isabel Baeza-Ramírez, Laura Morales-Luna, Montserrat Vázquez-Bautista, Miriam Abigail Rojas-Alarcón, Beatriz Hernández-Ochoa, Saúl Gómez-Manzo
Publikováno v:
Molecules, Vol 29, Iss 11, p 2585 (2024)
Metronidazole (MTZ) is the most common drug used against Trichomonas vaginalis (T. vaginalis) infections; however, treatment failures and high rates of recurrence of trichomoniasis have been reported, suggesting the presence of resistance in T. vagin
Externí odkaz:
https://doaj.org/article/be13a580f5d943b0afbe07274612fad9
Autor:
Sergio Enríquez-Flores, Luis A. Flores-López, Ignacio De la Mora-De la Mora, Itzhel García-Torres, Isabel Gracia-Mora, Pedro Gutiérrez-Castrellón, Cynthia Fernández-Lainez, Yoalli Martínez-Pérez, Alberto Olaya-Vargas, Paul de Vos, Gabriel López-Velázquez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Human triosephosphate isomerase (HsTIM) is a central glycolytic enzyme and is overexpressed in cancer cells with accelerated glycolysis. Triple-negative breast cancer is highly dependent on glycolysis and is typically treated with a combinat
Externí odkaz:
https://doaj.org/article/8e40f3105af14974bb2c5361fb6ece02
Autor:
Sergio Enríquez-Flores, Ignacio De la Mora-De la Mora, Itzhel García-Torres, Luis A. Flores-López, Yoalli Martínez-Pérez, Gabriel López-Velázquez
Publikováno v:
Molecules, Vol 28, Iss 16, p 6163 (2023)
Cancer involves a series of diseases where cellular growth is not controlled. Cancer is a leading cause of death worldwide, and the burden of cancer incidence and mortality is rapidly growing, mainly in developing countries. Many drugs are currently
Externí odkaz:
https://doaj.org/article/594ffe6f4c8d4dd4914b5b7e377db877
Autor:
Beatriz Hernández-Ochoa, Víctor Martínez-Rosas, Laura Morales-Luna, Ernesto Calderón-Jaimes, Luz María Rocha-Ramírez, Daniel Ortega-Cuellar, Yadira Rufino-González, Abigail González-Valdez, Roberto Arreguin-Espinosa, Sergio Enríquez-Flores, Rosa Angélica Castillo-Rodríguez, Noemí Cárdenas-Rodríguez, Carlos Wong-Baeza, Isabel Baeza-Ramírez, Saúl Gómez-Manzo
Publikováno v:
Molecules, Vol 27, Iss 24, p 8902 (2022)
Protozoan parasites, such as Giardia lamblia and Trichomonas vaginalis, cause the most prevalent infections in humans in developing countries and provoke significant morbidity and mortality in endemic countries. Despite its side-effects, metronidazol
Externí odkaz:
https://doaj.org/article/8de6474a1baa4abd9bdd044c52358ad8
Autor:
Víctor Martínez-Rosas, Beatriz Hernández-Ochoa, Gabriel Navarrete-Vázquez, Carlos Martínez-Conde, Fernando Gómez-Chávez, Laura Morales-Luna, Abigail González-Valdez, Roberto Arreguin-Espinosa, Sergio Enríquez-Flores, Verónica Pérez de la Cruz, Rodrigo Aguayo-Ortiz, Carlos Wong-Baeza, Isabel Baeza-Ramírez, Saúl Gómez-Manzo
Publikováno v:
Molecules, Vol 27, Iss 4, p 1174 (2022)
Trichomoniasis is a sexually transmitted disease with a high incidence worldwide, affecting 270 million people. Despite the existence of a catalog of available drugs to combat this infection, their extensive use promotes the appearance of resistant T
Externí odkaz:
https://doaj.org/article/d7eb153ffb6943c69fc122bb7ddd4799
Autor:
Laura Morales-Luna, Abigail González-Valdez, Beatriz Hernández-Ochoa, Roberto Arreguin-Espinosa, Daniel Ortega-Cuellar, Rosa Angélica Castillo-Rodríguez, Víctor Martínez-Rosas, Noemi Cárdenas-Rodríguez, Sergio Enríquez-Flores, Luis Miguel Canseco-Ávila, Verónica Pérez de la Cruz, Fernando Gómez-Chávez, Saúl Gómez-Manzo
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1678 (2021)
Giardia lamblia is a single-celled eukaryotic parasite with a small genome and is considered an early divergent eukaryote. The pentose phosphate pathway (PPP) plays an essential role in the oxidative stress defense of the parasite and the production
Externí odkaz:
https://doaj.org/article/06fd55545fe24d0a80fe28862c8d135f